CAS 5355-48-6
:Card-20(22)-enolídeo, 3-[(O-4-O-acetil-2,6-didesoxi-β-d-ribo-hexopiranosil-(1→4)-O-2,6-didesoxi-β-d-ribo-hexopiranosil-(1→4)-2,6-didesoxi-β-d-ribo-hexopiranosil)oxi]-12,14-diidroxi-, (3β,5β,12β)-
Descrição:
Card-20(22)-enolídeo, com o número CAS 5355-48-6, é um composto orgânico complexo que pertence à classe dos cardenolídeos, que são glicosídeos esteroides. Esta substância apresenta uma estrutura esteroide com múltiplos grupos hidroxila, especificamente nas posições 12 e 14, contribuindo para sua atividade biológica. A presença de uma estrutura glicosídica única, consistindo em três unidades de dideoxi-β-D-ribo-hexopiranosídeo ligadas por ligações (1→4), aumenta sua solubilidade e potenciais interações com sistemas biológicos. O grupo acetila na posição 4 da primeira unidade de açúcar modifica ainda mais suas propriedades, podendo influenciar sua farmacocinética e bioatividade. Os cardenolídeos são conhecidos por seus efeitos na função cardíaca, frequentemente utilizados em aplicações medicinais, particularmente no tratamento de condições cardíacas. A estereoquímica específica indicada pela configuração (3β,5β,12β) é crucial para sua atividade biológica, pois determina a interação do composto com alvos celulares. No geral, Card-20(22)-enolídeo exemplifica a intrincada relação entre estrutura e função em produtos naturais bioativos.
Fórmula:C43H66O15
InChI:InChI=1/C43H66O15/c1-20-38(55-23(4)44)30(45)17-36(53-20)57-40-22(3)54-37(18-32(40)47)58-39-21(2)52-35(16-31(39)46)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(48)42(6)27(10-12-43(28,42)50)24-13-34(49)51-19-24/h13,20-22,25-33,35-40,45-48,50H,7-12,14-19H2,1-6H3
Chave InChI:InChIKey=NREAGDHHMSOWKZ-DXJNJSHLSA-N
SMILES:O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5C[C@H](O)[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](OC(C)=O)[C@@H](C)O7)[C@@H](C)O6)[C@@H](C)O5)CC4)[H])(C[C@@H](O)[C@]1(C)[C@H](CC2)C=8COC(=O)C8)[H])[H]
Sinónimos:- (3β,5β,12β)-3-[(O-4-O-Acetyl-2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
- 16'-Acetyldigoxin
- 3-{[4-O-acetyl-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
- 4'''-Acetyldigoxin
- Acetyl-digoxin-beta
- Card-20(22)-enolide, 3-((O-4-O-acetyl-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1.4)-O-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1.4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
- Card-20(22)-enolide, 3-[(O-4-O-acetyl-2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
- Cardioreg
- Cor-Puren
- Digorid B
- Digotab
- Digoxigenin + zuckerkette wie bei acetyl-digitoxin-alpha
- Digoxigenin + zuckerkette wie bei acetyl-digitoxin-alpha [German]
- Digoxigenin tridigitoxoside-β-acetate
- Digoxin Didier
- Digoxin, 4'''-acetate (8CI)
- Digoxin, 4′′′-acetate
- Digoxin, acetate, beta-
- Hexamethyleneimine 3,5-dinitrobenzoate
- Kardiamed
- Longdigox
- Novodigal
- Stillacor
- beta-Acetyldigoxin
- β-Acetodigoxin
- β-Acetyldigoxin
- Card-20(22)-enolide, 3-[(O-4-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
- (3β,5β,12β)-3-[(O-4-O-Acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
- hexamethyleneimine3,5-dinitrobenzoate
- ACETYLDIGOXIN, B-
- -acetyldigoxin for peak identification CRS
- β-Acetyl Digoxin
- -Acetyldigoxin CRS
- BETA-ACETYLDIGOXIN USP/EP/BP
- 2-Acetyl Digoxin
- Acetyldigoxin research grade
- Digoxin Impurity 10(Digoxin EP Impurity J)
- 3β-[[4-O-[4-O-(4-O-Acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)-2,6-dideoxy-β-D-ribo-hexopyranosyl]-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy]-12β,14-dihydroxy-5β-card-20(22)-enolide
- 3β-[4-O-[4-O-(4-O-Acetyl 2,6-dideoxy-β-D-ribo-hexopyranosyl)-2,6-dideoxy-β-D-ribo-hexopyranosyl]-2,6-dideoxy-β-D-ribo-hexopyranosyloxy]-12β,14-dihydroxy-5β,14β-carda-20(22)-enolide
- digoxigenin+zuckerkettewiebeiacetyl-digitoxin-alpha
- (3β,5β,12β)-3-[(O-4-O-Αcetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
- digoridb
- Digoxin IMpurity J
- Digoxin EP Impurity J
- Ver mais sinónimos
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Pureza (%)
0
100
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0
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50
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90
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95
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100
7 produtos.
β-ACETYLDIGOXIN FOR PEAK IDENTIFICATION CRS
CAS:β-ACETYLDIGOXIN FOR PEAK IDENTIFICATION CRSFórmula:C43H66O15Peso molecular:822.9751β-ACETYLDIGOXIN CRS
CAS:β-ACETYLDIGOXIN CRSFórmula:C43H66O15Cor e Forma:White.Peso molecular:822.9751β-Acetyldigoxin
CAS:β-Acetyldigoxin is a cardiac glycoside, which is a naturally derived chemical compound primarily sourced from Digitalis lanata, a species of the foxglove plant. These compounds exert their effects by inhibiting the Na+/K+-ATPase enzyme, leading to an increase in intracellular calcium concentrations. This mechanism enhances myocardial contractility, contributing to its positive inotropic effects, which are essential in treating heart-related ailments.
Fórmula:C43H66O15Pureza:Min. 95%Peso molecular:822.98 g/molBeta-Acetyl Digoxin
CAS:Produto ControladoApplications Digoxin derivative, a cardiotonic glycosides steroid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yoshida, F., et al.: J. Med. Chem., 43, 2575 ( 2000), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Wang, J., et al.: Anal. Chim. Acta, 601, 156 (2007),Fórmula:C43H66O15Cor e Forma:NeatPeso molecular:822.98
