CAS 51481-61-9
:Cimetidina
Descrição:
Cimetidina é um antagonista do receptor H2 da histamina, utilizado principalmente para reduzir a produção de ácido estomacal, sendo eficaz no tratamento de condições como úlceras pépticas, doença do refluxo gastroesofágico (DRGE) e síndrome de Zollinger-Ellison. Sua fórmula química é C10H13N5S, e apresenta um grupo tiourea, que é crucial para sua atividade farmacológica. Cimetidina é conhecido por sua capacidade de inibir a secreção de ácido gástrico ao bloquear a ação da histamina nos receptores H2 nas células parietais do revestimento do estômago. Além disso, tem uma meia-vida relativamente curta e é metabolizado no fígado, com algum potencial para interações medicamentosas devido ao seu efeito sobre as enzimas do citocromo P450. Efeitos colaterais comuns podem incluir tontura, dor de cabeça e distúrbios gastrointestinais. Cimetidina também é notável por seus efeitos antiandrogênicos, que podem levar à ginecomastia em alguns pacientes. No geral, continua sendo um medicamento significativo no manejo de distúrbios relacionados ao ácido, embora agentes mais novos com menos efeitos colaterais sejam frequentemente preferidos na prática clínica.
Fórmula:C10H16N6S
InChI:InChI=1/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
Chave InChI:InChIKey=AQIXAKUUQRKLND-UHFFFAOYSA-N
SMILES:C(SCCN=C(NC#N)NC)C1=C(C)N=CN1
Sinónimos:- 1-Cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
- 2-Cyano-1-Methyl-3-(2-(((5-Methylimidazol-4-Yl)Methyl)Thio)Ethyl)Guanidine
- Acibilin
- Acinil
- Biomet
- Cimal
- Cimetag
- Cimetidin
- Cimetidina
- Cimetidine (base or and unspecifieds salts)
- Cimetidine A
- Cimetidine AB
- Cimetum
- Dyspamet
- Edalene
- Eureceptor
- Fremet
- Gastromet
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-
- Histodil
- N-Cyano-N'-methyl-N''-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine
- N-Cyano-N′′-methyl-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
- Nsc 335308
- Peptol
- Skf 92334
- Tagamet
- Tagamet HB
- Tagamet HB 200
- Tamagret
- Tametin
- Tratul
- Ulcedin
- Ulcedine
- Ulcerex
- Ulcerfen
- Ulcimet
- Ulcofalk
- Ulcomedina
- Ulcomet
- Ulhys
- Cimetidine
- CIMETIDINE A TYPE
- FPF 1002
- N-CYANO-N'-METHYL-N''-[[2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]THIO]ETHYL]GUANIDINE
- CIMITIDINE
- ALTRAMET
- 2-CYANO-1-METHYL-3-[2-(5-METHYL-1H-IMIDAZOL-4-YL-METHYLTHIO)ETHYL]GUANIDINE
- Ver mais sinónimos
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23 produtos.
Cimetidine
CAS:Fórmula:C10H16N6SPureza:>99.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:252.34Cimetidine, 98+%
CAS:<p>Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the g</p>Fórmula:C10H16N6SPureza:98+%Cor e Forma:White to off-white, PowderPeso molecular:252.34Cimetidine
CAS:CimetidineFórmula:C10H16N6SPureza:99.6%Cor e Forma:White SolidPeso molecular:252.11572CIMETIDINE FOR PEAK IDENTIFICATION CRS
CAS:CIMETIDINE FOR PEAK IDENTIFICATION CRSFórmula:C10H16N6SPeso molecular:252.3392Cimetidine
CAS:Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoiFórmula:C10H16N6SCor e Forma:White Off-White Crystalline PowderPeso molecular:252.11572(Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
CAS:Fórmula:C10H16N6SPureza:98%Cor e Forma:SolidPeso molecular:252.3392Cimetidine
CAS:<p>Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS.</p>Fórmula:C10H16N6SPureza:99.82%Cor e Forma:Crystals Physical Description White Crystals With A Slight Sulfur-Mercaptan Odor (Ntp 1992)Peso molecular:252.34Cimetidine, USP grade
CAS:Fórmula:C10H16N6SPureza:≤ 0.2%Cor e Forma:White crystalline powderPeso molecular:252.34Cimetidine
CAS:Fórmula:C10H16N6SPureza:99.0 - 101.0 %Cor e Forma:White to off-white powderPeso molecular:252.34Cimetidine (Standard)
CAS:Cimetidine (Standard) is the standard substance of Cimetidine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.Fórmula:C10H16N6SPeso molecular:252.34Cimetidine 100 µg/mL in Acetonitrile
CAS:Fórmula:C10H16N6SCor e Forma:Single SolutionPeso molecular:252.34Cimetidine
CAS:<p>Cimetidine is a histamine-2 receptor antagonist that inhibits gastric acid secretion and reduces the activity of stomach enzymes. It is used to treat peptic ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Cimetidine has been shown to inhibit the activity of drug-metabolizing enzymes such as cytochrome P450. Cimetidine also inhibits the transport protein P-glycoprotein (P-gp), which leads to increased concentrations of some drugs in the blood and tissues. This inhibition may lead to an increase in cardiac effects with certain drugs, such as x-ray diffraction data with taxol or h1 antagonists.</p>Fórmula:C10H16N6SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:252.34 g/molN-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
CAS:Fórmula:C10H16N6SPureza:98%Cor e Forma:SolidPeso molecular:252.34
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