CAS 5490-27-7
:Sulfato de diidroestreptomicina
Descrição:
Sulfato de diidroestreptomicina é um antibiótico aminoglicosídeo derivado de Streptomyces griseus, usado principalmente para tratar infecções bacterianas, particularmente aquelas causadas por Mycobacterium tuberculosis. É caracterizado por sua capacidade de inibir a síntese de proteínas bacterianas ao se ligar à subunidade ribossômica 30S, levando à leitura incorreta do mRNA e, em última análise, à morte celular bacteriana. O composto é tipicamente administrado por injeção devido à sua baixa biodisponibilidade oral. Sulfato de diidroestreptomicina é solúvel em água, o que facilita seu uso em ambientes clínicos. Sua estrutura química inclui múltiplos grupos amino, contribuindo para sua basicidade e interação com ribossomos bacterianos. Embora seja eficaz contra uma variedade de bactérias Gram-negativas e algumas Gram-positivas, é importante monitorar os possíveis efeitos colaterais, incluindo nefrotoxicidade e ototoxicidade, que são preocupações comuns com os aminoglicosídeos. Assim como com todos os antibióticos, testes de suscetibilidade adequados são recomendados para garantir a eficácia contra patógenos específicos.
Fórmula:C21H41N7O12H2O4S
InChI:InChI=1S/C21H41N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1
Chave InChI:InChIKey=GSPKOIJAMLDYCY-RMIBZTJPSA-N
SMILES:S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(CO)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3
Sinónimos:- 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (1:1)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N<sup>1</sup>,N<sup>3</sup>-bis(aminoiminomethyl)-, sulfate (2:3)
- Didromycin
- Didromycine
- Dihydroestreptomycin Sulphate
- Dihydrostereptomycin Sulfate
- Dihydrostreptomycin 3/2 sulfate
- Dihydrostreptomycin Suflate
- Dihydrostreptomycin Sulfate(2:3)
- Dihydrostreptomycin sesqui-Sulfate
- Dihydrostreptomycin sesquisulfate
- Dihydrostreptomycin sulfate
- Double-mycin
- N'',N'''''-[(1S,2S,3R,4S,5S,6R)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl)-α-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3) (salt)
- Panstreptin
- Sol-Mycin
- Streptomagna
- Streptomycin, dihydro-, sulfate (2:3) (salt)
- D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)
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95
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10 produtos.
DIHYDROSTREPTOMYCIN SULFATE CRS
CAS:DIHYDROSTREPTOMYCIN SULFATE CRSFórmula:C21H43N7O16SPeso molecular:681.6684Dihydrostreptomycin Sulfate
CAS:Dihydrostreptomycin and its derivatives; salts thereofFórmula:(C21H41N7O12)2·3H2SO4Cor e Forma:White PowderPeso molecular:1166.56264Dihydrostreptomycin Sulfate
CAS:Fórmula:C21H41N7O12·3H2O4SCor e Forma:White To Off-White SolidPeso molecular:2 583.60 3 98.08Dihydrostreptomycin sesquisulfate
CAS:Fórmula:C21H41N7O121·5H2SO4Pureza:≥ 730IU/mg (anhydrous)Cor e Forma:White to off-white powderPeso molecular:730.71Dihydrostreptomycin sesquisulfate
CAS:Produto ControladoFórmula:C21H41N7O12H2O4SCor e Forma:NeatPeso molecular:1461.42Dihydrostreptomycin sesquisulfate 100 µg/mL in Acetonitrile/Water
CAS:Fórmula:C21H41N7O12H2O4SCor e Forma:Single SolutionPeso molecular:1461.42Dihydrostreptomycin sulfate
CAS:Dihydrostreptomycin sulfate (Dihydrostreptomycin sesquisulfate) inhibits protein synthesis by binding to the 30S ribosomal subunit.Fórmula:C21H41N7O12·5H2SO4Pureza:97.38% - 99.9%Cor e Forma:SolidPeso molecular:730.71Dihydrostreptomycin Sesquisulfate
CAS:Stability Hygroscopic
Applications A derivative of Streptomycin (S687500) with antimicrobial activity. It is used in veterinary medicine to treat bovine infection and also as an effective antibiotic to control pests found in crops.
References Gradin, J.L. et al.: J. Am. Vet. Med. Assoc., 183, 434 (1983); Bishop, J.R. et al.: J. Dairy Sci., 67, 437 (1984); Singh, D.R. et al.: Obi. Chik. Daig. Gak. Ken. Hok., 11, 475 (1979);Fórmula:C21H41N7O12·3H2O4SCor e Forma:Off-WhitePeso molecular:1461.42Dihydrostreptomycin sesquisulfate, EP
CAS:Dihydrostreptomycin sesquisulfate, EP is an aminoglycoside antibiotic, structurally derived from Streptomyces griseus. This compound originates from microbial biosynthesis, a method which harnesses the natural antibiotic-producing capabilities of microbial cultures. The mode of action of dihydrostreptomycin sesquisulfate involves binding to the 30S subunit of bacterial ribosomes, which interrupts the process of protein synthesis, ultimately leading to bacterial cell death.
Fórmula:C21H41N7O12•(H2SO4)1Pureza:(Hplc) 94.0 To 102.0%Cor e Forma:PowderPeso molecular:1,461.42 g/molDihydrostreptomycin sesquisulfate
CAS:Dihydrostreptomycin sesquisulfate is an aminoglycoside antibiotic, which is derived from the bacterium Streptomyces griseus. Its mode of action involves binding to the 30S subunit of the bacterial ribosome, leading to the disruption of protein synthesis. This binding interferes with the initiation complex formation, causing misreading of mRNA and ultimately inhibiting bacterial growth.Fórmula:C21H41N7O12•(H2SO4)1Pureza:Min. 95%Peso molecular:730.71 g/mol
