CAS 51-35-4

L-Hidroxiprolina

Descrição:

L-Hidroxiprolina é um aminoácido não proteogênico que é um derivado da prolina, caracterizado pela presença de um grupo hidroxila no anel de pirrolidina. É comumente encontrado no colágeno e desempenha um papel crucial na estabilização da estrutura de hélice tripla desta proteína, que é essencial para a integridade dos tecidos conectivos. L-Hidroxiprolina é um sólido cristalino branco que é solúvel em água e tem uma natureza levemente ácida devido à presença do grupo carboxila. Sua fórmula molecular é C5H9NO3, e tem um peso molecular de aproximadamente 131,13 g/mol. Este aminoácido é importante em vários processos bioquímicos, incluindo a síntese e o metabolismo do colágeno. Além disso, L-Hidroxiprolina é utilizado em pesquisas e aplicações farmacêuticas, particularmente em estudos relacionados à fibrose e à cicatrização de feridas. Suas propriedades estruturais únicas e sua importância biológica fazem dele um composto valioso nos campos científico e médico.

Fórmula: C₅H₉NO₃

InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1

Chave InChI: InChIKey=PMMYEEVYMWASQN-DMTCNVIQSA-N

SMILES: C(O)(=O)[C@@H]1C[C@@H](O)CN1

Sinónimos:

• (-)-4-Hydroxy-2-pyrrolidinecarboxylic acid
• (2S,4R)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid
• (2S,4R)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid
• (2S,4R)-4-Hydroxyproline
• (4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• (4R)-4-hydroxy-L-proline
• (4R,2S)-Hydroxyproline
• (R)-4-Hydroxy-(S)-proline
• (R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• (R)-4-Hydroxy-L-proline
• (S)-Hydroxyproline
• 1-Hydroxyproline
• 1-hydroxy-L-proline
• 3-hydroxy-L-proline
• 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic acid
• 4(R)-Hydroxyproline
• 4-Hydroxy-(S)-proline
• 4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• 4-Hydroxy-L-proline
• 4-Hydroxyproline
• 4-L-Hydroxyproline
• 4-hydroxy-L-proline (trans)
• 4-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline
• 4-trans-Hydroxy-L-proline
• <span class="text-smallcaps">L</span>-4-Hydroxyproline
• <span class="text-smallcaps">L</span>-Hydroxyproline
• <span class="text-smallcaps">L</span>-Hypro
• <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, (4R)-
• <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, trans-
• <span class="text-smallcaps">L</span>-trans-4-Hydroxyproline
• H-Hyp-OH
• Hydroxy-<span class="text-smallcaps">L</span>-proline
• Hydroxy-L-proline
• Hydroxyproline
• Hydroxyproline, L-
• Hypro
• L-4-Hydroxyprolin
• L-4-Hydroxyproline
• L-4-hidroxiprolina
• L-Hydroxyproline
• L-Hypro
• L-Proline, 4-hydroxy-, (4R)-
• L-Proline, 4-hydroxy-, trans-
• L-trans-4-Hydroxyproline
• L_s-Hydroxyproline
• Ls-Hydroxyproline
• Nsc 46704
• Proline, 4-hydroxy-
• Proline, 4-hydroxy-, <span class="text-smallcaps">L</span>-
• Proline, 4-hydroxy-, L-
• Trans-4-hydroxyl-L-proline
• delta-Hydroxyproline
• trans-(2S,4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• trans-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• trans-4-Hydroxyproline
• trans-<span class="text-smallcaps">L</span>-4-Hydroxyproline
• trans-<span class="text-smallcaps">L</span>-Hydroxyproline
• trans-L-4-Hydroxyproline
• trans-L-Hydroxyproline

trans-4-Hydroxy-L-proline

CAS: 51-35-4

Fórmula: C₅H₉NO₃

Pureza: >99.0%(T)(HPLC)

Cor e Forma: White powder to crystaline

Peso molecular: 131.13

Ref: 3B-H0296

trans-4-Hydroxy-L-proline, 99+%

CAS: 51-35-4

trans-4-Hydroxy-L-proline is used as a reagent for the preparation of neuroexcitatory kainoids and antifungal echinocandins. It is also involved in the synthesis of chiral ligands for enantioselective ethylation of aldehydes. This Thermo Scientific Chemicals brand product was originally part of the

Fórmula: C₅H₉NO₃

Pureza: 99+%

Cor e Forma: White to pale cream, Crystals or powder or crystalline powder

Peso molecular: 131.13

Ref: 02-A11851

H-Hyp-OH

CAS: 51-35-4

Kristensen et al. achieved the selective O-acylation of unprotected trans-hydroxyproline.

