CAS 4419-39-0
:Beclometasona
Descrição:
Beclometasona é um corticosteroide sintético utilizado principalmente por suas propriedades anti-inflamatórias e imunossupressoras. É comumente administrado na forma de inaladores, sprays nasais ou formulações tópicas para tratar condições como asma, rinite alérgica e vários distúrbios de pele. A substância funciona inibindo a liberação de mediadores inflamatórios, reduzindo assim o inchaço e a irritação nos tecidos afetados. Beclometasona tem uma biodisponibilidade sistêmica relativamente baixa quando inalada, o que minimiza os potenciais efeitos colaterais em comparação com corticosteroides sistêmicos. Sua estrutura química apresenta uma espinha dorsal esteroide com grupos funcionais específicos que contribuem para sua potência e seletividade pelos receptores de glicocorticoides. O composto é geralmente bem tolerado, embora o uso a longo prazo possa levar a efeitos colaterais como supressão adrenal ou irritação local. Assim como com qualquer medicamento, é essencial usar Beclometasona sob supervisão médica para garantir a dosagem apropriada e monitorar quaisquer efeitos adversos.
Fórmula:C22H29ClO5
InChI:InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
Chave InChI:InChIKey=NBMKJKDGKREAPL-DVTGEIKXSA-N
SMILES:Cl[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Sinónimos:- (11β,16β)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
- (8S,10S,11S,13S,16S)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- 4419-39-0
- 9-Chloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
- 9-Chloro-11β,17,21-trihydroxy-16β-methyl-pregna-1,4-diene-3,20-dione
- 9-Chloro-16β-methylprednisolone
- 9α-Chloro-16β-methylprednisolone
- Beclometason
- Beclometasona
- Beclometasone
- Beclometasone 17,21-Dipropionate
- Becolvent
- Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-
- Ver mais sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
10 produtos.
Beclomethasone (9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione)
CAS:Halogenated derivatives of adrenal cortical hormonesFórmula:C22H29ClO5Cor e Forma:White PowderPeso molecular:408.17035Beclometasone (Beclomethasone)
CAS:Fórmula:C22H29ClO5Cor e Forma:White To Off-White SolidPeso molecular:408.92GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Produto Controlado- 105102-22-5
- 1177-87-3
- 124-94-7
- 13609-67-1
- 14484-47-0
- 1524-88-5
- 2135-17-3
- 2152-44-5
- 25122-46-7
- 25122-57-0
- 3093-35-4
- 33564-31-7
- 356-12-7
- 378-44-9
- 3801-06-7
- 3870-07-3
- 426-13-1
- 4419-39-0
- 50-02-2
- 50-03-3
- 50-04-4
- 50-23-7
- 50-24-8
- 51022-69-6
- 51333-22-3
- 514-36-3
- 53-06-5
- 5534-09-8
- 5593-20-4
- 57524-89-7
- 66734-13-2
- 67-78-7
- 73771-04-7
- 76-25-5
- 80474-14-2
- 83-43-2
- 987-24-6
Cor e Forma:Mixture9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (Beclometasone)
CAS:Produto ControladoFórmula:C22H29ClO5Cor e Forma:NeatPeso molecular:408.92Beclometasone
CAS:Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.Fórmula:C22H29ClO5Pureza:99.41% - 99.68%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:408.92Beclomethasone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).<br>References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),<br></p>Fórmula:C22H29ClO5Cor e Forma:Off-WhitePeso molecular:408.92Beclomethasone - 98% min
CAS:Produto Controlado<p>Beclomethasone is a synthetic glucocorticoid that has significant effects on the bronchial system. It is used for the treatment of bronchial asthma and other diseases of the airways. Beclomethasone may be administered by inhalation, orally, or topically. Beclomethasone binds to cytoplasmic receptors in target cells and inhibits phospholipases, which are enzymes that release arachidonic acid from cell membranes. This process inhibits the production of leukotrienes, prostaglandins, and thromboxanes-all compounds that have been implicated in inflammation and bronchial asthma. The pharmacokinetic profile of Beclomethasone includes a high volume of distribution and low protein binding. Beclomethasone has been shown to inhibit nuclear receptors such as PPARα and GR, which regulate gene transcription for lipid metabolism.</p>Fórmula:C22H29ClO5Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:408.92 g/molBeclomethasone - 95% min
CAS:Produto ControladoBeclomethasone is a synthetic glucocorticoid that has been approved for the treatment of asthma and inflammatory bowel disease. It reduces inflammation by suppressing the immune system response. Beclomethasone has also been used in clinical studies to treat bronchial, bowel disease, and natriuretic effects due to its ability to increase magnesium levels in the body. Clinical trials have shown that beclomethasone can be used as an effective therapy for asthma. This drug also has anti-inflammatory properties and may be useful in treating infectious diseases such as tuberculosis. Beclomethasone has been shown to be effective against many different types of bacteria including Mycobacterium tuberculosis and Streptococcus pneumoniae.Fórmula:C22H29ClO5Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:408.92 g/mol
