CAS 56-75-7

(-)-Cloranfenicol

Descrição:

(-)-Cloranfenicol, com o número CAS 56-75-7, é um antibiótico de amplo espectro originalmente derivado da bactéria Streptomyces venezuelae. É caracterizado por sua capacidade de inibir a síntese de proteínas bacterianas ao se ligar à subunidade 50S do ribossomo bacteriano, bloqueando efetivamente a formação de ligações peptídicas. Este composto é um pó cristalino branco a off-white que é solúvel em água e álcool, mas tem solubilidade limitada em solventes orgânicos. Sua fórmula molecular é C11H12Cl2N2O5, e tem um peso molecular de aproximadamente 323,13 g/mol. (-)-Cloranfenicol exibe atividade antibacteriana contra uma ampla gama de bactérias Gram-positivas e Gram-negativas, tornando-o útil no tratamento de várias infecções. No entanto, seu uso é limitado devido a potenciais efeitos colaterais, incluindo anemia aplástica e síndrome do bebê cinza em recém-nascidos. Como resultado, muitas vezes é reservado para infecções graves onde outros antibióticos são ineficazes. O manuseio e a dosagem adequados são cruciais para minimizar os efeitos adversos e garantir a eficácia terapêutica.

Fórmula: C₁₁H₁₂Cl₂N₂O₅

InChI: InChI=1/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9?/m1/s1

Chave InChI: InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(N(=O)=O)C=C1

Sinónimos:

• 2,2-Dichloro-N-(2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl)-Acetamid
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-Dichloro-N-[2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-dichloro-N-[(1R,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• 2,2-dichloro-N-[(1S,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• Ak-Chlor
• Alficetyn
• Amphenicol
• Amphicol
• Amseclor
• Anacetin
• Aquamycetin
• Austracol
• Bradyoxetin
• CAF
• CAM
• CAP
• CPh
• Catilan
• Chemicetin
• Chemicetina
• Chlomycol
• Chloramex
• Chloramphenicol
• Chloramsaar
• Chlorasol
• Chlorcetin
• Chloricol
• Chlorocaps
• Chlorocid
• Chlorocide
• Chlorocin
• Chloromycetin
• Chloronitrin
• Chloroptic
• Ciplamycetin
• Cloramfen
• Cloramfenicol
• Cloramficin
• Cloramicol
• Clorocyn
• Cloromisan
• Cylphenicol
• D-(-)-Chloramphenicol
• D-(-)-Threo-2,2-Dichloro-N-[Beta-Hydroxy-Alpha-(Hydroxy-Methyl)-P-Nitrophenethyl]Acetamide
• D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol
• D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
• D-(-)-threo-Chloramphenicol
• D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
• D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
• Detreomycin
• Embacetin
• Enicol
• Enteromycetin
• Farmicetina
• Fenicol
• Globenicol
• Gloveticol
• Halcetin
• Intramycetin
• Ismicetina
• Juvamycetin
• Kamaver
• Kemicetine
• Klorita
• Leukomyan
• Leukomycin
• Levocin
• Levomicetina
• Levomitsetin
• Levomycetin
• Levoplast
• Levosin
• Levovetin
• Loromisin
• Mastiphen
• Micloretin
• Micoclorina
• Microcetina
• Mychel
• Mychel-Vet
• Mycinol
• Myclocin
• Mycochlorin
• Novomycetin
• Ocuphenicol
• Opclor
• Ophthochlor
• Pantovernil
• Paraxin
• Quemicetina
• Ronphenil
• Septicol
• Sintomicetin
• Sintomicetina
• Soluthor
• Stanomycetin
• Synthomycetin
• Synthomycin
• Tevcocin
• Tifomycine
• Treomicetina
• Unimycetin
• Veticol
• Viceton
• [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• D,L-chloramphenicol
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
• nitrophenyl)ethyl]acetamide
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENETHYL]ACETAMIDE
• D-THREO-(-)-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-HYDROXYMETHYL-P-NITROPHENETHYL]ACETAMIDE
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENYL] ACETAMIDE
• D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
• D-2-DICHLOROACETAMIDO-1-P-NITRO-PHENYL-1,3-PROPANEDIOL
• [R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide
• D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE
• D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE
• D-(-)-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
• CHLORAMPHENICOLUM
• D-(-)-THREO-2-DICHLOROACETAMIDO-1-[P-NITRO-PHENYL]-1,3-PROPANEDIOL
• ,[theta-(theta,theta)]-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE

Chloramphenicol

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Peso molecular: 323.13

Ref: 4Z-C-10102

Chloramphenicol, USP grade

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: 97.0 - 103.0 %

Cor e Forma: White to light-yellow crystalline powder

Peso molecular: 323.14

Ref: 7W-GA0505

Chloramphenicol

CAS: 56-75-7

Chloramphenicol

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: >99%

Cor e Forma: solid

Peso molecular: 323.13g/mol

Ref: 54-BIC0113

Chloramphenicol (10mg/ml)

CAS: 56-75-7

Chloramphenicol (10mg/ml)

Cor e Forma: Solution

Peso molecular: 323.13g/mol

Ref: 54-BIG1028

Chloramphenicol-d5

Produto Controlado

CAS: 56-75-7

Applications Chloramphenicol-d5, is the labeled analogue of Chloramphenicol (C325030), which has a broad spectrum of activity against Gram-positive and gram-negative bacteria. It is also antibacterial, and antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Fórmula: C₁₁H₇D₅Cl₂N₂O₅

Cor e Forma: Off-White

Peso molecular: 328.16

Ref: TR-C325033

Chloramphenicol

Produto Controlado

CAS: 56-75-7

Applications Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Cor e Forma: Neat

Peso molecular: 323.13

Ref: TR-C325030

Chloramphenicol-d5 (100Mug/mL in Acetonitrile)

Produto Controlado

CAS: 56-75-7

Fórmula: C₁₁H₇D₅Cl₂N₂O₅

Cor e Forma: Colourless

Peso molecular: 328.16

Ref: TR-KIT8327

Chloramphenicol

CAS: 56-75-7

Chloramphenicol is produced by Streptomyces venezuelae. It is a broad-spectrum antibiotic with bacteriostatic properties. It interferes with bacterial protein synthesis by reversibly binding to the 50S ribosome unit. Used as substrate in the CAT (chloramphenicol acetyl transferase) assay, where the CAT gene expression is monitored by the ability of a system to transform chloramphenicol into acetyl chloramphenicol, which can be followed by simple thin layer chromatography. It is employed in VTM to prevent bacterial growth during specimen storage and transportation.

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 323.13 g/mol

Ref: 3D-AC09460

Chloramphenicol (CFP) for tissue culture, 98-102%

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: 98 - 102%

Cor e Forma: White to pale yellow, Crystalline powder, Clear

Peso molecular: 323.1

Ref: SR-28812

Chloramphenicol (CFP), 98-102%

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: min. 98-102%

Cor e Forma: White to pale yellow, Crystalline powder, Clear

Peso molecular: 323.1

Ref: SR-97686

Chloramphenicol cell culture, 99%, Endotoxin (BET) 0.2 EU/mg

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Peso molecular: 323.1

Ref: SR-17796

Chloramphenicol (CFP) ExiPlus, Multi-Compendial, 98.0-102%

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: 98.0-102%

Cor e Forma: White to pale yellow, Crystalline powder or fine crystals, Clear

Peso molecular: 323.1

Ref: SR-57956