CAS 489-32-7
:Icariina
Descrição:
Icariina é um glicosídeo flavonoide derivado principalmente do gênero Epimedium, comumente conhecido como Erva de Cabra Apimentada. É reconhecido por suas potenciais propriedades farmacológicas, incluindo efeitos antioxidantes, anti-inflamatórios e neuroprotetores. Icariina exibe uma estrutura complexa caracterizada por um esqueleto de flavona com um moiety glicosídico, que contribui para sua atividade biológica. A substância é frequentemente estudada por seus potenciais benefícios em melhorar a saúde sexual e aumentar a densidade óssea, tornando-a de interesse na medicina tradicional e na pesquisa terapêutica moderna. Icariina é tipicamente encontrado em várias formas, incluindo pós e extratos, e é frequentemente utilizado em suplementos dietéticos. Sua solubilidade em solventes orgânicos e a solubilidade limitada em água podem influenciar sua biodisponibilidade e eficácia. Assim como muitos compostos naturais, os efeitos específicos e os mecanismos de ação de Icariina ainda estão sob investigação, e seu perfil de segurança é uma consideração importante para seu uso em produtos de saúde.
Fórmula:C33H40O15
InChI:InChI=1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
Chave InChI:InChIKey=TZJALUIVHRYQQB-XLRXWWTNSA-N
SMILES:C(C=C(C)C)C1=C2C(C(=O)C(O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)=C(O2)C4=CC=C(OC)C=C4)=C(O)C=C1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Sinónimos:- 2,6-anhydro-1-deoxy-7-O-[7-(beta-D-glucopyranosyloxy)-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-3-yl]-L-glycero-L-manno-heptitol
- 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 3-[(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)oxy]-7-(β-<smallcap>D</span>-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)oxy]-7-(β-<smallcap>D</span>-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)oxy]-7-(β-<smallcap>D</span>-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
- Epimedium
- Epimedium PE
- Epimedium extract
- Horny goat weed extract
- Icariine
- Icariln
- Ieariline
- Epimediun P.E.
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
- 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
- Ver mais sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
16 produtos.
Icariin
CAS:Fórmula:C33H40O15Pureza:>96.0%(HPLC)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:676.67Icariin, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Fórmula:C33H40O15Pureza:98%Cor e Forma:Pale yellow, PowderPeso molecular:676.67Icariin
CAS:Icariin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C33H40O15Pureza:(HPLC) ≥99%Cor e Forma:PowderPeso molecular:676.67Icariin
CAS:Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Icariin has been reported to have anti-hypoxic, phytoestrogenic, anti-osteoporotic, anti-inflammatory, neuroprotective, and anti-depressant-like activities. Icariin is effective in the attenuation of AHR and chronic airway inflammatory changes in OVA-induced murine asthma model, and this effect is associated with regulation of Th17/Treg responses. Icariin inhibited NF-κB signaling activation and the NLRP3-inflammasome/caspase-1/IL-1β axis.Fórmula:C33H40O15Pureza:95%~99%Peso molecular:676.668Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Fórmula:C33H40O15Pureza:97.82% - 98.3%Cor e Forma:SolidPeso molecular:676.66Icariin
CAS:Fórmula:C33H40O15Pureza:≥ 96.0%Cor e Forma:Pale yellow to yellow powderPeso molecular:676.66Icariin
CAS:Natural glycosideFórmula:C33H40O15Pureza:≥ 90.0 % (HPLC)Cor e Forma:PowderPeso molecular:676.67Icariin
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Icariin inhibits the ROS-dependent JNK and p38 pathways.<br>References Zhou, H., et al.: Exp. Ther. Med., 7, 1116 (2014)<br></p>Fórmula:C33H40O15Cor e Forma:NeatPeso molecular:676.66Icariin
CAS:<p>Icariin is a bioactive flavonoid compound, which is primarily derived from plants in the genus Epimedium, commonly known as Horny Goat Weed. This compound is a prenylated flavonol glycoside that is found in varying concentrations depending on the specific species of Epimedium used. Icariin exerts its effects through multiple biochemical pathways, most notably by inhibiting phosphodiesterase type 5 (PDE5), which leads to an increase in nitric oxide levels and the subsequent vasodilation of blood vessels.</p>Fórmula:C33H40O15Pureza:Min. 95%Cor e Forma:Slightly Yellow PowderPeso molecular:676.66 g/mol
