CAS 520-36-5

Apigenina

Descrição:

Apigenina é um flavonoide que ocorre naturalmente em várias plantas, particularmente em frutas, vegetais e ervas como salsa, camomila e aipo. Sua fórmula química é C15H10O5, e apresenta uma estrutura de flavona caracterizada por uma espinha dorsal de cromona com grupos hidroxila em posições específicas. Apigenina é conhecido por seus potenciais benefícios à saúde, incluindo propriedades anti-inflamatórias, antioxidantes e anticancerígenas. Apresenta uma aparência cristalina amarela e é solúvel em solventes orgânicos como etanol e dimetilsulfóxido, mas tem solubilidade limitada em água. Apigenina interage com várias vias biológicas, influenciando a sinalização celular e a expressão gênica, o que contribui para seu potencial terapêutico. Além disso, foi estudado por seus efeitos sobre a ansiedade e o sono, tornando-se um assunto de interesse tanto na pesquisa nutricional quanto farmacêutica. Seu perfil de segurança é geralmente favorável, mas mais estudos são necessários para entender completamente seus mecanismos e eficácia em aplicações clínicas.

Fórmula: C₁₅H₁₀O₅

InChI: InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H

Chave InChI: InChIKey=KZNIFHPLKGYRTM-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC(=C1)C3=CC=C(O)C=C3)=CC(O)=CC2O

Sinónimos:

• 4',5,7-Trihydroxyflavone
• 4′,5,7-Trihydroxyflavone
• 5,7,4'-Trihydroxyflavone
• 5,7-Dihidroxi-2-(4-Hidroxifenil)-4-Benzopirona
• 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Benzopyrone
• 5,7-Dihydroxy-2-(4-Hydroxyphenyl)chromen-4-one
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyron
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• 5,7-Dihydroxy-2-p-hydroxyphenyl-4-chromenone
• Apegenin
• Apigenin
• Apigenine
• Apigenol
• Chamomile
• Flavone, 4',5,7-trihydroxy-
• Flavone, 4′,5,7-trihydroxy-
• Ly 080400
• Nsc 83244
• Pelargidenon 1449
• St 056301
• Uccf 031
• Versulin
• 75580
• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
• C.I. Natural Yellow 1

Apigenin

CAS: 520-36-5

Fórmula: C₁₅H₁₀O₅

Pureza: >98.0%(HPLC)

Cor e Forma: Light yellow to Brown powder to crystal

Peso molecular: 270.24

Ref: 3B-A1514

Apigenin

CAS: 520-36-5

Apigenin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₁₅H₁₀O₅

Pureza: (HPLC) ≥99%

Cor e Forma: Powder

Peso molecular: 270.25

Ref: 11-1102S

Apigenin (5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone)

CAS: 520-36-5

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Fórmula: C₁₅H₁₀O₅

Cor e Forma: Off-White Light Brown Yellow Powder

Peso molecular: 270.05282

Ref: 45-1040683

Apigenin

CAS: 520-36-5

Fórmula: C₁₅H₁₀O₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 270.2369

Ref: IN-DA0034H3

Apigenin

CAS: 520-36-5

Apigenin

Fórmula: C₁₅H₁₀O₅

Pureza: 97%

Cor e Forma: light beige solid

Peso molecular: 270.24g/mol

Ref: 54-BIK9018

Apigenin

CAS: 520-36-5

Fórmula: C₁₅H₁₀O₅

Pureza: ≥ 98.0% (anhydrous basis)

Cor e Forma: Yellow or brown powder

Peso molecular: 270.24

Ref: 7W-GP1532

Apigenin

CAS: 520-36-5

Apigenin

Pureza: ≥95%

Peso molecular: 270.24g/mol

Ref: 54-BUP17818

Apigenin

CAS: 520-36-5

Apigenin, a naturally occurring plant flavone (4', 5, 7,-trihydroxyflavone) abundantly present in common fruits and vegetables including parsley, onions, oranges, tea, chamomile, wheat sprouts and some seasonings, has been shown to possess remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties.

