CAS 56796-39-5
:Cefmetazol sódico
Descrição:
Cefmetazol sódico é um antibiótico cefalosporínico semissintético, classificado sob o grupo de antibióticos beta-lactâmicos. É utilizado principalmente por sua atividade antibacteriana de amplo espectro contra várias bactérias Gram-positivas e Gram-negativas. O cefmetazol atua inibindo a síntese da parede celular bacteriana, levando à lise e morte celular. O composto é tipicamente administrado por injeção e é eficaz no tratamento de infecções como infecções do trato respiratório, infecções de pele e infecções do trato urinário. É caracterizado por sua estabilidade contra certas beta-lactamases, o que aumenta sua eficácia contra cepas bacterianas resistentes. Cefmetazol sódico é geralmente bem tolerado, embora os efeitos colaterais potenciais possam incluir reações alérgicas, distúrbios gastrointestinais e alterações na coagulação sanguínea. Sua farmacocinética envolve rápida absorção e distribuição nos tecidos do corpo, com a excreção renal sendo a principal via de eliminação. Assim como todos os antibióticos, testes de suscetibilidade apropriados são recomendados para garantir sua eficácia contra patógenos específicos.
Fórmula:C15H17N7O5S3
InChI:InChI=1/C15H17N7O5S3.Na/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25;/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25);/q;+1/p-1/t13?,15-;/m0./s1
Chave InChI:InChIKey=QTNLVCQCRNPXAJ-PBCQUBLHSA-N
SMILES:N(C(CSCC#N)=O)[C@@]1(OC)[C@@]2(N(C1=O)C(C(O)=O)=C(CSC=3N(C)N=NN3)CS2)[H].[Na]
Sinónimos:- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, monosodium salt, (6R-cis)-
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, sodium salt, (6R-cis)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt (1:1), (6R,7S)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-
- CMZ sodium
- CS 1170 sodium
- CS-1170 sodium salt
- Cefmetazole sodium [USAN:JAN]
- Cefmetazole-Na
- Cefmetazon
- Cefmetazone
- Metafar
- Metazol
- SKF 83088 sodium
- Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate
- Sodium cefmetazole
- U 72791A
- Unii-37Y9Vr4W7A
- Zefazone
- Zefazone in plastic container
- sodium (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- sodium (7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- (6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
- (6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
- CEFMETAZOLE
- Cefmetazole sodium
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100
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11 produtos.
Cefmetazole sodium, 921μg/mg
CAS:<p>Cefmetazole is used to study the effect of expression, binding, and inhibition of penicillin-binding proteins (with the exception of PBP2) on bacterial cell wall mucopeptide synthesis. It is also used to study protein mediated antibiotic transport. This Thermo Scientific Chemicals brand product was </p>Fórmula:C15H16N7O5S3NaPeso molecular:493.52Cefmetazole sodium
CAS:Cefmetazole sodium: semisynthetic cephamycin, broad-spectrum, effective against infections, no severe side effects.Fórmula:C15H16N7NaO5S3Pureza:92.05% - 99.87%Cor e Forma:White SolidPeso molecular:493.52Cefotetan Impurity 1 Sodium Salt (Cefmetazole Sodium Salt)
CAS:Fórmula:C15H16N7O5S3·NaCor e Forma:White To Off-White SolidPeso molecular:470.53 22.99Cefmetazole sodium salt
CAS:Fórmula:C15H16N7O5S3NaCor e Forma:White to off-white or pale yellow powderPeso molecular:493.52Cefmetazole Sodium Salt
CAS:Fórmula:C15H16N7NaO5S3Pureza:>92.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:493.51Cefmetazole Sodium
CAS:Produto Controlado<p>Applications Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.<br>References Zhou, G., et al.: Zhonghua Zhongyiyao Xuekan, 32, 622 (2014); Luo, Y., et al.: Zhongguo Yiyuan Yaoxue Zazhi, 34, 1851 (2014); Fan, M., et al.: Shiyong Yaowu Yu Linchuang, 15, 10 (2012)<br></p>Fórmula:C15H16N7O5S3·NaCor e Forma:NeatPeso molecular:493.52Cefmetazole sodium
CAS:<p>Cefmetazole sodium is a penicillin-type antibiotic that inhibits the synthesis of bacterial cell walls. It binds to the penicillin-binding proteins in the bacterial cell wall by competitive inhibition, preventing the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Cefmetazole sodium has been shown to be active against a wide variety of bacteria, including gram-positive and gram-negative bacteria. The drug's activity against most strains of methicillin-resistant Staphylococcus aureus (MRSA) has been confirmed. Cefmetazole sodium is used to treat infectious diseases such as pneumonia and urinary tract infections. Drug interactions are possible, but not well understood at this time.</p>Fórmula:C15H17N7O5S3•NaPureza:Min. 93 Area-%Cor e Forma:PowderPeso molecular:494.53 g/mol
