CAS 50-55-5

(-)-Reserpina

Descrição:

(-)-Reserpina é um alcaloide indólico derivado da planta Rauwolfia serpentina, comumente conhecido por seu uso na medicina tradicional e como agente antihipertensivo. É caracterizado por sua estrutura complexa, que inclui um núcleo tetracíclico e um grupo metóxi. O composto exibe um centro quiral, resultando em sua designação como "(-)-Reserpina," indicando sua forma enantiomérica específica. (-)-Reserpina funciona principalmente como um antagonista de monoaminas, influenciando os níveis de neurotransmissores no cérebro, particularmente inibindo a captação de norepinefrina e serotonina. Esse mecanismo contribui para seus efeitos sedativos e antihipertensivos. A substância é tipicamente administrada em sua forma de sal, como cloridrato de reserpina, e é conhecida por sua meia-vida relativamente longa. Além de suas aplicações terapêuticas, (-)-Reserpina tem sido estudado por seus potenciais efeitos em transtornos de saúde mental, embora seu uso tenha diminuído devido ao desenvolvimento de medicamentos mais novos com menos efeitos colaterais. As considerações de segurança incluem possíveis efeitos adversos, como sedação, distúrbios gastrointestinais e impactos cardiovasculares.

Fórmula: C₃₃H₄₀N₂O₉

InChI: InChI=1/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/p+1/t18-,22+,24-,27+,28+,31+/m1/s1

Chave InChI: InChIKey=QEVHRUUCFGRFIF-MDEJGZGSSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@@H]1OC)[H])[H])[H]

Sinónimos:

