CAS 55869-99-3

Anisodamina

Descrição:

Anisodamina, com o número CAS 55869-99-3, é um composto químico que pertence à classe dos alcaloides tropânicos. É derivado principalmente da planta Anisodus tanguticus e exibe propriedades anticolinérgicas, o que significa que pode inibir a ação da acetilcolina nos receptores muscarínicos. Essa característica torna Anisodamina útil em várias aplicações médicas, particularmente no tratamento de condições como bradicardia e certos tipos de choque. O composto é conhecido por sua capacidade de induzir vasodilatação e melhorar a circulação sanguínea, o que pode ser benéfico no manejo de problemas cardiovasculares. Anisodamina também possui potenciais efeitos neuroprotetores e pode ser explorado por seu papel no tratamento de distúrbios neurológicos. Sua estrutura química apresenta um anel tropânico, que é típico de muitos alcaloides, contribuindo para sua atividade biológica. Assim como muitos agentes farmacológicos, o perfil de segurança, a dosagem e os potenciais efeitos colaterais de Anisodamina devem ser cuidadosamente considerados em ambientes clínicos.

Fórmula: C₁₇H₂₃NO₄

InChI: InChI=1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13-,14+,15+,16-/m0/s1

Chave InChI: InChIKey=WTQYWNWRJNXDEG-RBZJEDDUSA-N

SMILES: CN1[C@]2([C@@H](O)C[C@@]1(C[C@H](OC([C@H](CO)C3=CC=CC=C3)=O)C2)[H])[H]

Sinónimos:

• (-)-(3S,6S,2′S)-6β-Hydroxyhyoscyamine
• (-)-6β-Hydroxyhyoscyamine
• 6-Hydroxyhyoscyamine
• Anisodamine
• Benzeneacetic acid, α-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [1R-[1α,3β(S*),5α,6α]]-
• Bicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• Bicyclo[3.2.1]oct-3-yl tropate
• Hyoscyamine, 6-hydroxy-
• (αS)-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3α-yl ester
• 6-hydroxy-hyoscyamin
• Hyoscyamine, 6-hydroxy-(6ci, 7ci)
• aceanisodaMine
• alpha-(hydroxymethyl)-benzeneaceticaci6-hydroxy-8-methyl-8-azabicyclo(3.2
• (1r-(1-alpha,3-beta(s*),5-alpha,6-alpha))-.1)oct-3-yleste
• alpha-(Hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
• (αS)-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octa-3α-yl ester
• Benzeneacetic acid, alpha-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (1R-(1-alpha,3-beta(S*),5-alpha,6-alpha))-
• (αS)-α-Hydroxymethylbenzeneacetic acid (1β,5β)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-3α-yl ester
• Atropine iMpurity E (7-hydroxyhyoscyaMine)
• Benzeneacetic acid, alpha-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (alphas)-
• [S,(-)]-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-3α-yl ester

[(1S,3S,5S,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate

CAS: 55869-99-3

Fórmula: C₁₇H₂₃NO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 305.3688

Ref: IN-DA01DNA6

Atropine EP Impurity D and E (Mixture of 6-β-Hydroxyhyoscyamine and 7-β-Hydroxyhyoscyamine)

CAS: 126371-43-5, 55869-99-3

Fórmula: C₁₇H₂₃NO₄

Cor e Forma: White To Off-White Solid

Peso molecular: 305.37

Ref: 4Z-A-151007

Anisodamine

CAS: 55869-99-3

Anisodamine

Pureza: ≥98%

Peso molecular: 305.37g/mol

Ref: 54-BUP12119

6-Hydroxyhyoscyamine (Mixture of Diastereomers)

CAS: 126371-43-5, 55869-99-3

Stability Hygroscopic
Applications Mixture of 6R-Hydroxyhyoscyamine (H942815) and 6S-Hydroxyhyoscyamine (H942820). A derivative of Hyoscyamine (H674300).

Fórmula: C₁₇H₂₃NO₄

Cor e Forma: Neat

Peso molecular: 305.37

Ref: TR-H942900

6-Hydroxyhyoscyamine

CAS: 55869-99-3

6-Hydroxyhyoscyamine is a natural molecule that can bind to DNA. It has been shown to have high affinity for the 5'-GCAT-3' sequence and high specificity for the G-quadruplex structure. 6-Hydoxyhyoscyamine also has a phase transition temperature of 146°C, which may be due to the hydrogen bonds it forms with water molecules. It has been shown that 6-hydroxyhyoscyamine inhibits tumor cell growth by binding to a specific region of the promoter region of the gene encoding for growth factor β1 (GFβ1) and preventing transcription. This agent also has an inhibitory effect on tumor angiogenesis and vascular permeability, which may be related to its ability to inhibit nitric oxide production in endothelial cells. The compound is also known as anisodamine and can be used as an injection solution for patients who have had a myocardial infarct.

Fórmula: C₁₇H₂₃NO₄

Pureza: Min. 97 Area-%

Cor e Forma: Powder

Peso molecular: 305.37 g/mol

Ref: 3D-FH44857

Anisodamine

CAS: 55869-99-3

Anisodamine is similar to scopolamine & atropine, blocks muscarinic/nicotinic receptors, aids shock-related microcirculation & organophosphate studies.

Fórmula: C₁₇H₂₃NO₄

Pureza: 98% - 98.16%

Cor e Forma: Solid

Peso molecular: 305.37

Ref: TM-T21532

Atropine EP Impurity D

CAS: 55869-99-3

Fórmula: C₁₇H₂₃NO₄

Peso molecular: 305.37

Ref: ST-EA-CP-A206004