CAS 534-64-5

Pyridinium, 1-[(4-amino-2-metil-5-pirimidinil)metil]-3-(2-hidroxietil)-2-metil-, brometo, hidrobrometo (1:1:1)

Descrição:

Pyridinium, 1-[(4-amino-2-metil-5-pirimidinil)metil]-3-(2-hidroxietil)-2-metil-, brometo, hidrobrometo (1:1:1), comumente referido pelo seu número CAS 534-64-5, é um composto de amônio quaternário caracterizado por sua estrutura de piridínio, que inclui um grupo de pirimidina. Este composto normalmente exibe propriedades como solubilidade em água e solventes orgânicos polares devido à sua natureza iônica, atribuída à presença de íons brometo. É frequentemente utilizado em aplicações bioquímicas e farmacêuticas, particularmente como um reagente ou na formulação de medicamentos devido à sua capacidade de interagir com sistemas biológicos. A presença de grupos funcionais amino e hidroxila sugere potencial para ligações de hidrogênio, influenciando sua reatividade e interação com outras moléculas. Além disso, a estrutura do composto pode conferir atividades biológicas específicas, tornando-o de interesse na química medicinal. Dados de segurança devem ser consultados para manuseio e uso, uma vez que compostos de amônio quaternário podem apresentar graus variados de toxicidade e impacto ambiental.

Fórmula: C₁₄H₂₀Br₂N₄O

InChI: InChI=1/C14H19N4O.2BrH/c1-10-12(5-7-19)4-3-6-18(10)9-13-8-16-11(2)17-14(13)15;;/h3-4,6,8,19H,5,7,9H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

Chave InChI: InChIKey=DMVBWVASDWGFNH-UHFFFAOYSA-M

SMILES: C([N+]=1C(C)=C(CCO)C=CC1)C=2C(N)=NC(C)=NC2.[Br-].Br

Sinónimos:

• 1-(4-Ammonio-2-Methylpyrimidin-5-Yl)-3-(2-Hydroxyethyl)-2-Methylpyridinium Dibromide
• 1-[(4-Amino-2-Methylpyrimidin-5-Yl)Methyl]-3-(2-Hydroxyethyl)-2-Methylpyridinium Bromide Hydrobromide (1:1:1)
• 2-Picolinium, 1-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-hydroxyethyl)-, bromide, monohydrobromide
• Neopyrithiamine
• Pyridinium, 1-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-hydroxyethyl)-2-methyl-, bromide, hydrobromide (1:1:1)
• Pyridinium, 1-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-hydroxyethyl)-2-methyl-, bromide, monohydrobromide
• Pyrithiamin
• Pyrithiamin hydrobromide
• Pyrithiamine
• Pyrithiamine bromide hydrobromide
• 1-([4-amino-2-methyl]-5-pyrimidylmethyl)-2-methyl-3-(β-hydroxyethyl)pyridinium bromide
• Neopyrithiaminehydrobromideappox.
• NEOPYRITHIAMINE HYDROBROMIDE
• PyrithiaMine hydrobroMide ~95%, crystalline
• 2-[1-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-2-methyl-pyridin-1-ium-3-yl]ethanol bromide hydrobromide
• PYRITHIAMINE HYDROBROMIDE
• 1-[(4-AMino-2-Methyl-5-pyriMidinyl)Methyl]-3-(2-hydroxyethyl)-2-MethylpyridiniuM BroMide HydrobroMide
• Pyrithiamine hydrobromide,1-([4-Amino-2-methyl]-5-pyrimidylmethyl)-2-methyl-3-(β-hydroxyethyl)pyridinium bromide, Neopyrithiamine
• 1-[(4-AMINO-2-METHYL)-5-PYRIMIDYLMETHYL]-2-METHYL-3-[BETA-HYDROXYETHYL]-PYRIDINIUM BROMIDE HYDROBROMIDE
• 2-[1-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium-3-yl]ethanol bromide hydrobromide
• 2-[1-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-methyl-pyridin-1-ium-3-yl]ethanol bromide hydrobromide

Pyrithiamine

CAS: 534-64-5

Fórmula: C₁₄H₂₀Br₂N₄O

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 420.1428

Ref: IN-DA003U30

Pyrithiamine (hydrobromide)

CAS: 534-64-5

Pyrithiamine (hydrobromide)

Pureza: 95%

Peso molecular: 420.14g/mol

Ref: 54-OR1035351

Pyrithiamine HBr

CAS: 534-64-5

Fórmula: C₁₄H₁₉N₄O·Br·HBr

Peso molecular: 259.33 79.90 80.91

Ref: 4Z-T-8460

Pyrithiamine

Produto Controlado

CAS: 534-64-5

Applications Thiamine (T344185) antagonist. Thiamine (T344185) analog.
References Cooper, J., et al.: J. Neurochem., 19, 1809 (1972), Patrini, C., et al.: Brain Res., 628, 179 (1993), Nauti, A., et al.: Metab. Brain Dis., 12, 145 (1997),

Fórmula: C₁₄H₁₉N₄O·HBr·Br

Cor e Forma: Light Yellow To Light Beige

Peso molecular: 420.14

Ref: TR-P997415

Pyrithiamine Hydrobromide

CAS: 534-64-5

Fórmula: C₁₄H₁₉N₄OBrHBr

Peso molecular: 259.33 : 79.90 : 80.91

Ref: ST-EA-CP-T2039

Pyrithiamine hydrobromide

CAS: 534-64-5

Pyrithiamine hydrobromide, an inhibitor of thiamine metabolism substrate for thiamine pyrophosphate kinase, causes neurologic symptoms wernickke - korsakoff .

Fórmula: C₁₄H₂₀Br₂N₄O

Cor e Forma: Solid

Peso molecular: 420.14

Ref: TM-T36947

Pyrithiamine

CAS: 534-64-5

Pyrithiamine is an antimicrobial agent that inhibits the growth of bacteria by disrupting the disulfide bond between two cysteine residues. It has been shown to inhibit the formation of bacterial spores, which are resistant to many antibiotics. Pyrithiamine also has antioxidant properties and can reduce oxidative stress in neurons, leading to neuronal death. This drug also has a strong effect on energy metabolism and may be used as a treatment for mitochondrial diseases.

Fórmula: C₁₄H₂₀Br₂N₄O

Pureza: Min. 95%

Peso molecular: 420.14 g/mol

Ref: 3D-FP27348