CAS 5591-45-7

Tiotixeno

Descrição:

Tiotixeno é um medicamento antipsicótico utilizado principalmente no tratamento da esquizofrenia e outros transtornos psicóticos. Pertence à classe dos tioxantenos e funciona como um antagonista dos receptores de dopamina, direcionando-se particularmente aos receptores D2 no cérebro. Essa ação ajuda a aliviar sintomas como alucinações e delírios. Tiotixeno é caracterizado por sua estrutura química, que inclui um núcleo de tioxanteno, contribuindo para suas propriedades farmacológicas. A substância é tipicamente administrada por via oral e é conhecida por seus potenciais efeitos colaterais, que podem incluir sedação, ganho de peso e sintomas extrapiramidais. É importante monitorar os pacientes quanto a esses efeitos durante o tratamento. Além disso, Tiotixeno tem uma meia-vida relativamente longa, permitindo a dosagem uma ou duas vezes ao dia. Assim como todos os medicamentos antipsicóticos, a consideração cuidadosa do perfil de risco-benefício é essencial, e deve ser prescrito sob a orientação de um profissional de saúde qualificado.

Fórmula: C₂₃H₂₉N₃O₂S₂

InChI: InChI=1/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8+

Chave InChI: InChIKey=GFBKORZTTCHDGY-UHFFFAOYSA-N

SMILES: C(CCN1CCN(C)CC1)=C2C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3

Sinónimos:

• 2-(Dimethylsulfamoyl)-[9-(4-methyl-1-piperazinyl)propylidene]thioxanthene
• Cp 12252-1
• N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide
• N,N-Dimethyl-9-[3-(4-methylpiperazin-1-yl)propyliden]-9H-thioxanthen-2-sulfonamid
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulphonamide
• N,N-dimethyl-9-[3-(4-methylpiperazine-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-dimetil-9-[3-(4-metilpiperazin-1-il)propiliden]-9H-tioxanteno-2-sulfonamida
• Navan
• Navane
• Navaron
• Nsc 108165
• Orbinamon
• P 4657B
• Thiothixene
• Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-
• Thixit
• Tiotixene
• cis-Thiothixene
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide
• (9E)-N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thiaxanthene-2-sulfona
• N,N-Dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thiaxanthene-2-sulfonamide
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, (Z)-
• 9h-thioxanthene-2-sulfonamide,n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propyl
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thioxanthene-2-sulfona
• TIOTIXENE/THIOTHIXENE
• THIOTHIXENE,USP
• THIOTHIXENE MEETS USP TESTING SPECIFICA
• CP-12,252-1 base
• (Z)-N,N-dimethyl-9-(3-(4-methylpiperazin-1-yl)
• Thiothixine
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thioxanthene-2-sulfonami
• Thiothixene (Navane)
• (9Z)-N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
• cp12252-1

Thiothixene

CAS: 5591-45-7

Thiothixene has a wide range of applications in life science related research.

Fórmula: C₂₃H₂₉N₃O₂S₂

Cor e Forma: Solid

Peso molecular: 443.62

Ref: TM-T38200

Thiothixene-13C-d3

CAS: 5591-45-7

Fórmula: C₂₂₁₃CH₂₆D₃N₃O₂S₂

Peso molecular: 447.63

Ref: 4Z-T-228002

(Z)-Thiothixene-d8

Produto Controlado

CAS: 5591-45-7

Fórmula: C₂₃H₂₁D₈N₃O₂S₂

Cor e Forma: Neat

Peso molecular: 451.67

Ref: TR-T375283

Thiothixene-d8

Produto Controlado

CAS: 5591-45-7

Thiothixene is a drug used to treat schizophrenia that belongs to the class of antipsychotics. It is a serotonin reuptake inhibitor and has been shown to be effective in treating chronic schizophrenia. Thiothixene also has anti-nervous system activities, which are due to its ability to inhibit the release of acetylcholine. This drug binds with high affinity to α7 nicotinic acetylcholine receptors and blocks the flow of chloride ions across the cell membrane, leading to an accumulation of negatively charged ions inside the cell. The drug also inhibits mineralization and has been shown to prevent structural heart disease in animals. Thiothixene may be harmful if taken with pyrite or salinity because it can cause oxidative damage in redox potential environments. The drug can also cause plasma mass spectrometry profiles that show changes in carboniferous content, which may be related to the development of nervous system diseases.

Fórmula: C₂₃H₂₁D₈N₃O₂S₂

Pureza: Min. 95%

Peso molecular: 451.67 g/mol

Ref: 3D-FAA59145