CAS 444-29-1

1-Iodo-2-(trifluorometil)benzeno

Descrição:

1-Iodo-2-(trifluorometil)benzeno, com o número CAS 444-29-1, é um composto aromático caracterizado pela presença de um átomo de iodo e um grupo trifluorometila (-CF3) ligado a um anel de benzeno. Este composto é tipicamente um líquido incolor a amarelo pálido com um odor distinto. É conhecido por sua densidade relativamente alta e baixa solubilidade em água, tornando-se mais solúvel em solventes orgânicos. A presença do grupo trifluorometila confere propriedades eletrônicas únicas, aumentando sua reatividade em várias reações químicas, particularmente em substituição nucleofílica e substituição aromática eletrofílica. Além disso, o átomo de iodo pode servir como um grupo de saída em reações, facilitando a síntese de outros compostos. Devido à sua natureza halogenada, 1-Iodo-2-(trifluorometil)benzeno pode exibir atividade biológica e é de interesse na química medicinal e na ciência dos materiais. O manuseio e armazenamento adequados são essenciais, pois pode representar riscos à saúde e ao meio ambiente.

Fórmula: C₇H₄F₃I

InChI: InChI=1/C7H4F3I/c8-7(9,10)5-3-1-2-4-6(5)11/h1-4H

Chave InChI: InChIKey=IGZGUYVVBABKOY-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(I)C=CC=C1

Sinónimos:

• .alpha.,.alpha.,.alpha.-Trifluoro-o-iodo toluene
• 1-Iod-2-(trifluormethyl)benzol
• 1-Iodo-2-(trifluoromethyl)benzene
• 1-Trifluoromethyl-2-iodobenzene
• 2-(Trifluoromethyl)iodobenzene
• 2-Iodo-1-trifluoromethylbenzene
• 2-Iodobenzotrifluoride
• 2-Trifluoromethylphenyl iodide
• Benzene, 1-iodo-2- (trifluoromethyl)-
• NSC 88291
• Toluene, alpha,alpha,alpha-trifluoro-o-iodo-
• Toluene, α,α,α-trifluoro-o-iodo-
• alpha,alpha,alpha-Trifluoro-2-iodotoluene
• o-(Trifluoromethyl)iodobenzene
• o-Iodobenzotrifluoride
• o-Trifluoromethyliodobenzene
• α,α,α-Trifluoro-o-iodotoluene
• 2-(Trifluoromethyl)iodobenzene, 2-Iodo-α,α,α-trifluorotoluene
• 2-Trifluoromethyliodobenzene
• 2-Iodobenztrifluoride
• 2-Iodobenzotrifluoride (stabilized with Copper chip)
• 2-IODOBENZOTRIFLUORIDE 99%
• alpha,alpha,alpha-Trifluoro-o-iodotoluene
• o-Iodo-alpha,alpha,alpha-trifluorotoluene
• 2-Iodobenzotrifluoride,99%
• 1-iodo-2-(trifluoromethyl)-benzen
• 2-IODO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE
• O-IODINE TRIFLUORO TOLUENE

2-Iodobenzotrifluoride (stabilized with Copper chip)

CAS: 444-29-1

Fórmula: C₇H₄F₃I

Pureza: >98.0%(GC)

Cor e Forma: Colorless to Light orange to Yellow clear liquid

Peso molecular: 272.01

Ref: 3B-I0383

2-Iodobenzotrifluoride, 99%

CAS: 444-29-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₇H₄F₃I

Pureza: 99%

Cor e Forma: Liquid, Clear colorless to yellow or pale green

Peso molecular: 272.01

Ref: 02-A15698

2-Iodobenzotrifluoride

CAS: 444-29-1

Fórmula: C₇H₄F₃I

Pureza: 98%

Cor e Forma: Liquid

Peso molecular: 272.0063

Ref: IN-DA0039E1

2-Iodobenzotrifluoride

CAS: 444-29-1

2-Iodobenzotrifluoride

Fórmula: C₇H₄F₃I

Pureza: 98%

Cor e Forma: colourless to light yellow liquid

Peso molecular: 272.01g/mol

Ref: 54-PC4890

2-Iodobenzotrifluoride

CAS: 444-29-1

2-Iodobenzotrifluoride is a chemical compound that inhibits protein synthesis by binding to the aryl boronic acid groups of proteins. This compound also has anti-inflammatory properties and can be used as a control agent for inflammatory diseases. 2-Iodobenzotrifluoride is soluble in hydrocarbon solvents and reacts with sodium ions to produce sodium-dependent glucose, which can be used as an energy source for cells. The trifluoromethyl group of 2-iodobenzotrifluoride binds to the amino acids serine and histidine, inhibiting their activity. It also inhibits other enzymes such as cholesteryl ester transfer protein and carbonic anhydrase, which are involved in the production of cholesterol.
2-Iodobenzotrifluoride is also able to inhibit nucleophilic groups such as cysteine thiols (SH) and glut

Fórmula: C₇H₄F₃I

Pureza: Min. 95%

Cor e Forma: Clear Liquid

Peso molecular: 272.01 g/mol

Ref: 3D-FI37781

2-Iodobenzotrifluoride

CAS: 444-29-1

Fórmula: C₇H₄F₃I

Pureza: 98%

Cor e Forma: Liquid

Peso molecular: 272.009

Ref: 10-F001194

2-Iodobenzotrifluoride

Produto Controlado

CAS: 444-29-1

Applications 2-Iodobenzotrifluoride acts as a reagent in the preparation, cyclooxygenase-1 inhibitory activity, and docking studies of aminoalkoxyphenylbenzamides. Prepartion and SAR of tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors.
References Fukai, R., et al.: ChemMedChem, 6, 550 (2011); Muthukaman, N., et al.: Bioorg. Med. Chem. Lett., 27, 2594 (2017)

Fórmula: C₇H₄F₃I

Cor e Forma: Neat

Peso molecular: 272.01

Ref: TR-I685630