CAS 500-62-9

Yangonina

Descrição:

Yangonina é um composto natural classificado como um derivado de benzopirano, encontrado principalmente na espécie vegetal *Piper methysticum*, comumente conhecida como kava. É reconhecido por suas propriedades psicoativas e tem sido estudado por seus potenciais efeitos terapêuticos, particularmente em relação à ansiedade e alívio do estresse. Yangonina exibe uma estrutura química única que contribui à sua atividade biológica, incluindo interações com o sistema endocanabinoide. O composto é conhecido por sua natureza lipofílica, que lhe permite atravessar facilmente as membranas biológicas. Em termos de solubilidade, Yangonina é geralmente solúvel em solventes orgânicos, mas tem solubilidade limitada em água. Seu perfil farmacológico sugere que pode influenciar sistemas de neurotransmissores, embora mais pesquisas sejam necessárias para elucidar completamente seus mecanismos de ação e potenciais benefícios à saúde. Assim como muitos produtos naturais, a segurança e eficácia de Yangonina em aplicações clínicas requerem consideração cuidadosa e investigação adicional.

Fórmula: C₁₅H₁₄O₄

InChI: InChI=1S/C15H14O4/c1-17-12-6-3-11(4-7-12)5-8-13-9-14(18-2)10-15(16)19-13/h3-10H,1-2H3/b8-5+

Chave InChI: InChIKey=XLHIYUYCSMZCCC-VMPITWQZSA-N

SMILES: C(=C/C1=CC=C(OC)C=C1)\C2=CC(OC)=CC(=O)O2

Sinónimos:

• (E)-4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 2H-Pyran-2-one, 4-methoxy-6-(p-methoxystyryl)-
• 2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-
• 2H-Pyran-2-one, 4-methoxy-6-[2-(4-methoxyphenyl)ethenyl]-, (E)-
• 2H-pyran-2-one, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-
• 4-Methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-on
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-one
• 4-Methoxy-6-[b-(p-anisyl)vinyl]-a-pyrone
• 4-Méthoxy-6-[(E)-2-(4-méthoxyphényl)éthènyl]-2H-pyran-2-one
• 5-Hydroxy-3-methoxy-7-(p-methoxyphenyl)-2,4,6-heptatrienoic Acid d-Lactone
• 6-(p-Methoxystyryl)-4-methoxy-a-pyrone

Yangonin

CAS: 500-62-9

Yangonin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₅H₁₄O₄

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 258.27

Ref: 11-4989

Yangonin

CAS: 500-62-9

Fórmula: C₁₅H₁₄O₄

Peso molecular: 258.27

Ref: 7W-GY4353

yangonin

CAS: 500-62-9

yangonin

Pureza: ≥98%

Peso molecular: 258.27g/mol

Ref: 54-BUP05071

Yangonin

CAS: 500-62-9

Fórmula: C₁₅H₁₄O₄

Pureza: 95%~99%

Peso molecular: 258.273

Ref: BP-BP1460

yangonin

CAS: 500-62-9

Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.

Fórmula: C₁₅H₁₄O₄

Pureza: 98.82% - 99.55%

Cor e Forma: Pale Yellow Powder

Peso molecular: 258.27

Ref: TM-T3S0738

Yangonin

CAS: 500-62-9

Fórmula: C₁₅H₁₄O₄

Peso molecular: 258.27

Ref: 4Z-Y-007001

Yangonin

CAS: 500-62-9

Lactone

Fórmula: C₁₅H₁₄O₄

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 258.27

Ref: 5G-89293

Yangonin

Produto Controlado

CAS: 500-62-9

Applications A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Fórmula: C₁₅H₁₄O₄

Cor e Forma: Neat

Peso molecular: 258.27

Ref: TR-Y100550

Yangonin

CAS: 500-62-9

Yangonin is a kavalactone, which is a type of compound found in the roots of the Piper methysticum plant, commonly known as kava. This product is derived through the extraction of kavalactones from the kava root, a process that isolates its active psychoactive components. Yangonin is known for its interaction with the brain's neuroreceptor systems, particularly the cannabinoid CB1 receptors. This interaction may contribute to its psychoactive effects, influencing mood and perception.

Fórmula: C₁₅H₁₄O₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 258.27 g/mol

Ref: 3D-FY137901

Yangonin-d3

Produto Controlado

CAS: 500-62-9

Applications Isotope labelled analog of Yangonin (Y100550), a lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Fórmula: C₁₅H₁₁D₃O₄

Cor e Forma: Neat

Peso molecular: 261.29

Ref: TR-Y100552