CAS 58-28-6
:Cloridrato de desipramina
Descrição:
Cloridrato de desipramina é um antidepressivo tricíclico usado principalmente no tratamento do transtorno depressivo maior e certos transtornos de ansiedade. Funciona inibindo a recaptação de norepinefrina e, em menor grau, de serotonina, aumentando assim os níveis desses neurotransmissores na fenda sináptica. Esse mecanismo contribui para seus efeitos antidepressivos. A substância aparece como um pó cristalino branco a off-white e é solúvel em água, tornando-a adequada para administração oral em forma de comprimidos ou como solução injetável. Cloridrato de desipramina tem uma meia-vida relativamente longa, permitindo a dosagem uma vez ao dia em muitos casos. Os efeitos colaterais comuns podem incluir boca seca, constipação, retenção urinária e sedação, enquanto os riscos mais sérios envolvem problemas cardiovasculares e potencial de overdose. Devido ao seu perfil de efeitos colaterais, geralmente é prescrito com cautela, particularmente em pacientes com condições cardíacas preexistentes. Como com todos os medicamentos, é essencial que os pacientes consultem profissionais de saúde para obter aconselhamento personalizado e monitoramento durante o tratamento.
Fórmula:C18H23ClN2
InChI:InChI=1/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H
Chave InChI:InChIKey=XAEWZDYWZHIUCT-UHFFFAOYSA-N
SMILES:C(CCNC)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Sinónimos:- 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine hydrochloride
- 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride
- 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride (1:1)
- 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine hydrochloride
- 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride
- 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, monohydrochloride
- 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-, hydrochloride (1:1)
- DMI hydrochloride
- Demethylimipramine hydrochloride
- Desimipramine, hydrochloride
- Desipramine HCl
- Desipramine hydrochloride [USAN:JAN]
- Desipramine monohydrochloride
- Desmethylimipramine chloride
- Desmethylimipramine hydrochloride
- Desmethylimipramine monohydrochloride
- Despramine Hydrochloride
- Ex 4355
- G 35020
- GMI
- Imipraminedemethyl hydrochloride
- Jb 8181
- N-(gamma-Methylaminopropyl)iminodibenzyl hydrochloride
- N-(γ-Methylaminopropyl)iminodibenzyl hydrochloride
- Norpolake
- Norpramin
- Nortimil
- Nortrimil
- Nsc 114901
- Pertofran
- Pertofrane
- Pertofrin
- Petilil
- Petylyl
- Rmi 9,384A
- Unii-1Y58Do4My1
- Desipramine hydrochloride
- n-(gamma-methylaminopropyl)iminodibenzylhydrochloride
- demethylimipraminehydrochloride
- Desipramine solution hydrochloride
- f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(monohydrochlor
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine
- Desipramine Hydrochloride (125 mg)I0E2831.000mg/mg(dr)
- Desipramine hydrochloride solution
- desmethylimipraminehydrochloride
- dmihydrochloride
- 5H-Dibenzb,fazepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
- imipraminedemethylhydrochloride
- g35020
- ex4355
- 10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(b,f)azepinehydrochloride
- 3-(5,6-dihydrobenzo[b][1
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methyl-amine
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine hydrochloride
- 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine hydrochloride
- jb8181
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
- Desipramine Hydrochloride (125 mg)
- [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine hydrochloride
- 10,11-DIHYDRO-N-METHYL-5-H-DIBENZ-[B,F]AZEPINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(hydrochlorid
- DESIPRAMINEHYDROCHLORIDE,USP
- DESIPRAMINE HYDROCHLORIDE METHANOL*SOLUT ION
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17 produtos.
Desipramine hydrochloride
CAS:Desipramine hydrochlorideFórmula:C18H23ClN2Cor e Forma:Off-WhitePeso molecular:302.8416DESIPRAMINE HYDROCHLORIDE CRS
CAS:DESIPRAMINE HYDROCHLORIDE CRSFórmula:C18H23ClN2Cor e Forma:Crystalline Powder. White. Powder.Peso molecular:302.8416Desipramine Hydrochloride
CAS:Antidepressants, tranquilizers and other psychotherapeutic agents, nesoiFórmula:C18H22N2·HClCor e Forma:White Off-White PowderPeso molecular:302.15498Desipramine hydrochloride
CAS:Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.Fórmula:C18H23ClN2Pureza:99.58% - 99.96%Cor e Forma:White To Off-White PowderPeso molecular:302.84Desipramine hydrochloride
CAS:Fórmula:C18H22N2·HClPureza:≥ 97.0%Cor e Forma:White to off-white powderPeso molecular:302.84Desipramine Hydrochloride
CAS:Produto ControladoFórmula:C18H22N2·ClHCor e Forma:NeatPeso molecular:302.84Desipramine Hydrochloride
CAS:Fórmula:C18H22N2·HClPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:302.85Desipramine Hydrochloride
CAS:Produto ControladoApplications Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),Fórmula:C18H22N2·ClHCor e Forma:Off-WhitePeso molecular:302.84Desipramine HCl
CAS:Produto ControladoDesipramine hydrochloride is a tricyclic antidepressant drug that has been used to treat depression. It is an ester of N-methyl-D-aspartate and inhibits the 5-HT2 receptors. Desipramine HCl has been shown to have anti-cancer properties in both animal models and human cell lines, inhibiting carcinoma cells’ growth. The drug also has an effect on locomotor activity in mice and its use may cause drug interactions with nonsteroidal anti-inflammatory drugs.
Fórmula:C18H23ClN2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:302.84 g/mol