• (3Beta,16Beta,17Alpha,18Alpha,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
• (3Beta,16Beta,17Alpha,18Beta,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
• 11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
• 3,4,5-Trimethoxybenzoyl methyl reserpate
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate
• Anquil
• Apoplon
• Banasil
• Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
• Bioserpine
• Carpacil
• Crystoserpine
• Deserpine
• Elserpine
• Ent 50146
• Eserpine
• Eskaserp
• Hiposerpil
• Kitine
• Lemiserp
• Loweserp
• Mayserpine
• Methyl reserpate 3,4,5-trimethoxybenzoate (ester)
• Nsc 237659
• Nsc 59272
• Quiescin
• Rau-sed
• Raucap
• Raulen
• Raunervil
• Raupasil
• Raurine
• Rausedil
• Rausedyl
• Rausingle
• Rauwasedin
• Resercaps
• Resercen
• Reserlor
• Reserpamed
• Reserpex
• Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester)
• Reserpil
• Reserpin
• Reserpina
• Reserpine Crystalline
• Reserpine base
• Reserpine,98%
• Reserpoid
• Resine
• Resperine
• Respital
• Restran
• Riserpa
• Rivasin
• Roxinoid
• Sandril
• Sedaraupin
• Sedserp
• Serfin
• Serolfia
• Serp-AFD
• Serpaloid
• Serpanray
• Serpasil
• Serpasil Serpasol
• Serpasil premix
• Serpasol
• Serpate
• Serpen
• Serpentina
• Serpicon
• Serpiloid
• Serpine
• Serpine (pharmaceutical)
• Serpipur
• Sertabs
• Sertina
• T-Serp
• Temposerpine
• Triserpin
• Vio-Serpine
• Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3β,16β,17α,18β,20α)-
• NCI-C50157
• Anguil
• rauwita
• Ascoserpina
• imethoxy-,methylester,3,4,5-trimethoxybenzoate(ester)
• diutensen-r
• 3,20-YohiMban-16-carboxylic acid
• hydroserp
• gamma-Serpine
• serpasilpremix
• Carrserp
• reserpene
• Austrapine
• serpalan
• Rausan
• Helfoserpin
• rcrawastenumberu200
• Hypersine
• chloroserpin-250
• serpazol
• Reserpine (base and/or unspecified salts)
• demi-regroton
• Neoserp
• reser-ar
• Interpina
• RESERPINE(RG)
• YohiMban-16-carboxylicacid, 11,17-diMethoxy-18-[(3,4,5-triMethoxybenzoyl)oxy]-, Methyl ester, (3b,16b,17a,18b,20a)-
• (3β,16β,17α,18β,20α)-
• Purserpine
• Alserin
• 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-yohimban-16-carboxylicaci
• Rautrin
• salutensin
• rolserp
• trichlortensin
• Escaspere
• Alkarau
• Rauserpin-Alk
• oxy-methylester3,4,5-trimethoxybenzoate(ester)
• hydromox-r
• residine
• RESERPINE,USP
• chloroserp-500
• serpyrit
• Raugal
• chloroserpine-500
• reserp
• RESERPINE
• Enipresser
• RESERPINE,REAGENT
• Reserpine (200 mg)
• 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylicaci
• Raudixoid
• Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyl)oxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
• serpresan
• Rausedan
• serpone
• Reserpine Standard for LC-MS
• Benazyl
• rezide
• serpasil-apresoline
• reserpidefe
• component of Butiserpazide
• serathide
• METHYL RESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID ESTER
• METHYL RESERPATE
• R-e-s
• rivased
• Methyl reserpate 3,4,5-trimethyloxybenzoic acid
• hydrosine25
• reserfia
• klimanosid
• resedril
• serplexk
• Rauserpine
• Maviserpin
• Rauloydin
• renese-r
• diupres250
• rese-lar
• Carditivo
• serpivite
• Eskaserpine
• serpogen
• reserutin
• hydroserpineplus
• Broserpine
• Rauvlid
• banisil
• l-Carpserp
• mallopress
• ReserpineC33H40N209
• Eberpine
• hydro-reserpine-25
• serfolia
• chloroserp-250
• Eberspine
• metatensin#2
• tri-hydroserpine
• methylreserpate3,4,5-trimethoxybenzoicacid
• serpazil
• hydrochloride#2
• hydrochloride#1
• hydro-fluserpine#1
• recipin
• salutensin-demi
• Rauwipur
• serpazide
• resersana
• regroton
• hydropres50
• salazide-demi
• component of Regroton
• Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
• component of Renese R
• Rauserpol
• ReserpinePuriss
• reserpanca
• Key-serpine
• Reserpine bp
• Reserpine Vetec(TM) reagent grade
• diurese-r
• diupres500
• ser-a-gen
• reserpal
• ent50146
• Raupoid
• Reserpine, froM Rauvolfia
• Raunorine
• resomine
• (3beta,16beta,17alpha,18beta,20alpha)-methyleste
• hydropine
• hydroserpine#1
• metatensin#4
• RESERPINE BP/USP
• ,methylester,(3beta,16beta,17alpha,18beta,20alpha)-
• hydro-reserpine-50
• Raudiford
• resperin
• Idsoserp
• Rawilid
• Hiserpia
• hiposepil
• YohiMban-16-carboxylic acid
• Neo-antitensol
• RESERPINE, CRYSTALLIZED
• usafcb-27
• serpatone
• serpedin
• hydropres25
• salupres
• Rauwilid
• resiatric
• Neoserfin
• esidrix#2
• Reserbal
• Mephaserpin
• Reserpine,99%
• Hypersil
• reserpur
• hydroserpalan
• H 520
• Resedrex
• resaltex
• resocalm
• rezerpin
• Raumorine
• gilucard
• seominal
• 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-methyl ester 3,4,5-trimethoxybenzoate (ester)
• serpoid
• RESERPINE extrapure
• Rauwoleaf
• Reserjen
• (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylicacidmethylester

Reserpine

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow to Light orange powder to crystal

Peso molecular: 608.69

Ref: 3B-R0007

Reserpine, 99%

CAS: 50-55-5

Inhibits vesicular uptake of catecholamines and serotoninReserpine is an antipsychotic and antihypertensive drug used to treat the hypertension, strokes, heart attacks and kidney problems. It is used to treat the symptoms of dyskinesia in patients who are affected by huntington’s disease. It is wide

