CAS 446-72-0

Genisteína

Descrição:

Genisteína é um isoflavonoide que ocorre naturalmente, encontrado principalmente em soja e outras leguminosas. Pertence à classe dos fitoestrógenos, que são compostos de origem vegetal que podem imitar o estrogênio no corpo. Genisteína tem uma fórmula molecular de C15H10O5 e um peso molecular de aproximadamente 270,24 g/mol. Este composto exibe uma variedade de atividades biológicas, incluindo propriedades antioxidantes, anti-inflamatórias e potenciais anticancerígenas. Sabe-se que Genisteína interage com os receptores de estrogênio, o que pode influenciar o crescimento e a diferenciação celular. Além disso, foi estudado por seu papel potencial na redução do risco de cânceres relacionados a hormônios, como câncer de mama e próstata. Genisteína também é reconhecido por sua capacidade de modular várias vias de sinalização, incluindo aquelas envolvidas na regulação do ciclo celular e na apoptose. Sua solubilidade é geralmente maior em solventes orgânicos do que em água, e é frequentemente utilizado em suplementos dietéticos e alimentos funcionais devido às suas propriedades promotoras de saúde. No geral, Genisteína é um composto de grande interesse tanto na ciência nutricional quanto na farmacologia.

Fórmula: C₁₅H₁₀O₅

InChI: InChI=1/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H

Chave InChI: InChIKey=TZBJGXHYKVUXJN-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC=C1C3=CC=C(O)C=C3)=CC(O)=CC2O

Sinónimos:

• 4',5,7-Trihydroxyisoflavone
• 4′,5,7-Trihydroxyisoflavone
• 5,7,4'-Trihydroxyisoflavone
• 5,7-Dihidroxi-3-(4-Hidroxifenil)-4-Benzopirona
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyron
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
• Baichanin A
• Bio 300
• Bonistein
• Climagen F
• Csu 1999
• Fw 635I-2
• GeniVida
• Genistein
• Genisteol
• Genisterin
• Genistin aglycone
• Isoflavone, 4',5,7-trihydroxy-
• Isoflavone, 4′,5,7-trihydroxy-
• Npi 031L
• Nsc 36586
• Prunetol
• Sipi 807-1
• Sophoricol
• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
• C.I. 75610
• Natural Genistein
• genistein(synthetic)
• Genistein98%,99%
• AKOS NCG1-0029
• GENISTEIN FROM SOYBEAN 98%(HPLC)
• 5,7-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE
• differenola
• 4’,5,7-trihydroxy-isoflavon
• GENISTEIN FROM GLYCINE MAX (SOYBEAN)

Genistein

CAS: 446-72-0

Fórmula: C₁₅H₁₀O₅

Pureza: >98.0%(HPLC)

Cor e Forma: White to Light yellow to Light orange powder to crystal

Peso molecular: 270.24

Ref: 3B-G0272

4',5,7-Trihydroxyisoflavone, 99+%

CAS: 446-72-0

Inhibitor of tyrosine protein kinase

Fórmula: C₁₅H₁₀O₅

Pureza: 99+%

Cor e Forma: Off-white to pale brown, Powder

Peso molecular: 270.24

Ref: 02-J63241

Genistein

CAS: 446-72-0

Genistein analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₁₅H₁₀O₅

Pureza: (HPLC) ≥99%

Cor e Forma: Powder

Peso molecular: 270.24

Ref: 11-1372S

Genistein

CAS: 446-72-0

Aromatic heterocyclic pesticides with oxygen hetero-atom(s) only, nesoi

Fórmula: C₁₅H₁₀O₅

Cor e Forma: White Beige Brown Powder

Peso molecular: 270.05282

Ref: 45-1288816

4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-

CAS: 446-72-0

Fórmula: C₁₅H₁₀O₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 270.2369

Ref: IN-DA00I8G3

Genistein

CAS: 446-72-0

Fórmula: C₁₅H₁₀O₅

Pureza: (HPLC) ≥ 98.0%

Cor e Forma: White, off-white, light yellow or grey-beige powder

Peso molecular: 270.24

Ref: 7W-GP7710

Genistein

CAS: 446-72-0

Genistein

Pureza: ≥98%

Peso molecular: 270.24g/mol

Ref: 54-BUP14853

Genistein

CAS: 446-72-0

Fórmula: C₁₅H₁₀O₅

Cor e Forma: Neat

Peso molecular: 270.24

Ref: 04-C13999800

Genistein

Produto Controlado

CAS: 446-72-0

Fórmula: C₁₅H₁₀O₅

Cor e Forma: Neat

Peso molecular: 270.24

Ref: 86-MM0748.00

Genistein

CAS: 446-72-0

Genistein, the major phytoestrogen in soy, is linked to diminished female reproductive performance and to cancer chemoprevention and decreased adipose deposition; genistein-induces hypermethylation persisted into adulthood, decreases ectopic Agouti expression and protecting offspring from obesity, suggests that in utero dietary genistein affects gene expression and alters susceptibility to obesity in adulthood by permanently altering the epigenome.

Fórmula: C₁₅H₁₀O₅

Pureza: 95%~99%

Cor e Forma: Yellow powder

Peso molecular: 270.24

Ref: BP-BP0634

Genistein

CAS: 446-72-0

Fórmula: C₁₅H₁₀O₅

Peso molecular: 270.24

Ref: 4Z-G-033

Genistein

CAS: 446-72-0

Genistein

Pureza: >98%

Cor e Forma: Powder

Peso molecular: 270.24g/mol

Ref: 54-BIMB2006

Genistein

CAS: 446-72-0

Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.

Fórmula: C₁₅H₁₀O₅

Pureza: 98.22% - 99.64%

Cor e Forma: Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether Solid

Peso molecular: 270.24

Ref: TM-T1737

Genistein

CAS: 446-72-0

Oxygen-heterocyclic compound

Fórmula: C₁₅H₁₀O₅

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 270.24

Ref: 5G-89199

Genistein

Produto Controlado

CAS: 446-72-0

Stability Light Sensitive
Applications Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol
References Akiyama, T., et al.: J. Biol. Chem., 262, 5592 (1987), O'Dell, T.J., et al.: Nature, 353, 588 (1991), Aharonovits, O., et al.: Biochim Biophys. Acta, 1112, 181 (1992), Platanias, L.C., et al.: J. Biol. Chem., 267, 24053 (1992), Yoshida, H., et al.: Biochim. Biophys. Acta, 1137, 321 (1992), Uckun, F.M., et al.: Science, 267, 886 (1995), Merck Index 12th ed. 4395, Huang, R.Q.; Fang, M.J.; Dillon, G.H., Mol. Brain Res. 67: 177-183 (1999)

Fórmula: C₁₅H₁₀O₅

Cor e Forma: Light Yellow

Peso molecular: 270.24

Ref: TR-G350000

Genistein

CAS: 446-72-0

Genistein is a naturally occurring isoflavone, which is derived primarily from soy products and other legumes. Its chemical structure allows it to mimic the function of 17-beta-estradiol, a form of estrogen, by binding to estrogen receptors. This selective binding primarily targets estrogen receptor beta, leading to a range of biological effects. Moreover, Genistein exhibits antioxidant properties by scavenging free radicals and inhibiting oxidative stress.

Fórmula: C₁₅H₁₀O₅

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 270.24 g/mol

Ref: 3D-FG09961

Genistein

CAS: 446-72-0

M01798 - Genistein

Fórmula: C₁₅H₁₀O₅

Pureza: 97%

Cor e Forma: Solid, Light yellow powder

Peso molecular: 270.24

Ref: 10-M01798