CAS 54-35-3

Penicilina G procaína

Descrição:

Penicilina G procaína, com o número CAS 54-35-3, é um antibiótico semissintético que combina penicilina G com procaína para melhorar suas propriedades farmacológicas. Este composto é caracterizado por sua atividade antibacteriana de amplo espectro, principalmente eficaz contra bactérias gram-positivas e alguns organismos gram-negativos. É tipicamente administrado por injeção intramuscular devido à sua baixa biodisponibilidade oral. O componente de procaína serve para prolongar a ação da penicilina G, retardando sua liberação na corrente sanguínea, permitindo assim efeitos terapêuticos prolongados. Penicilina G procaína é comumente utilizado no tratamento de várias infecções bacterianas, incluindo infecções do trato respiratório, infecções de pele e certos tipos de sífilis. Sua formulação é projetada para minimizar o risco de reações alérgicas associadas à penicilina, embora a hipersensibilidade ainda possa ocorrer em alguns indivíduos. Assim como outros antibióticos da penicilina, atua inibindo a síntese da parede celular bacteriana, levando à lise e morte celular. O armazenamento e manuseio adequados são essenciais para manter sua eficácia, pois é sensível ao calor e à umidade.

Fórmula: C₁₆H₁₈N₂O₄S·C₁₃H₂₀N₂O₂

InChI: InChI=1S/C16H18N2O4S.C13H20N2O2/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);5-8H,3-4,9-10,14H2,1-2H3/t11-,12+,14-;/m1./s1

Chave InChI: InChIKey=WHRVRSCEWKLAHX-LQDWTQKMSA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(CC3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H].C(OCCN(CC)CC)(=O)C1=CC=C(N)C=C1

Sinónimos:

• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid-2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid-2-(diethylamino)ethyl 4-aminobenzoate hydrate (1:1:1)
• 3,3-Dimethyl-7-Oxo-6-[(Phenylacetyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid-2-(Diethylamino)Ethyl 4-Aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-, compd. with 2-(diethylamino)ethyl p-aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-[2S-(2α,5α,6β)]-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• Abbocillin DC
• Afsillin
• Ampin-penicillin
• Aquacilina
• Aquacillin
• Aquasuspen
• Avloprocil
• Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, mono[(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, mono[[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• Benzylpenicillin
• Benzylpenicillin Procaine
• Benzylpenicillin novocaine salt
• Benzylpenicillin procaine salt
• Carepen
• Cilicaine
• Crysticillin
• Depocillin
• Despacilina
• Distaquaine
• Dorsallin AR
• Duphapen
• Duracillin
• Ethacilin
• Flo-Cillin Aqueous
• Geepenil
• Hostacillin
• Hydracillin
• Ilcocillin P
• Jenacillin O
• Kabipenin
• Ledercillin
• Lenticillin
• Mammacillin
• Masticillin
• Megapen
• Micro-Pen
• Millicillin
• Mylipen
• Neoproc
• Nopcaine
• Novocaine penicillin
• Pen 50
• Pen-Fifty
• Penaquacaine G
• Penicillin G Procaine Sterile
• Penicillin G procaine
• Penicillin procaine
• Penovet
• Pentaquacaine G
• Penzal N 300
• Premocillin
• Pro-Pen
• Procain Penicillin G
• Procaine Benzylpenicillin
• Procaine benzylpenicillin salt
• Procaine benzylpenicillinate
• Procaine penicillin (G)
• Procanodia
• Prostabillin
• Retardillin
• Sharcillin
• Vetspen
• Vitablend
• Wycillin
• Sterile Penicillin G Procaine/SodiuM3∶1 API
• Benzylpenicillinic acid, procaine
• Penicillin G procaine Benzylpenicillin procaine API
• Procaine penicillin G(fortified) USP/EP/BP
• BENZYLPENICILLIN PROCAIN SALT
• PROCAINE BENZYLPENICILLIN (PROCAINE PENICILLIN) ASSAY STANDARD BP(CRM STANDARD)
• PENICILLIN-G PROCAIN SALT
• Penicillin G Procaine/Sodium 3:1 USP/EP/BP
• PROCAINE BENZYLPENICILLIN EPP(CRM STANDARD)
• Procaine penicillin G(1% lecithin/citrate acid)
• 4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(phenylacetyl)amino- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenylethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• Penicillin G procaine +1% lecithin CP200/BP/USP/EP
• Procain-Penicillin
• PENICILLIN G PROCAINE USP/EP/BP
• Penicillin G procaine sterile CP200/BP/USP/EP
• Procaine penicillin G USP/EP/BP
• BENZYLPENICILLIN PROCAINE + POTASSIC 3:1

Procaine benzylpenicillin

CAS: 54-35-3

Procaine benzylpenicillin

Fórmula: C₁₃H₂₀N₂O₂ / C₁₃H₂₀N₂O₂C₁₆H₁₈N₂O₄SH₂O

Cor e Forma: White Powder

Peso molecular: 236.15248

Ref: 47-295

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 2-(diethylamino)ethyl 4-aminobenzoate

CAS: 54-35-3

Fórmula: C₂₉H₃₈N₄O₆S

Pureza: 98%

Peso molecular: 570.7002

Ref: IN-DA00I9MZ

Procaine penicillin G

CAS: 54-35-3

Procaine penicillin G

Pureza: ≥98%

Peso molecular: 570.7g/mol

Ref: 54-BUP14921

Procaine penicillin G

CAS: 54-35-3

Procaine penicillin G treats syphilis, anthrax, oral infections, pneumonia, diphtheria, cellulitis, and bites.

Fórmula: C₂₉H₃₈N₄O₆S

Pureza: 99.73%

Cor e Forma: A White Crystalline Powder

Peso molecular: 570.7

Ref: TM-T4553

Penicillin G procaine

Produto Controlado

CAS: 54-35-3

Penicillin G procaine is a form of penicillin that is commonly used to treat bacterial infections. It is a prodrug that undergoes hydrolysis in the body to release penicillin, its active form. Penicillin G procaine has been shown to be effective against Streptococcus pyogenes, which causes streptococcal pharyngitis, and other bacteria that are sensitive to penicillin. Penicillin G procaine is less toxic than other forms of penicillin and has minimal side effects. The pharmacological effects of the drug are due primarily to the inhibition of bacterial cell wall synthesis by binding to peptidoglycan precursors and blocking their cross-linking. The concentration–time curve for penicillin G procaine shows that it has a long half-life in humans, making it suitable for continuous treatment in patients with chronic infections.

Fórmula: C₁₆H₁₈N₂O₄S·C₁₃H₂₀N₂O₂

Pureza: Min. 95%

Peso molecular: 570.7 g/mol

Ref: 3D-FP33385