CAS 4530-20-5

N-(tert-butiloxicarbonil)glicina

Descrição:

N-(tert-butiloxicarbonil)glicina, comumente referido como Boc-glicina, é um derivado de aminoácido caracterizado pela presença de um grupo protetor tert-butiloxicarbonila (Boc) ligado ao grupo amino da glicina. Este composto é tipicamente um sólido branco a off-white e é solúvel em solventes orgânicos polares, como metanol e dimetilsulfóxido (DMSO), mas menos solúvel em solventes não polares. O grupo Boc serve como uma parte protetora que estabiliza o grupo amino durante a síntese de peptídeos, permitindo reações seletivas sem interferir com a funcionalidade amino. A Boc-glicina é amplamente utilizada na síntese orgânica, particularmente na preparação de peptídeos e outras moléculas complexas. Sua estabilidade sob várias condições de reação a torna um intermediário valioso em aplicações farmacêuticas e bioquímicas. Além disso, pode ser desprotegida em condições ácidas suaves, regenerando o grupo amino livre para reações posteriores. No geral, a Boc-glicina é um composto essencial no campo da química orgânica sintética e da síntese de peptídeos.

Fórmula: C₇H₁₃NO₄

InChI: InChI=1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)

Chave InChI: InChIKey=VRPJIFMKZZEXLR-UHFFFAOYSA-N

SMILES: O(C(NCC(O)=O)=O)C(C)(C)C

Sinónimos:

• (tert-Butoxycarbonyl)aminoacetic acid
• (tert-Butoxycarbonyl)glycine
• 2-(tert-Butoxycarbonylamino)acetic acid
• 2-[(2-Methylpropan-2-yl)oxycarbonylamino]acetic acid
• Boc-<span class="text-smallcaps">L</span>-glycine
• Boc-Gly-OH
• Boc-Gly-OH~N-(tert-Butoxycarbonyl)glycine
• Glycine, N-[(1,1-dimethylethoxy)carbonyl]-
• Glycine, N-carboxy-, N-tert-butyl ester
• N-(terc-butoxicarbonil)glicina
• N-(tert-Butoxycarbonyl)glycin
• N-(tert-Butoxycarbonyl)glycine
• N-Boc-glycine
• N-[(1,1-Dimethylethoxy)carbonyl]glycine
• N-[(tert-Butyloxy)carbonyl]glycine
• N-[[(1,1-Dimethylethyl)oxy]carbonyl]glycine
• N-t-Butyloxycarbonylglycine
• N-tert-Butoxycarbonyl-2-aminoacetic acid
• N-tert-Butoxycarbonylglycine
• N^α-tert-Butyloxycarbonylglycine
• Nsc 127669
• NtertButoxycarbonylglycine
• Nα-tert-Butyloxycarbonylglycine
• [(Tert-Butoxycarbonyl)Amino]Acetate
• t-Butyloxycarbonylglycine

N-(tert-Butoxycarbonyl)glycine

CAS: 4530-20-5

Fórmula: C₇H₁₃NO₄

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 175.18

Ref: 3B-B1185

N-Boc-glycine, 98+%

CAS: 4530-20-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₇H₁₃NO₄

Pureza: 98+%

Cor e Forma: Crystals or powder or crystalline powder, White

Peso molecular: 175.18

Ref: 02-A11579

Boc-Gly-OH

CAS: 4530-20-5

M03287 - Boc-Gly-OH

Fórmula: C₇H₁₃NO₄

Pureza: 97%

Cor e Forma: Solid, Powder or Crystalline Powder

Peso molecular: 175.184

Ref: 10-M03287

Boc-Gly-OH

CAS: 4530-20-5

Bachem ID: 4001229.

Fórmula: C₇H₁₃NO₄

Pureza: > 99%

Cor e Forma: White

Peso molecular: 175.19

Ref: 01-4001229

Boc-Glycine

CAS: 4530-20-5

Fórmula: C₇H₁₃NO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 175.1824

Ref: IN-DA0034JU

[(t-Butoxycarbonyl)amino]acetic acid

CAS: 4530-20-5

[(t-Butoxycarbonyl)amino]acetic acid

Fórmula: C₇H₁₃NO₄

Pureza: 97%

Cor e Forma: white solid

Peso molecular: 175.18241g/mol

Ref: 54-OR323299

Boc-Gly-OH

CAS: 4530-20-5

Fórmula: (CH₃)₃COCONHCH₂CO₂H

Peso molecular: 175.18

Ref: 7W-GM7526

BOC-Glycine extrapure, 99%

CAS: 4530-20-5

Fórmula: C₇H₁₃NO₄

Pureza: min. 99%

Cor e Forma: White, Crystalline powder

Peso molecular: 175.20

Ref: SR-71943

N-Boc-glycine

Produto Controlado

CAS: 4530-20-5

Applications Used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents.
References Bajusz, S., et al.: J. Med. Chem., 33, 1729 (1990), Dahlgren, A., et al.: Bioorg. Med. Chem., 10, 1829 (2002),

Fórmula: C₇H₁₃NO₄

Cor e Forma: Neat

Peso molecular: 175.18

Ref: TR-B656125

Boc-Gly-OH

CAS: 4530-20-5

Boc-Gly-OH is a cyclic peptide with a fatty acid acyl chain. It is synthesized by reacting the amino acid glycine with sodium carbonate in the presence of trifluoroacetic acid to form the intermediate Boc-Gly-OSu. The product is then reacted with allyl bromide in a second step to produce Boc-Gly-OCH2CH2Br and then reacted with calcium chloride to yield the final product. Boc-Gly-OH has been used as an HIV inhibitor, which may be due to its ability to bind to both CD4 and gp120 proteins on the surface of HIV. This binding inhibits viral entry into host cells by blocking protease activity and fusion of viral envelope with host cell membrane, leading to inhibition of HIV infection.

Fórmula: C₇H₁₃NO₄

Pureza: Min. 95%

Peso molecular: 175.18 g/mol

Ref: 3D-BLG-2054

N-Boc-glycine

CAS: 4530-20-5

N-Boc-glycine is a chemical compound used in the synthesis of cyclic peptides. N-Boc-glycine is synthesized by the reaction of glycine with methanol and hydrochloric acid in the presence of an activated form of carbon monoxide. The pharmacokinetic properties of N-Boc-glycine are similar to those for human immunoglobulin, and it can be used as a reference compound for preparative high performance liquid chromatography (HPLC). It has been shown that the nitrogen atoms in N-Boc-glycine are chemically stable, which makes it suitable for asymmetric synthesis. N-Boc-glycine also has potent antagonist effects on biochemical properties such as calcium channel blockade, inhibition of platelet aggregation, and inhibition of neutrophil chemotaxis.

Fórmula: C₇H₁₃NO₄

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 175.18 g/mol

Ref: 3D-FB18945