CAS 481-42-5

Plumbagina

Descrição:

Plumbagina, com o número CAS 481-42-5, é um composto de naftoquinona que ocorre naturalmente, derivado principalmente das raízes da planta *Plumbago*, particularmente de *Plumbago zeylanica*. É caracterizado por sua aparência cristalina amarela a laranja e possui uma fórmula molecular de C11H8O3. Plumbagina exibe uma variedade de atividades biológicas, incluindo propriedades antimicrobianas, anticancerígenas e antioxidantes, tornando-o de interesse na pesquisa farmacológica. Sabe-se que o composto interage com várias vias celulares, potencialmente influenciando a apoptose e a proliferação celular. Além disso, Plumbagina tem sido estudado por sua capacidade de inibir certas enzimas e seu papel na medicina tradicional. Sua solubilidade é geralmente maior em solventes orgânicos do que em água, o que é uma característica comum de muitos compostos orgânicos. No entanto, devido à sua natureza reativa, Plumbagina pode sofrer oxidação e outras transformações químicas, o que pode afetar sua estabilidade e eficácia em várias aplicações. No geral, Plumbagina representa um composto significativo tanto na química de produtos naturais quanto na pesquisa medicinal.

Fórmula: C₁₁H₈O₃

InChI: InChI=1/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

Chave InChI: InChIKey=VCMMXZQDRFWYSE-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=C1C)=C(O)C=CC2

Sinónimos:

• 1,4-Naphthalenedione, 5-hydroxy-2-methyl-
• 1,4-Naphthoquinone, 5-hydroxy-2-methyl-
• 2-Methyl-5-hydroxy-1,4-naphthalenedione
• 2-Methyl-5-hydroxy-1,4-naphthoquinone
• 2-Methyljuglone
• 5-Hydroxy-2-Methylnaphthalene-1,4-Dione
• 5-Hydroxy-2-methyl-1,4-naphthalenedione
• 5-Hydroxy-2-methyl-1,4-naphthoquinone
• NSC 236613
• NSC 688284
• Plumbagin from Plumbago indica
• Plumbagin,95%
• Plumbagine
• Plumbagone
• Plumbagin
• Plumbagin, 99+%
• Ophioxylin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone, Plumbagin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone
• PLUMBAGIN(RG)
• PLUMBAGIN PRACTICAL GRADE
• SPECS AP-782/41885488
• RARECHEM BW GA 0426
• 5-hydroxy-2-methyl-4-naphthoquinone
• plumbapin
• 5-HYDROXY-2-METHYL-1,4-NAPTHOQUINONE
• Plumbagin (natural)
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene
• PLANT STEROLS KIT
• 5-hydroxy-2-methyl-4-naphthalenedione
• PLUMBAGIN FROM FROM PLUMBAGO INDICA
• PLUMBAGAN

Plumbagin

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: >98.0%(T)(HPLC)

Cor e Forma: Orange to Brown powder to crystal

Peso molecular: 188.18

Ref: 3B-P1139

Plumbagin

CAS: 481-42-5

Plumbagin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₁H₈O₃

Pureza: (HPLC) ≥90%

Cor e Forma: Powder

Peso molecular: 188.18

Ref: 11-0444

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 188.1794

Ref: IN-DA003TTF

Plumbagin

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Peso molecular: 188.18

Ref: 7W-GL1138

Plumbagin

CAS: 481-42-5

Plumbagin

Pureza: ≥98%

Peso molecular: 188.18g/mol

Ref: 54-BUP11118

plumbapin

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: 95%~99%

Peso molecular: 188.182

Ref: BP-BP1113

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

5-Hydroxy-2-methylnaphthalene-1,4-dione

Fórmula: C₁₁H₈O₃

Pureza: 95%

Cor e Forma: reddish orange/tan powder

Peso molecular: 188.18g/mol

Ref: 54-OR1174

Plumbagin

CAS: 481-42-5

Plumbagin, a yellow dye from naphthoquinone, is isolated from Plumbago and found in Drosera, Nepenthes, and black walnut drupe.

Fórmula: C₁₁H₈O₃

Pureza: 99.7% - 99.95%

Cor e Forma: Soild

Peso molecular: 188.18

Ref: TM-T2841

Plumbagin

CAS: 481-42-5

Plumbagin

Fórmula: C₁₁H₈O₃

Pureza: By hplc: 99.4% by area (210nm) (Typical Value in Batch COA)

Cor e Forma: reddish orange/tan powder

Peso molecular: 188.18g/mol

Ref: 54-BIDF1037

Plumbagin

CAS: 481-42-5

Quinone

Fórmula: C₁₁H₈O₃

Pureza: ≥ 98.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 188.18

Ref: 5G-80267

Plumbagin

CAS: 481-42-5

Applications Plumbagin induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Fórmula: C₁₁H₈O₃

Cor e Forma: Dark Orange

Peso molecular: 188.18

Ref: TR-P627000

Plumbagin

CAS: 481-42-5

Plumbagin is a quinonoid compound, which is a secondary metabolite found in the roots of Plumbago species. This compound is characterized by its naphthoquinone structure, which is responsible for its diverse biological activities. Plumbagin exerts its effects primarily through the generation of reactive oxygen species (ROS), modulation of cellular signaling pathways, and inhibition of specific enzyme functions, such as topoisomerases. These actions result in the modulation of cell proliferation, apoptosis, and inflammation, making Plumbagin a compound of interest for various biomedical applications.

Fórmula: C₁₁H₈O₃

Pureza: Min. 95%

Cor e Forma: Orange Powder

Peso molecular: 188.18 g/mol

Ref: 3D-FP13778

5-Hydroxy-2-methyl-[1,4]naphthoquinone

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: 98%

Cor e Forma: No data available.

Peso molecular: 188.182

Ref: 10-F032384

Plumbagin-d3

Produto Controlado

CAS: 481-42-5

Applications Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Fórmula: C₁₁H₅D₃O₃

Cor e Forma: Neat

Peso molecular: 191.2

Ref: TR-P627002