CAS 58-14-0

2,4-Pirimidinediamina, 5-(4-clorofenil)-6-etil-

Descrição:

2,4-Pirimidinediamina, 5-(4-clorofenil)-6-etil-, comumente conhecido como Etilo 5-(4-clorofenil)-2,4-pirimidinediamina, é um composto orgânico caracterizado por sua estrutura de anel de pirimidina, que é um heterociclo aromático de seis membros contendo dois átomos de nitrogênio nas posições 2 e 4. Este composto apresenta um grupo etila na posição 6 e um grupo para-clorofenila na posição 5, contribuindo para suas propriedades químicas únicas. Normalmente é um sólido à temperatura ambiente e pode exibir solubilidade moderada em solventes polares. A presença de grupos amino na estrutura permite uma reatividade potencial, incluindo ligações de hidrogênio e substituição nucleofílica. Este composto é de interesse em vários campos, incluindo farmacêuticos e agroquímicos, devido à sua potencial atividade biológica. Os dados de segurança indicam que deve ser manuseado com cuidado, pois pode representar riscos à saúde quando exposto. Protocolos adequados de armazenamento e manuseio são essenciais para garantir segurança e estabilidade.

Fórmula: C₁₂H₁₃ClN₄

InChI: InChI=1/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

Chave InChI: InChIKey=WKSAUQYGYAYLPV-UHFFFAOYSA-N

SMILES: C(C)C=1C(=C(N)N=C(N)N1)C2=CC=C(Cl)C=C2

Sinónimos:

• 2, 4-Diamino-5-(4'-chlorophenyl)-6-ethylpyrimidine
• 2, 4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
• 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
• 2,4-Diamino-5-p-chlorophenyl-6-ethylpyrimidine
• 4753 R.P.
• 5-(4-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
• 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
• 5-(P-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
• Bw 50-63
• Chloridin
• Chloridine
• Darachlor
• Darapram
• Daraprim
• Daraprime
• Diaminopyritamin
• Erbaprelina
• Khloridin
• Malacid
• Malocid
• Malocide
• Nsc 3061
• Pirimecidan
• Pirimetamin
• Pirimetamina
• Pyrimethamin
• Pyrimethamine
• Pyrimethamine Base
• Pyrimidine, 2,4-diamino-5-(p-chlorophenyl)-6-ethyl-
• Rp 4753
• Tindurin
• Tinduring
• Wr 2978
• 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
• 2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-
• 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diyldiamine
• 5-(p-chlorophenyl)-6-ethyl-4-pyrimidinediamine
• 2,4-Pyrimidinediamine, 5-(p-chlorophenyl)-6-ethyl-
• 4753r.p.
• 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
• bw50-63

Pyrimethamine

CAS: 58-14-0

Fórmula: C₁₂H₁₃ClN₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 248.71

Ref: 3B-P2037

Pyrimethamine

CAS: 58-14-0

Cor e Forma: Neat

Ref: 61-FOR1630.00

PYRIMETHAMINE CRS

CAS: 58-14-0

PYRIMETHAMINE CRS

Fórmula: C₁₂H₁₃ClN₄

Cor e Forma: Crystalline Powder. White. Colourless Crystals. Powder.

Peso molecular: 248.7114

Ref: 41-P4200000

PYRIMETHAMINE RS

CAS: 58-14-0

PYRIMETHAMINE RS

Fórmula: C₁₂H₁₃ClN₄

Peso molecular: 248.7114

Ref: 41-ICRS47051

Pyrimethamine

CAS: 58-14-0

Pyrimethamine

Fórmula: C₁₂H₁₃CIN₄

Pureza: 99.5%

Cor e Forma: White

Peso molecular: 352.01849

Ref: 47-1227

Pyrimethamine

CAS: 58-14-0

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₁₂H₁₃ClN₄

Cor e Forma: White Powder

Peso molecular: 248.08287

Ref: 45-1589007

2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-

CAS: 58-14-0

Fórmula: C₁₂H₁₃ClN₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 248.7114

Ref: IN-DA00IKHO

Pyrimethamine

CAS: 58-14-0

Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.

Fórmula: C₁₂H₁₃ClN₄

Pureza: 99.67%

Cor e Forma: Crystals

Peso molecular: 248.71

Ref: TM-T0849

Pyrimethamine

CAS: 58-14-0

Pyrimethamine

Pureza: ≥98%

Peso molecular: 248.71g/mol

Ref: 54-BUP14770

Pyrimethamine

CAS: 58-14-0

Pyrimethamine

Pureza: 98%

Peso molecular: 248.71g/mol

Ref: 54-OR1029094

Pyrimethamine-d3-15N3

CAS: 58-14-0

Fórmula: N₃C₁₂H₁₀D₃ClN

Cor e Forma: Off-White Solid

Peso molecular: 254.71

Ref: 4Z-P-154004

Pyrimethamine

Produto Controlado

CAS: 58-14-0

Fórmula: C₁₂H₁₃ClN₄

Cor e Forma: White To Off-White

Peso molecular: 248.71

Ref: 86-MM1630.00

Pyrimethamine

Produto Controlado

CAS: 58-14-0

Fórmula: C₁₂H₁₃ClN₄

Cor e Forma: Neat

Peso molecular: 248.71

Ref: 04-C16658000

Pyrimethamine

CAS: 58-14-0

Fórmula: C₁₂H₁₃ClN₄

Peso molecular: 248.72

Ref: 4Z-P-154001

Pyrimethamine-d5

CAS: 58-14-0

Fórmula: C₁₂H₈D₅ClN₄

Peso molecular: 253.74

Ref: 4Z-P-154003

Pyrimethamine

Produto Controlado

CAS: 58-14-0

Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.
References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),

Fórmula: C₁₂H₁₃ClN₄

Cor e Forma: White To Off-White

Peso molecular: 248.71

Ref: TR-P997240

Pyrimethamine

CAS: 58-14-0

Pyrimethamine is an antimalarial agent that has been used in the treatment of various infectious diseases. Pyrimethamine is a folic acid antagonist which inhibits the synthesis of DNA and RNA by inhibiting the enzyme dihydrofolate reductase. The drug binds to sulfadiazine, a sulfa drug, which prevents its conversion to active form and thereby prevents bacterial growth. Pyrimethamine can be administered orally or intravenously. It exhibits low toxicity and is excreted in the urine as an inactive metabolite. In vitro assays have shown pyrimethamine to be effective against HIV-1 infection, but it is not active against other viruses such as herpes simplex virus and influenza virus.

Fórmula: C₁₂H₁₃ClN₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 248.71 g/mol

Ref: 3D-FP27346

5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4-diamine

CAS: 58-14-0

Fórmula: C₁₂H₁₃ClN₄

Pureza: 95%

Cor e Forma: No data available.

Peso molecular: 248.71

Ref: 10-F211965