CAS 4465-65-0

(1R,4aS,12aS)-3-[amino(hidroxi)metilideno]-4a,6,7-triidroxi-N,N,11-trimetil-2,4,5-trioxo-1,2,3,4,4a,5,12,12a-octahidrotetracen-1-amínio

Descrição:

A substância química com o nome "(1R,4aS,12aS)-3-[amino(hidroxi)metilideno]-4a,6,7-triidroxi-N,N,11-trimetil-2,4,5-trioxo-1,2,3,4,4a,5,12,12a-octahidrotetracen-1-amínio" e número CAS 4465-65-0 é um composto orgânico complexo caracterizado por sua intrincada estrutura policíclica e múltiplos grupos funcionais. Apresenta uma estrutura tetracíclica com vários grupos hidroxila (-OH) e amino (-NH2), contribuindo para sua potencial solubilidade em solventes polares e atividade biológica. A presença de grupos trioxo indica um alto grau de oxidação, o que pode influenciar sua reatividade e estabilidade. A estereoquímica específica, denotada pelas configurações R e S, sugere que o composto pode exibir propriedades quirais, potencialmente afetando suas interações em sistemas biológicos. Este composto pode ser de interesse na química medicinal devido à sua complexidade estrutural e à presença de grupos funcionais que poderiam participar de várias interações bioquímicas. No entanto, estudos detalhados seriam necessários para entender completamente suas propriedades, reatividade e potenciais aplicações.

Fórmula: C₂₂H₂₃N₂O₇

InChI: InChI=1/C22H22N2O7/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28/h4-6,11,16,25-26,30-31H,7,23H2,1-3H3/p+1/t11-,16+,22-/m0/s1

4-EPIANHYDROTETRACYCLINE HYDROCHLORIDE CRS

CAS: 4465-65-0

4-EPIANHYDROTETRACYCLINE HYDROCHLORIDE CRS

Fórmula: C₂₂H₂₃ClN₂O₇

Cor e Forma: Orange. Powder.

Peso molecular: 462.8802

Ref: 41-E0400000

4-Epianhydrotetracycline Hydrochloride

CAS: 4465-65-0

Tetracyclines and their derivatives; salts thereof

Fórmula: C₂₂H₂₂N₂O₇·HCl

Cor e Forma: Dark Yellow Brown Solid

Peso molecular: 426.1427

Ref: 45-1236506

4-Epianhydrotetracycline hydrochloride

CAS: 4465-65-0

EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.

Fórmula: C₂₂H₂₃ClN₂O₇

Cor e Forma: Solid

Peso molecular: 462.88

Ref: TM-T36599

4-Epianhydrotetracycline hydrochloride

Produto Controlado

CAS: 4465-65-0

Fórmula: C₂₂H₂₂N₂O₇·ClH

Cor e Forma: Neat

Peso molecular: 462.88

Ref: 04-C13174500

Tetracycline EP Impurity D HCl (Chlortetracycline EP Impurity I HCl , Lymecycline EP Impurity D HCl , 4-Epianhydrotetracycline HCl )

CAS: 4465-65-0

Fórmula: C₂₂H₂₂N₂O₇·HCl

Peso molecular: 426.43 36.46

Ref: 4Z-T-4035

4-Epianhydrotetracycline Hydrochloride Hydrate (>85%)

Produto Controlado

CAS: 4465-65-0

Applications An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study. This compound is a contaminant of emerging concern (CECs).
References Simmons, D., et al.: J. Pharm. Sci., 55, 1313 (1966), Paemen, L., et al.: Biochem. Pharmacol., 52, 105 (1996),

Fórmula: C₂₂H₂₂N₂O₇·HCl·H₂O

Pureza: >85%

Cor e Forma: Neat

Peso molecular: 462.88

Ref: TR-E578070

4-Epianhydrotetracycline hydrochloride

CAS: 4465-65-0

4-Epianhydrotetracycline hydrochloride is a chemically modified antibiotic derivative, originating from the structural transformation of tetracycline. It is derived through epimerization and dehydration processes, which alter the parent compound's structure.

Fórmula: C₂₂H₂₃ClN₂O₇

Pureza: Min. 95%

Peso molecular: 462.9 g/mol

Ref: 3D-EAA46565

Tetracycline EP Impurity D

CAS: 4465-65-0

Fórmula: C₂₂H₂₂N₂O₇HCl

Peso molecular: 426.4 : 36.46

Ref: ST-EA-CP-T200006

4-Epianhydrotetracycline hydrochloride hydrate

CAS: 4465-65-0, 7518-17-4

4-Epianhydrotetracycline hydrochloride hydrate is a chemical compound that inhibits the activation of protein kinase C (PKC) and blocks the apoptosis pathway. It has been shown to induce apoptosis in prostate cancer cells and also inhibits the proliferation of human microvessel endothelial cells. 4-Epianhydrotetracycline hydrochloride hydrate is stable in both human serum and wastewater, which makes it an ideal drug for treating many types of cancers. It is also used in pharmaceutical drugs as a cytochalasin, which are used to treat angina pectoris by reducing oxygen uptake by erythrocytes, thereby inhibiting oxidative phosphorylation. 4-Epianhydrotetracycline hydrochloride hydrate prevents mitochondrial cytochrome c release, thus blocking the apoptotic pathway in cells. This chemical compound may act as a regulatory molecule that affects energy metabolism and epidermal growth factor (EGF)

Fórmula: C₂₂H₂₃ClN₂O₇

Pureza: Min. 95%

Peso molecular: 462.88 g/mol

Ref: 3D-FE22716