CAS 440-17-5
:Cloridrato de trifluoperazina
Descrição:
Cloridrato de trifluoperazina é um medicamento antipsicótico típico que pertence à classe das fenotiazinas, utilizado principalmente no tratamento da esquizofrenia e outros transtornos psicóticos. Funciona como um antagonista dos receptores de dopamina, direcionando-se particularmente aos receptores D2 no cérebro, o que ajuda a aliviar sintomas como alucinações e delírios. O composto aparece como um pó cristalino branco a off-white e é solúvel em água, tornando-o adequado para várias formulações farmacêuticas. Sua estrutura química inclui um grupo trifluorometilo, que contribui para sua potência e eficácia. A trifluoperazina também é conhecida por suas propriedades sedativas e pode ser usada para gerenciar ansiedade e agitação. No entanto, pode ter efeitos colaterais, incluindo sintomas extrapiramidais, sedação e potenciais efeitos cardiovasculares. Devido ao seu perfil farmacológico, é essencial monitorar os pacientes quanto a reações adversas e ajustar as dosagens conforme necessário. Assim como todos os antipsicóticos, o uso de trifluoperazina deve ser cuidadosamente considerado e gerenciado por profissionais de saúde.
Fórmula:C21H24F3N3S·2ClH
InChI:InChI=1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H
Chave InChI:InChIKey=BXDAOUXDMHXPDI-UHFFFAOYSA-N
SMILES:C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(C(F)(F)F)C3.Cl
Sinónimos:- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluormethyl)-10H-phenothiazinhydrochlorid
- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride
- 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine hydrochloride
- 10-[3-(4-méthylpipérazin-1-yl)propyl]-2-(trifluorométhyl)-10H-phénothiazine chlorhydrate
- 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride
- 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2)
- 10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:1)
- 10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, monohydrochloride
- 2-Trifluoromethyl-10-[3-(1-methyl-4-piperazinyl)propyl]phenothiazine dihydrochloride
- Eskazine
- Eskazinyl
- Fluoperazine
- Jatroneural
- Modalina
- Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride
- Skf 5019
- Stelazine
- Stellasil
- Terfluzine
- Trazine
- Trifluoperazine HCl
- Trifluoperazine dihydrochloride
- Trifluoperazine hydrochloride (VAN)
- Trifluoperazine hydrochloride [JAN]
- Trifluoroperazine dihydrochloride
- Trifluoroperazine hydrochloride
- Triftazin
- Triphthasine
- Triphthazine
- Triphthazine dihydrochloride
- Tryptazine
- Tryptazine dihydrochloride
- Ver mais sinónimos
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18 produtos.
Trifluoperazine Dihydrochloride
CAS:Fórmula:C21H24F3N3S·2HClPureza:>98.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:480.42Trifluoperazine Hydrochloride
CAS:<p>Antidepressants, tranquilizers and other pschotherapeutic agents</p>Fórmula:C21H24F3N3S·2HClCor e Forma:PowderPeso molecular:407.1643Trifluoperazine dihydrochloride
CAS:<p>Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.</p>Fórmula:C21H26Cl2F3N3SPureza:99.57% - 99.96%Cor e Forma:Cream Fine PowderPeso molecular:480.43Trifluoperazine dihydrochloride, EP grade
CAS:Fórmula:C21H24F3N3S·2HClPureza:99.0 - 101.0 % (dried substance)Cor e Forma:White to pale yellow crystalline powderPeso molecular:480.42Trifluoperazine dihydrochloride
CAS:<p>Trifluoperazine dihydrochloride</p>Pureza:≥98%Peso molecular:480.43g/molTrifluoperazine DiHCl
CAS:Fórmula:C21H24F3N3S·2HClCor e Forma:White To Off-White SolidPeso molecular:407.50 2*36.46Trifluoperazine dihydrochloride
CAS:Fórmula:C21H24F3N3S·2HClPureza:98.0 - 101.0 % (dried basis)Cor e Forma:Whtie to pale yellow crystalline powderPeso molecular:480.42Trifluoperazine Hydrochloride
CAS:Produto ControladoFórmula:C21H24F3N3SClHCor e Forma:NeatPeso molecular:480.42Trifluoperazine Dihydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Antipsychotic.<br>References Flanagan, T.L., et al.: J. Pharm. Sci., 51, 996 (1962), Post., A., et al.: Anal. Profiles Drug Subs., 9, 543 (1980)<br></p>Fórmula:C21H24F3N3S·2ClHCor e Forma:NeatPeso molecular:480.42Trifluoperazine dihydrochloride
CAS:Produto Controlado<p>Trifluoperazine is a drug that belongs to the class of selective p-glycoprotein (p-gp) inhibitors. It has been shown to decrease cytosolic calcium levels and glucose-dependent insulinotropic peptide (glp-1) levels in rats. Trifluoperazine has also been shown to have constant pressure and physiological effects on energy metabolism in rat adipocytes at an optimum concentration of 1 μM. In addition, trifluoperazine inhibits the activity of target enzymes such as neuronal death and intracellular calcium levels. The optimal concentration for trifluoperazine is 1 μM, which can be determined by electrochemical impedance spectroscopy. Trifluoperazine also binds to fluorescence probes, which may be used for imaging purposes.</p>Fórmula:C21H26Cl2F3N3SPureza:(Titration) Min. 98.0%Cor e Forma:PowderPeso molecular:480.42 g/mol
