CAS 52-67-5

(-)-Penicilamina

Descrição:

(-)-Penicilamina é um agente quelante e um derivado da penicilina, utilizado principalmente no tratamento de condições como artrite reumatoide e doença de Wilson, onde ajuda a remover o excesso de cobre do corpo. É um aminoácido com um grupo tiol, que lhe permite formar complexos com íons metálicos, aumentando seus efeitos terapêuticos. A substância é caracterizada por sua natureza quiral, existindo como um único enantiômero, que é a forma biologicamente ativa. (-)-Penicilamina é tipicamente administrado por via oral e é conhecido por sua capacidade de se ligar a metais pesados, facilitando sua excreção. Tem uma solubilidade relativamente baixa em água e é sensível à luz e ao ar, necessitando de condições adequadas de armazenamento. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais e reações cutâneas, e seu uso requer monitoramento devido à potencial toxicidade e interações com outros medicamentos. No geral, (-)-Penicilamina desempenha um papel significativo no manejo de condições médicas específicas através de suas propriedades químicas únicas.

Fórmula: C₅H₁₁NO₂S

InChI: InChI=1/C5H11NO2S/c1-6(2)4(3-9)5(7)8/h4,9H,3H2,1-2H3,(H,7,8)

Chave InChI: InChIKey=VVNCNSJFMMFHPL-VKHMYHEASA-N

SMILES: [C@@H](C(C)(C)S)(C(O)=O)N

Sinónimos:

• (-)-Penicillamine
• (2S)-2-Azaniumyl-3-methyl-3-sulfanylbutanoate
• (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
• (S)-3,3-Dimethylcysteine
• (S)-Penicillamine
• 2-Amino-3-mercapto-3-methylbutanoic acid
• 3,3-Dimethyl-D-cysteine
• 3-Mercapto-<span class="text-smallcaps">D</span>-valine
• 3-Mercapto-D-valine
• <span class="text-smallcaps">D</span>-(-)-Penicillamine
• <span class="text-smallcaps">D</span>-3-Mercaptovaline
• <span class="text-smallcaps">D</span>-Mercaptovaline
• <span class="text-smallcaps">D</span>-Penamine
• <span class="text-smallcaps">D</span>-Valine, 3-mercapto-
• Artamin
• Cuprenil
• Cuprimine
• Cupripen
• D-3-Mercaptovaline
• D-Mercaptovaline
• D-Penamine
• D-Penicillin
• D-Valine, 3-mercapto-
• D-minus-penicillamine free base
• DPA
• Depamine
• Depen
• Dimethylcysteine
• H-D-Pen-OH
• Kuprenil
• Mercaptyl
• Metalcaptase
• N,N-dimethylcysteine
• Nsc 81549
• Pendramine
• Penicilamina
• Penicillamin
• Penicillamine, D-(-)-
• Penicilllamine
• Perdolat
• Reduced <span class="text-smallcaps">D</span>-penicillamine
• Reduced D-penicillamine
• Reduced penicillamine
• Sufirtan
• Trolovol
• Valine, 3-mercapto-, <span class="text-smallcaps">D</span>-
• Valine, 3-mercapto-, D-
• β-Thiovaline
• D-(-)-Penicillamine
• D-Penicillamine
• 3-mercapto-d-valin
• D(-)-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID
• DISTAMINE
• (S)-2-AMINO-3-MERCAPTO-3-METHYL-BUTYRIC ACID
• alpha-amino-beta-methyl-beta-mercaptobutyricacid
• D-BETA,BETA-DIMETHYLCYSTEINE
• (S)-Penicillamin
• D[-]-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID
• 3-Sulfanylvaline
• D-BETA-MERCAPTOVALINE

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 149.21

Ref: 3B-P0147

D-(-)-Penicillamine, 98%

CAS: 52-67-5

It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It  is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages,