Fórmula: C₅H₉NO₃

Cor e Forma: White

Peso molecular: 131.13

Ref: 01-4002357

L-4-Hydroxyproline

CAS: 51-35-4

Fórmula: C₅H₉NO₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 131.1299

Ref: IN-DA0035PX

L-Hydroxyproline

CAS: 51-35-4

L-Hydroxyproline

Pureza: ≥98%

Peso molecular: 131.13g/mol

Ref: 54-BUP18166

trans-4-Hydroxy-L-proline, GlenCell™, suitable for cell culture

CAS: 51-35-4

Fórmula: C₅H₉NO₃

Pureza: (dried basis) 99.0 - 101.0 %

Cor e Forma: White crystalline powder

Peso molecular: 131.13

Ref: 7W-GM0902

trans-4-Hydroxy-L-Proline

CAS: 51-35-4

Fórmula: C₅H₉NO₃

Cor e Forma: White To Off-White Solid

Peso molecular: 131.13

Ref: 4Z-P-166019

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid

CAS: 51-35-4

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid

Fórmula: C₅H₉NO₃

Pureza: ≥95%

Cor e Forma: white crystals

Peso molecular: 131.12985g/mol

Ref: 54-OR6733

trans-4-Hydroxy-L-proline

CAS: 51-35-4

Fórmula: C₅H₉NO₃

Pureza: 98.5 - 101.5 %

Cor e Forma: White to off-white crystalline powder, or colourless crystals

Peso molecular: 131.13

Ref: 7W-GM7180

L-Hydroxyproline

CAS: 51-35-4

Fórmula: C₅H₉NO₃

Pureza: 95%~99%

Peso molecular: 131.131

Ref: BP-BP3523

L-Hydroxyproline

CAS: 51-35-4

L-Hydroxyproline (L-Hydroxyprolin) is one of the hydroxyproline (Hyp) isomers.

Fórmula: C₅H₉NO₃

Pureza: 99.77% - 99.92%

Cor e Forma: Solid

Peso molecular: 131.13

Ref: TM-T2A2476

trans-4-Hydroxy-L-proline

Produto Controlado

CAS: 51-35-4

Applications A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001);

Fórmula: C₅H₉NO₃

Cor e Forma: Neat

Peso molecular: 131.13

Ref: TR-H952376

trans-4-Hydroxy-L-proline

CAS: 51-35-4

Proline is a non-essential amino acid that is found in the basic structure of collagen. Proline has been shown to have physiological effects, including a protective effect on the myocardium, and can be used as an analytical method for detecting proline residues in biological samples. Trans-4-Hydroxy-L-proline is a proline derivative that has been shown to inhibit collagenase activity in vitro. It was also shown to have an optimum concentration of 1 mM and a matrix effect at pH 6.5. The model system used to study trans-4-hydroxy-l-proline was the enzyme extracted from rat liver.

Fórmula: C₅H₉NO₃

Cor e Forma: White Powder

Peso molecular: 131.13 g/mol

Ref: 3D-FH14370

H-Hyp-OH

CAS: 51-35-4

M03214 - H-Hyp-OH

Fórmula: C₅H₉NO₃

Pureza: 97%

Cor e Forma: Off-white crystalline powder

Peso molecular: 131.131

Ref: 10-M03214

L-Hydroxyproline extrapure CHR, 99%

CAS: 51-35-4

Fórmula: C₅H₉NO₃

Pureza: min. 99.0%

Cor e Forma: White to off white, Crystalline powder, Clear, Colourless to Pale yellow

Peso molecular: 131.13

Ref: SR-26921

trans-4-Hydroxy-L-proline-d6

Produto Controlado

CAS: 51-35-4

Fórmula: C₅D₆H₃NO₃

Cor e Forma: Neat

Peso molecular: 137.167

Ref: TR-H952374