Fórmula: C₃₃H₄₀N₂O₉

Pureza: 99%

Cor e Forma: White to cream to yellow, Powder

Peso molecular: 608.69

Ref: 02-L03506

Reserpine

CAS: 50-55-5

Cor e Forma: Neat

Ref: 61-FOR1423.00

RESERPINE CRS

CAS: 50-55-5

RESERPINE CRS

Fórmula: C₃₃H₄₀N₂O₉

Cor e Forma: Crystalline Powder. White. Light Yellow. Small. Crystals. Powder.

Peso molecular: 608.6787

Ref: 41-R0200000

Reserpine

CAS: 50-55-5

Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi

Fórmula: C₃₃H₄₀N₂O₉

Cor e Forma: White Pale Yellow Crystalline Powder

Peso molecular: 608.27338

Ref: 45-1601000

Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester,(3b,16b,17a,18b,20a)-

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 608.6787

Ref: IN-DA00ILKE

Reserpine

CAS: 50-55-5

Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.

Fórmula: C₃₃H₄₀N₂O₉

Pureza: 98.85% - 99.81%

Cor e Forma: White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)

Peso molecular: 608.68

Ref: TM-T0791

Reserpine

CAS: 50-55-5

Reserpine

Pureza: 98%

Peso molecular: 608.68g/mol

Ref: 54-OR1030229

Reserpine

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Pureza: ≥ 98.0%

Cor e Forma: White to pale yellow or faint brown powder

Peso molecular: 608.69

Ref: 7W-GP9098

Reserpine

CAS: 50-55-5

Reserpine

Pureza: ≥98%

Peso molecular: 608.68g/mol

Ref: 54-BUP14755

Reserpine

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Cor e Forma: Off-White Solid

Peso molecular: 608.69

Ref: 4Z-R-123001

Reserpine

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Pureza: 95%~99%

Peso molecular: 608.688

Ref: BP-BP1203

Reserpine

Produto Controlado

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Cor e Forma: Neat

Peso molecular: 608.68

Ref: 04-C16809500

Reserpine

Produto Controlado

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Cor e Forma: Neat

Peso molecular: 608.68

Ref: 86-MM1423.00

Reserpine RS

CAS: 50-55-5

Cor e Forma: White To Pale Yellow

Ref: 2K-1184000021

Reserpine

CAS: 50-55-5

Natural alkaloid

Fórmula: C₃₃H₄₀N₂O₉

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 608.69

Ref: 5G-82642

Reserpine

Produto Controlado

CAS: 50-55-5

Applications An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.
References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),

Fórmula: C₃₃H₄₀N₂O₉

Cor e Forma: Off-White

Peso molecular: 608.68

Ref: TR-R144600

Reserpine - Bio-X ™

CAS: 50-55-5

Reserpine is an indole alkaloid that is found in the roots of the Rauwolfia plant. Reserpine has been shown to possess analgesic, anti-inflammatory, sedative, and anti-hypertensive properties. It is mainly used to treat mild to moderate hypertension. Reserpine inhibits the uptake of norepinephrine into storage vesicles by irreversibly blocking the vesicular monoamine transporter thus resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It is used as a pharmacological tool in research on chronic liver diseases.

Fórmula: C₃₃H₄₀N₂O₉

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 608.68 g/mol

Ref: 3D-BR164333

Reserpine

CAS: 50-55-5

VMAT monoamine transporter inhibitor; anti-hypertensive; anti-psychotic

Fórmula: C₃₃H₄₀N₂O₉

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 608.68 g/mol

Ref: 3D-FR09862

Reserpine extrapure, 99%

CAS: 50-55-5

Fórmula: C₃₃H₄₀N₂O₉

Pureza: min. 99%

Cor e Forma: White to pale yellow to pale beige to pale brown, Crystalline powder, Clear

Peso molecular: 608.69

Ref: SR-46861