CAS 49745-95-1

Cloridrato de dobutamina

Descrição:

Cloridrato de dobutamina é uma catecolamina sintética e um potente agente inotrópico usado principalmente no tratamento da insuficiência cardíaca e do choque cardiogênico. Atua principalmente nos receptores adrenérgicos beta-1, levando ao aumento da contratilidade miocárdica e à melhora do débito cardíaco sem aumentar significativamente a frequência cardíaca. A substância é tipicamente administrada por via intravenosa devido ao seu rápido início de ação e curta meia-vida. Cloridrato de dobutamina é um pó cristalino branco a off-white que é solúvel em água e tem um intervalo de pH que é geralmente neutro. Sua fórmula química é C18H23N3O3·HCl, e tem um peso molecular de aproximadamente 345,86 g/mol. O composto é frequentemente utilizado em ambientes clínicos para ecocardiografia de estresse e para gerenciar pacientes com insuficiência cardíaca aguda. Assim como qualquer medicamento, é essencial monitorar os pacientes quanto a possíveis efeitos colaterais, incluindo arritmias e hipotensão, durante sua administração.

Fórmula: C₁₈H₂₃NO₃·ClH

InChI: InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

Chave InChI: InChIKey=BQKADKWNRWCIJL-UHFFFAOYSA-N

SMILES: C(CNC(CCC1=CC=C(O)C=C1)C)C2=CC(O)=C(O)C=C2.Cl

Sinónimos:

• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride
• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (1:1)
• 4-(2-{[4-(4-Hydroxyphenyl)Butan-2-Yl]Amino}Ethyl)Benzene-1,2-Diol Hydrochloride (1:1)
• <span class="text-smallcaps">DL</span>-Dobutamine hydrochloride
• Benzene-1,2-Diol Hydrochloride
• Dobutamine Hydrochloride
• Dobutrex
• Inotrex
• NSC 299583
• dl-Dobutamine hydrochloride

Dobutamine Hydrochloride

CAS: 34368-04-2, 49745-95-1

Fórmula: C₁₈H₂₃NO₃·HCl

Pureza: >98.0%(HPLC)

Cor e Forma: White to Light yellow to Light orange powder to crystal

Peso molecular: 337.84

Ref: 3B-D4335

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride is a catecholamine that acts as a -adrenergic receptor agonist. It has its strongest effects on 1 receptors, with lesser but significant 2 receptor activation and only weak 1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic,

Fórmula: C₁₈H₂₄ClNO₃

Cor e Forma: Powder, White to off-white

Peso molecular: 337.84

Ref: 02-J61333

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Fórmula: C₁₈H₂₃NO₃ / C₁₈H₂₃NO₃HCl

Pureza: 89.1% / 99.9%

Cor e Forma: Off-White

Peso molecular: 301.16779

Ref: 47-674

DOBUTAMINE HYDROCHLORIDE CRS

CAS: 49745-95-1

DOBUTAMINE HYDROCHLORIDE CRS

Ref: 41-D2954000

Dobutamine Hydrochloride

CAS: 49745-95-1

Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof nesoi

Fórmula: C₁₈H₂₃NO₃·HCl

Cor e Forma: White Off-White Crystalline Powder

Peso molecular: 337.14447

Ref: 45-1224507

Dobutamine Hydrochloride

CAS: 49745-95-1

Dobutamine Hydrochloride

Pureza: 98%

Peso molecular: 337.84g/mol

Ref: 54-OR1024667

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Pureza: ≥95%

Peso molecular: 337.84g/mol

Ref: 54-BUP11279

Dobutamine hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₃NO₃HCl

Peso molecular: 337.85

Ref: 7W-GP1178

Dobutamine Hydrochloride

Produto Controlado

CAS: 49745-95-1

Fórmula: C₁₈H₂₃NO₃·ClH

Cor e Forma: Neat

Peso molecular: 337.84

Ref: 86-MM0675.00

Dobutamine hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₄ClNO₃

Pureza: 95%~99%

Peso molecular: 337.844

Ref: BP-BP4215

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.

Fórmula: C₁₈H₂₄ClNO₃

Pureza: 97.15% - 99.94%

Cor e Forma: Solid

Peso molecular: 337.84

Ref: TM-T8149

Dobutamine Hydrochloride RS

CAS: 49745-95-1

Cor e Forma: White To Very Pale Orange

Ref: 2K-1091000021

rac Dobutamine Hydrochloride

CAS: 49745-95-1

Stability Hygroscopic
Applications A sympathomimetic drug used to treat heart failure by inhibiting β1 receptors in the sympathetic nervous system. Cardiotonic.
References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Abdel F., et al.: J. Drug Res., 29, 83 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Fórmula: C₁₈H₂₃NO₃·ClH

Cor e Forma: Off-White

Peso molecular: 337.84

Ref: TR-D494445

Dobutamine Hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₃NO₃HCl

Peso molecular: 301.38 : 36.46

Ref: ST-EA-CP-D59000

4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride

CAS: 49745-95-1

Dobutamine is a beta-adrenergic agonist that causes the heart to contract and increase blood pressure. It is used for pharmacological treatment of congestive heart failure and ventricular arrhythmias, as well as during angiography of the coronary arteries. Dobutamine stimulates dopamine receptors in the heart, which increases the systolic pressure. Dobutamine has been shown to be effective in improving myocardial contractility, left ventricle function, and cardiac output in patients with chronic congestive heart failure. This drug also improves left ventricular regional wall motion, papillary muscle function, and mitral valve regurgitation. Dobutamine may cause side effects such as nausea, vomiting, headache, or chest pain.

Fórmula: C₁₈H₂₄ClNO₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 337.84 g/mol

Ref: 3D-FH27507

Dobutamine hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₄ClNO₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 337.84

Ref: 10-F240166