CAS 56287-74-2

Afloqualona

Descrição:

Afloqualona é um composto sintético classificado como um derivado de quinazolinona, conhecido principalmente por suas propriedades relaxantes musculares e ansiolíticas. É caracterizado por sua capacidade de atuar como um depressor do sistema nervoso central, o que o torna eficaz no tratamento de condições como espasmos musculares e ansiedade. A estrutura química de Afloqualona inclui um anel de quinazolina, que contribui para sua atividade farmacológica. Geralmente é administrado por via oral e tem sido estudado por seus potenciais efeitos terapêuticos, embora seu uso possa ser limitado devido a efeitos colaterais e ao status regulatório em vários países. O composto possui uma lipofilicidade moderada, influenciando sua absorção e distribuição em sistemas biológicos. Além disso, o mecanismo de ação de Afloqualona envolve a modulação de sistemas de neurotransmissores, particularmente as vias GABAérgicas, que são cruciais para seus efeitos sedativos e relaxantes musculares. Assim como muitos fármacos, a consideração cuidadosa da dosagem e das potenciais interações com outros medicamentos é essencial para um uso seguro.

Fórmula:C₁₆H₁₄FN₃O

InChI:InChI=1/C16H14FN3O/c1-10-4-2-3-5-14(10)20-15(9-17)19-13-7-6-11(18)8-12(13)16(20)21/h2-8H,9,18H2,1H3

Chave InChI:InChIKey=VDOSWXIDETXFET-UHFFFAOYSA-N

SMILES:C(F)C=1N(C(=O)C=2C(N1)=CC=C(N)C2)C3=C(C)C=CC=C3

Sinónimos:

(2-Tolyl)-3H-quinazolin-4-one
4(3H)-quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one
6-Amino-2-Fluoromethyl-3-
Aroft
Arofuto
H 495
Hq 495
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
Afloqualone
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-fluoromethyl-3-(o-tolyl)-quinazolin-4(3H)-one
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3h)-quinazolinon
6-Amino-2-Fluoromethyl-3-(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
6-amino-2-fluoromethyl-3-(o-tolyl)-4(3h)-quinazolinon
Ver mais sinónimos

Pureza (%)

100

4 produtos.

+ Info
4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
CAS:
- 56287-74-2
Fórmula:C₁₆H₁₄FN₃O
Pureza:98%
Cor e Forma:Solid
Peso molecular:283.3003
Ref: IN-DA00IA22
100mg
140,00€
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250mg
202,00€
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500mg
322,00€
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Afloqualone
CAS:
- 56287-74-2
Afloqualone (HQ-495) is a GABA Receptor agonist with sedative and muscle-relaxant properties.
Fórmula:C₁₆H₁₄FN₃O
Pureza:99.72%
Cor e Forma:Solid
Peso molecular:283.3
Ref: TM-T4993
+ Info
Afloqualone
CAS:
- 56287-74-2
Applications Afloqualone acts as a muscle relaxant in humans and may be used in the treatment of muscle spasms affecting rheumatoid arthritis. References Farkas, S. et al.: J. Pharm. Toxicol. Meth., 52, 264 (2005); Yun, H. et al.: Talanta, 73, 635 (2007); 
Fórmula:C₁₆H₁₄FN₃O
Cor e Forma:White To Off-White
Peso molecular:283.30
Ref: TR-A357700
250mg
171,00€
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6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
Produto ControladoTenha em atenção que se trata de um produto controlado em alguns países e que tem de ser tratado em conformidade com os regulamentos relevantes. Esteja ciente de que isto pode implicar despesas e documentação adicionais.
CAS:
- 56287-74-2
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is a potent inhibitor of the enzyme dihydrofolate reductase, which is required for the synthesis of DNA and other macromolecules. It has been shown to inhibit the growth of cutaneous lesions in mice and rats. The compound has also been found to be effective against renal lesions (caused by cevimeline hydrochloride) in rats. The compound has a high inhibitory dose as it binds tightly with divalent metal ions such as magnesium, calcium, and zinc. This property may result in its use as an anticancer drug. 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is soluble in water and polymeric matrices and can be administered orally or intravenously.
Fórmula:C₁₆H₁₄FN₃O
Pureza:Min. 95%
Cor e Forma:White Powder
Peso molecular:283.3 g/mol
Ref: 3D-FA29178
1g
713,00€
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50mg
135,00€
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100mg
183,00€
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250mg
382,00€
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500mg
509,00€
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