Fórmula: C₁₅H₁₀O₅

Pureza: 95%~99%

Cor e Forma: Yellow powder

Peso molecular: 270.24

Ref: BP-BP0177

Apigenin

CAS: 520-36-5

Fórmula: C₁₅H₁₀O₅

Cor e Forma: Neat

Peso molecular: 270.24

Ref: 04-C10290600

Apigenin

CAS: 520-36-5

Fórmula: C₁₅H₁₀O₅

Peso molecular: 270.24

Ref: 4Z-A-746

Apigenin

CAS: 520-36-5

Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.

Fórmula: C₁₅H₁₀O₅

Pureza: 97.64% - 99.66%

Cor e Forma: Yellow Needles From Aqueous Pyridine Solid

Peso molecular: 270.24

Ref: TM-T2175

Apigenin

CAS: 520-36-5

Apigenin

Fórmula: C₁₅H₁₀O₅

Pureza: 97%

Cor e Forma: faint beige powder

Peso molecular: 270.24g/mol

Ref: 54-OR7265T

Apigenin

CAS: 520-36-5

Oxygen-heterocyclic compound

Fórmula: C₁₅H₁₀O₅

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 270.24

Ref: 5G-89159

Apigenin

Produto Controlado

CAS: 520-36-5

Applications Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.uv(max)ethanol: 269, 340 nm (e= 18,800, 20,900) moderately sol. in hot alcohol
References Chaumontet, C., et al.: Carcinogenesis, 15, 2325 (1994); Sato, F., et al.: Biochem. Biophys. Res. Commun., 204, 578 (1994); Kuo, M.L. et al.: Biochem. Biophys. Res. Commun., 212, 767 (1995);

Fórmula: C₁₅H₁₀O₅

Cor e Forma: Yellow To Brown

Peso molecular: 270.24

Ref: TR-A726500

Apigenin - 97%

CAS: 520-36-5

Apigenin - 97% is a high-purity flavonoid compound, which is primarily derived from various plant sources such as parsley, chamomile, and celery. This compound is known for its significant presence in the plant kingdom, where it functions as a secondary metabolite contributing to plant defense.

Fórmula: C₁₅H₁₀O₅

Pureza: Min. 97 Area-%

Cor e Forma: Powder

Peso molecular: 270.24 g/mol

Ref: 3D-FA16099

Apigenin - 94%

CAS: 520-36-5

Apigenin - 94% is a purified form of apigenin, which is a naturally occurring flavonoid. It is primarily sourced from various plant species, including parsley, celery, and chamomile, where it is a prominent active component. The mode of action of apigenin involves multiple biochemical pathways: it acts as an anti-inflammatory agent, modulates enzyme activities, and exhibits antioxidant properties by scavenging free radicals. Additionally, apigenin interacts with cellular signaling pathways, such as the MAPK and PI3K/Akt, which contribute to its protective effects against oxidative stress and its potential in promoting apoptosis in cancerous cells.

Fórmula: C₁₅H₁₀O₅

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 270.24 g/mol

Ref: 3D-FA159894

4,5,7-Trihydroxyflavone

CAS: 520-36-5

M01289 - 4,5,7-Trihydroxyflavone

Fórmula: C₁₅H₁₀O₅

Pureza: 95%

Cor e Forma: Solid, Light yellow powder

Peso molecular: 270.24

Ref: 10-M01289

4',5,7-Trihydroxyflavone, 97%

CAS: 520-36-5

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication. This Thermo Scientif

Fórmula: C₁₅H₁₀O₅

Pureza: 97%

Cor e Forma: Cream to yellow to brown, Powder

Peso molecular: 270.24

Ref: 02-L15041

Apigenin 100 µg/mL in Acetonitrile:Methanol

Produto Controlado

CAS: 520-36-5

Fórmula: C₁₅H₁₀O₅

Cor e Forma: Single Solution

Peso molecular: 270.24

Ref: 04-A10290600MC-100