CAS 457639-26-8

2,5-DiMethyl Celecoxib

CAS: 457639-26-8

Fórmula: C₁₈H₁₆F₃N₃O₂S

Pureza: 95%

Peso molecular: 395.3987

Ref: IN-DA00DFBY

2,5-dimethyl Celecoxib

CAS: 457639-26-8

2,5-dimethyl Celecoxib

Pureza: ≥98%

Peso molecular: 395.4g/mol

Ref: 54-BUP02361

2,5-Dimethylcelecoxib

Produto Controlado

CAS: 457639-26-8

Fórmula: C₁₈H₁₆F₃N₃O₂S

Cor e Forma: Neat

Peso molecular: 395.3987

Ref: 04-C12726320

2,5-Dimethyl-celecoxib

CAS: 457639-26-8

Fórmula: C₁₈H₁₆F₃N₃O₂S

Pureza: ≥ 99.0%

Cor e Forma: White to off-white solid

Peso molecular: 395.4

Ref: 7W-GL7510

2,5-dimethyl Celecoxib

CAS: 457639-26-8

2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.

Fórmula: C₁₈H₁₆F₃N₃O₂S

Pureza: 99.85%

Cor e Forma: Solid

Peso molecular: 395.4

Ref: TM-T35610

2,5-Dimethyl Celecoxib

Produto Controlado

CAS: 457639-26-8

Applications A non-cyclooxygenase-2 inhibitor analog of Celecoxib (C251000). The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib.
References Deckmann, K. et al.: Biochem. Pharmacol., 80, 1365 (2010); Virrey, J.J. et al.: Mol. Cancer. Therap., 9, 631 (2010); Chen, S. et al.: Leukemia Res., 34, 250 (2010);

Fórmula: C₁₈H₁₆F₃N₃O₂S

Cor e Forma: Neat

Peso molecular: 395.3987

Ref: TR-D470890

2,5-Dimethyl celecoxib

CAS: 457639-26-8

2,5-Dimethyl celecoxib is a potent inhibitor of the enzyme cyclooxygenase-2 (COX-2). It also inhibits autophagy, which is an intracellular process that degrades cellular components. 2,5-Dimethyl celecoxib has been shown to potently inhibit the production of PGE2 in mice with colon cancer and to induce apoptosis in human carcinoma cell lines by inhibiting the expression of survivin and MCL-1 proteins.

Fórmula: C₁₈H₁₆F₃N₃O₂S

Pureza: Min. 97 Area-%

Cor e Forma: White Powder

Peso molecular: 395.4 g/mol

Ref: 3D-FD22244

2,5-Dimethyl Celecoxib

CAS: 457639-26-8

Fórmula: C₁₈H₁₆F₃N₃O₂S

Peso molecular: 395.4

Ref: ST-EA-CP-C13030