CAS 4940-37-8

Ethyl 4-(2-hydroxyphenyl)-2,4-dioxobutanoate

CAS: 4940-37-8

Fórmula: C₁₂H₁₂O₅

Pureza: 98%

Peso molecular: 236.2207

Ref: IN-DA01C3H8

Ethyl 4-(2-hydroxyphenyl)-2,4-dioxobutanoate

CAS: 4940-37-8

Ethyl 4-(2-hydroxyphenyl)-2,4-dioxobutanoate

Pureza: 98%

Peso molecular: 236.22g/mol

Ref: 54-OR1034113

ethyl 2-hydroxy-4-(2-hydroxyphenyl)-4-oxobut-2-enoate

CAS: 4940-37-8

Pureza: 98%

Peso molecular: 236.2230072

Ref: 10-F937911

Ethyl 4-(2-hydroxyphenyl)-2,4-dioxobutanoate

CAS: 4940-37-8

Sildenafil is a drug that is used for the treatment of erectile dysfunction. It belongs to the class of phosphodiesterase inhibitors and inhibits the enzyme phosphodiesterase type 5 (PDE-5). This enzyme functions to breakdown cyclic guanosine monophosphate (cGMP), which causes blood vessels in the penis to relax, leading to an erection. Sildenafil has been shown to be well tolerated with oral bioavailability of more than 70%. Sildenafil can be taken orally, but has also been studied for pulmonary administration. The pharmacokinetic properties of sildenafil have been optimized for oral administration in humans and it has been shown that sildenafil does not inhibit human liver cytochrome P450 enzymes. Sildenafil also shows inhibitory potency against other phosphodiesterases such as PDE-2, PDE-3, and PDE-6.

Fórmula: C₁₂H₁₂O₅

Pureza: Min. 95%

Peso molecular: 236.22 g/mol

Ref: 3D-EAA94037