CAS 52299-14-6
:Succinil-L-alanil-L-alanil-L-alanina p-nitroanilida
Descrição:
Succinil-L-alanil-L-alanil-L-alanina p-nitroanilida é um substrato de peptídeo sintético comumente utilizado em ensaios bioquímicos, particularmente para a detecção de enzimas proteolíticas, como as serina proteases. Este composto apresenta um grupo succinilo, que melhora sua solubilidade e estabilidade, e um grupo p-nitroanilida que serve como um indicador cromogênico. Após a clivagem enzimática, a liberação de p-nitroanilina resulta em uma mudança de cor mensurável, permitindo a quantificação da atividade enzimática. A estrutura consiste em uma sequência de aminoácidos, especificamente resíduos de L-alanina, que contribuem para sua especificidade e interação com as enzimas-alvo. O composto é tipicamente solúvel em soluções aquosas e exibe estabilidade sob condições laboratoriais padrão. Seu uso em aplicações de pesquisa e diagnóstico destaca sua importância na compreensão da cinética enzimática e das interações proteicas. Assim como com muitos substratos peptídicos, deve-se ter cuidado com as condições de armazenamento e manuseio para manter sua integridade e reatividade.
Fórmula:C19H25N5O8
InChI:InChI=1S/C19H25N5O8/c1-10(20-15(25)8-9-16(26)27)17(28)21-11(2)18(29)22-12(3)19(30)23-13-4-6-14(7-5-13)24(31)32/h4-7,10-12H,8-9H2,1-3H3,(H,20,25)(H,21,28)(H,22,29)(H,23,30)(H,26,27)/t10-,11-,12-/m0/s1
Chave InChI:InChIKey=GVUGADOWXGKRAE-SRVKXCTJSA-N
SMILES:N(C([C@@H](NC([C@@H](NC([C@@H](NC(CCC(O)=O)=O)C)=O)C)=O)C)=O)C1=CC=C(N(=O)=O)C=C1
Sinónimos:- 3-Carboxypropionyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
- 43: PN: CN101457218 PAGE: 2 claimed protein
- <span class="text-smallcaps">L</smallcap>-Alaninamide, N-(3-carboxy-1-oxopropyl)-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanyl-N-(4-nitrophenyl)-
- Chromozym ELA
- N-(3-Carboxy-1-oxopropyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-N-(4-nitrophenyl)-<smallcap>L</span>-alaninamide
- N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-L-alaninamide
- N-SUCCINYL-(L-ALA)3-p-NITROANILIDE **03-32-0009**
- N-Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
- N-Succinyl-Ala-Ala-Ala-p-nitroanilide
- Suc-Ala-Ala-Ala-pNA
- Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine 4-nitroanilide
- Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
- Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanyl p-nitroanilide
- Succinyl-<span class="text-smallcaps">L</span>-trialanine p-nitroanilide
- N-Succinyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide
- 3-Carboxypropionyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide
- L-Alaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-
- Succinyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide
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Ordenar por
Pureza (%)
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100
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50
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90
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95
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100
9 produtos.
Suc-Ala-Ala-Ala-pNA
CAS:Suc-AAA-pNA, a readily soluble and sensitive substrate for human and rat neutrophil and porcine pancreatic elastases. The trialanine substrate is also hydrolyzed by proteinase K, subtilisins and thermitase as well as by astacin, a crayfish zinc-endopeptidase.Fórmula:C19H25N5O8Pureza:> 99%Cor e Forma:Light YellowPeso molecular:451.44Suc-AAA-pNA
CAS:<p>Suc-AAA-pNA is a synthetic peptide substrate commonly used for protease activity assays and widely applied in biochemical experiments.</p>Fórmula:C19H25N5O8Pureza:99.75%Cor e Forma:SolidPeso molecular:451.43N-Succinyl-Ala-Ala-Ala-p-Nitroanilide
CAS:N-Succinyl-Ala-Ala-Ala-p-NitroanilidePureza:98%Peso molecular:451.43g/molN-Succinyl-L-alanyl-L-alanyl-L-alanine 4-nitroanilide
CAS:<p>N-Succinyl-L-alanyl-L-alanyl-L-alanine 4 nitroanilide is a synthetic substrate that has been shown to have proteolytic activity against dextran sulfate, collagen, and sephadex g-100. It also has insecticidal activity in that it inhibits the development of larvae of the insect Drosophila melanogaster. NSLAAALAALAAN can be used as a chemotactic agent for tissue culture cells. This synthetic substrate was also found to have antiinflammatory properties and may be useful in treating chronic bronchitis or other metabolic disorders.</p>Fórmula:C19H25N5O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:451.43 g/molSuc-Ala-Ala-Ala-pNA
CAS:<p>Suc-Ala-Ala-Ala-pNA is a protease inhibitor that is used in the treatment of metabolic disorders. It has been shown to have neurotrophic effects, which may be due to its ability to inhibit the activity of proteases, such as cathepsin B and proteinase 3. Suc-Ala-Ala-Ala-pNA has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the activity of proinflammatory cytokines such as interleukin 1β, tumor necrosis factor α, and prostaglandin E2. Suc-Ala-Ala-Ala-pNA has long term efficacy in treating neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.</p>Fórmula:C19H25N5O8Pureza:Min. 95%Peso molecular:451.43 g/molSuc-Ala-Ala-Ala-pNA
CAS:<p>Suc-Ala-Ala-Ala-pNA is a peptide that binds to the acetylcholine receptor and activates it. This peptide has been shown to have potential as a research tool for studying the pharmacology of acetylcholine receptors in vitro. It has also been used as an inhibitor of neuronal ion channels, such as potassium channels, that are involved in the transmission of nerve impulses. Suc-Ala-Ala-Ala-pNA is not suitable for use in humans because it would be broken down by proteases before it could reach its target, but this peptide has applications in cell biology and neuroscience.</p>Fórmula:C19H25N5O8Pureza:Min. 95%Peso molecular:451.43 g/mol
