CAS 562-10-7

Donormil

Descrição:

Donormil, conhecido cientificamente como difenidramina, é um antihistamínico utilizado principalmente por suas propriedades sedativas. É classificado como um antagonista do receptor H1 de primeira geração, o que significa que bloqueia a ação da histamina, uma substância no corpo que causa sintomas alérgicos. A difenidramina é comumente usada para aliviar os sintomas de alergias, febre do feno e resfriados comuns, bem como para induzir o sono em indivíduos que sofrem de insônia. Sua estrutura química inclui um grupo de difenilmetanol, que contribui para sua capacidade de atravessar a barreira hematoencefálica, uma característica distintiva de muitos antihistamínicos de primeira geração. Essa propriedade muitas vezes resulta em sedação, tornando-a eficaz como auxílio para dormir, mas também levando a potenciais efeitos colaterais, como sonolência, boca seca e tontura. Além disso, devido aos seus efeitos anticolinérgicos, é aconselhável ter cautela ao usá-la em pacientes idosos ou aqueles com certas condições médicas. No geral, Donormil é um medicamento versátil com benefícios terapêuticos e efeitos colaterais notáveis que requerem consideração cuidadosa durante o uso.

Fórmula: C₁₇H₂₂N₂O·C₄H₆O₄

InChI: InChI=1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16;5-3(6)1-2-4(7)8/h4-12H,13-14H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

Chave InChI: InChIKey=KBAUFVUYFNWQFM-UHFFFAOYSA-N

SMILES: C(OCCN(C)C)(C)(C1=CC=CC=C1)C2=CC=CC=N2.C(CC(O)=O)C(O)=O

Sinónimos:

• 2-[α-(2-Dimethylaminoethoxy)-α-methylbenzyl]pyridine succinate
• 2-[α-(2-Dimethylaminoethoxy)-α-methylbenzyl]pyridine succinate (1:1)
• Alsodorm
• Butanedioic acid, compd. with N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)
• Decamium
• Decapryn
• Decapryn succinate
• Decapryn succinate (1:1)
• Donormil
• Donormyl
• Dormidina
• Doxised
• Doxylamine Hydrogen Succinate
• Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-, butanedioate (1:1)
• Gittalun
• Hoggar N
• Meraprina
• Mereprine
• N,N-dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine
• N,N-dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine butanedioate (1:1)
• NSC 74772
• Pyridine, 2-[α-[2-(dimethylamino)ethoxy]-α-methylbenzyl]-, succinate (1:1)
• Sedaplus
• Succinic acid, compd. with 2-[α-[2-(dimethylamino)ethoxy]-α-methylbenzyl]pyridine (1:1)

Doxylamine Hydrogen Succinate 1.0 mg/ml in Methanol (as free base)

CAS: 562-10-7

Cor e Forma: Single Solution

Ref: 61-AMP0101.00-01

Doxylamine.succinate

CAS: 562-10-7

Cor e Forma: Neat

Ref: LP-DXL-1220-SU-10

Doxylamine Hydrogen Succinate

CAS: 562-10-7

Cor e Forma: Neat

Ref: 61-FOR0101.00

Doxylamine.succinate, 1mg/ml in Methanol (as free base)

CAS: 562-10-7

Cor e Forma: Single Solution

Ref: LP-DXL-1220-SU-1LM

DOXYLAMINE FOR SYSTEM SUITABILITY CRS

CAS: 562-10-7

DOXYLAMINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₁₇H₂₂N₂O

Peso molecular: 270.3694

Ref: 41-Y0001492

DOXYLAMINE HYDROGEN SUCCINATE CRS

CAS: 562-10-7

DOXYLAMINE HYDROGEN SUCCINATE CRS

Fórmula: C₁₇H₂₂N₂O

Peso molecular: 270.3694

Ref: 41-Y0001562

Doxylamine Succinate

CAS: 562-10-7

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₁₇H₂₂N₂O·C₄H₆O₄

Cor e Forma: White Cream Powder

Peso molecular: 388.19982

Ref: 45-1227006

Butanedioic acid, compd. withN,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)OTHER CA INDEX NAMES:Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-,butanedioate (1:1)

CAS: 562-10-7

Fórmula: C₂₁H₂₈N₂O₅

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 388.4574

Ref: IN-DA00IA19

Doxylamine succinate

CAS: 562-10-7

Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties.

Fórmula: C₂₁H₂₈N₂O₅

Pureza: 99.61%

Cor e Forma: 5 1 (Ntp 1992)

Peso molecular: 388.46

Ref: TM-T1115

Doxylamine succinate salt

CAS: 562-10-7

Fórmula: C₁₇H₂₂N₂O·C₄H₆O₄

Pureza: ≤ 1.0%

Cor e Forma: White to off-white powder

Peso molecular: 388.46

Ref: 7W-GP1654

Doxylamine succinate

CAS: 562-10-7

Doxylamine succinate

Pureza: ≥98%

Peso molecular: 388.46g/mol

Ref: 54-BUP15788

Doxylamine Succinate

CAS: 562-10-7

Fórmula: C₁₇H₂₂N₂O·C₄H₆O₄

Peso molecular: 270.38 118.09

Ref: 4Z-D-388

Doxylamine Succinate

CAS: 469-21-6, 562-10-7

Fórmula: C₁₇H₂₂N₂O·C₄H₆O₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 388.46

Ref: 3B-D5583

Doxylamine Hydrogen Succinate

CAS: 562-10-7

Cor e Forma: Off-White

Ref: 86-MM0101.00

Doxylamine Succinate

Produto Controlado

CAS: 562-10-7

Fórmula: C₁₇H₂₂N₂O·C₄H₆O₄

Cor e Forma: Off-White

Peso molecular: 388.46

Ref: TR-D562000

Doxylamine succinate

Produto Controlado

CAS: 562-10-7

Doxylamine succinate is a pharmaceutically active ingredient that is used as an antihistamine and sedative. It is a white, odorless powder with a bitter taste. Doxylamine succinate has been shown to have high resistance to degradation by gastric acid, which is why it can be administered orally or intranasally. The in vitro method of measuring the release of drug from the dosage form has been used to measure the pharmacological treatment time. In this study, doxylamine succinate was found to have a fast onset of action and short duration of action. Excipients such as metoprolol succinate and sucrose are also added to the dosage form. Toxicological studies on animals have shown liver lesions at high doses, so this drug should be taken at low doses for shorter periods of time when possible. A concentration-time curve was generated using statistical methods to control for biological variability between mice.

Fórmula: C₁₇H₂₂N₂O•C₄H₆O₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 388.46 g/mol

Ref: 3D-FD59815