Fórmula: C₅H₁₁NO₂S

Pureza: 98%

Cor e Forma: Powder, White to pale cream

Peso molecular: 149.21

Ref: 02-A11446

PENICILLAMINE CRS

CAS: 52-67-5

PENICILLAMINE CRS

Fórmula: C₅H₇NO₃

Cor e Forma: Powder

Peso molecular: 129.114

Ref: 41-P0310000

Penicillamine

CAS: 52-67-5

Thioglycolic acid and mercaptocarboxylic acids

Fórmula: C₅H₁₁NO₂S

Cor e Forma: White Off-White Powder

Peso molecular: 149.21 g/mol

Ref: 45-1501006

Penicillamine

CAS: 52-67-5

Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper

Fórmula: C₅H₁₁NO₂S

Pureza: 99.69% - 99.8%

Cor e Forma: Fine White Or Practically White Crystalline Powder Solid

Peso molecular: 149.21

Ref: TM-T0983

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 149.2113

Ref: IN-DA0038OE

D-Penicillamine, Ph. Eur. grade

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: ≤ 0.1%

Cor e Forma: White or almost white crystalline powder

Peso molecular: 149.21

Ref: 7W-GA1554

Penicillamine

CAS: 52-67-5

Penicillamine

Pureza: ≥98%

Peso molecular: 149.21g/mol

Ref: 54-BUP19801

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: 98.0 - 101.0 % (dried basis)

Cor e Forma: White to off-white powder

Peso molecular: 149.21

Ref: 7W-GA2413

3-Thio-D-valine

CAS: 52-67-5

3-Thio-D-valine

Fórmula: C₅H₁₁NO₂S

Pureza: 98%

Cor e Forma: white solid

Peso molecular: 149.21g/mol

Ref: 54-OR18365

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Peso molecular: 149.21

Ref: 4Z-P-891

D-Penicillamine, USP grade

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: 97.0 - 102.0 %

Cor e Forma: White to off-white powder or solid

Peso molecular: 149.21

Ref: 7W-GA5612

D-Penicillamine

CAS: 52-67-5

Applications A Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010); Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010);

Fórmula: C₅H₁₁NO₂S

Cor e Forma: Neat

Peso molecular: 149.21

Ref: TR-P223000

D-Penicillamine-d6

Produto Controlado

CAS: 52-67-5

Applications D-Penicillamine-d6 is the isotope labelled analog of D-Penicillamine which is a Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010), Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010),

Fórmula: C₅D₆H₅NO₂S

Cor e Forma: Neat

Peso molecular: 155.248

Ref: TR-P223002

H-D-Pen-OH

CAS: 52-67-5

M06142 - H-D-Pen-OH

Fórmula: C₅H₁₁NO₂S

Pureza: 95%

Cor e Forma: Solid, White to off-white crystalline powder

Peso molecular: 149.21

Ref: 10-M06142

D-Penicillamine-d6 (Racemic)

Produto Controlado

CAS: 1795786-79-6, 2714436-24-3, 52-67-5

Fórmula: C₅H₅D₆NO₂S

Cor e Forma: Neat

Peso molecular: 155.25

Ref: TR-P223006

D-Penicillamine

CAS: 52-67-5

D-Penicillamine is a nonsteroidal anti-inflammatory drug that is used to treat bowel disease, including ulcerative colitis and Crohn's disease. It has also been used as a treatment for schizophrenia that is unresponsive to other treatments. D-Penicillamine binds covalently to reactive oxygen species (ROS), thereby preventing their interaction with proteins and DNA. The binding of ROS by D-penicillamine can be monitored using electrochemical impedance spectroscopy (EIS). The compound has also been shown to reduce the expression of bcl-2 protein in human cells, which may result in increased oxidative injury and rates of cell proliferation. D-Penicillamine has been shown to have therapeutic benefits for patients with primary sclerosing cholangitis, myocardial infarcts, or preparative high performance liquid chromatography (HPLC) analysis.

Fórmula: C₅H₁₁NO₂S

Pureza: Min 97%

Cor e Forma: White Powder

Peso molecular: 149.21 g/mol

Ref: 3D-FP26792