CAS 58-28-6

Cloridrato de desipramina

Descrição:

Cloridrato de desipramina é um antidepressivo tricíclico usado principalmente no tratamento do transtorno depressivo maior e certos transtornos de ansiedade. Funciona inibindo a recaptação de norepinefrina e, em menor grau, de serotonina, aumentando assim os níveis desses neurotransmissores na fenda sináptica. Esse mecanismo contribui para seus efeitos antidepressivos. A substância aparece como um pó cristalino branco a off-white e é solúvel em água, tornando-a adequada para administração oral em forma de comprimidos ou como solução injetável. Cloridrato de desipramina tem uma meia-vida relativamente longa, permitindo a dosagem uma vez ao dia em muitos casos. Os efeitos colaterais comuns podem incluir boca seca, constipação, retenção urinária e sedação, enquanto os riscos mais sérios envolvem problemas cardiovasculares e potencial de overdose. Devido ao seu perfil de efeitos colaterais, geralmente é prescrito com cautela, particularmente em pacientes com condições cardíacas preexistentes. Como com todos os medicamentos, é essencial que os pacientes consultem profissionais de saúde para obter aconselhamento personalizado e monitoramento durante o tratamento.

Fórmula: C₁₈H₂₃ClN₂

InChI: InChI=1/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H

Chave InChI: InChIKey=XAEWZDYWZHIUCT-UHFFFAOYSA-N

SMILES: C(CCNC)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Sinónimos:

• 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine hydrochloride
• 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride
• 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride (1:1)
• 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine hydrochloride
• 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride
• 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, monohydrochloride
• 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-, hydrochloride (1:1)
• DMI hydrochloride
• Demethylimipramine hydrochloride
• Desimipramine, hydrochloride
• Desipramine HCl
• Desipramine hydrochloride [USAN:JAN]
• Desipramine monohydrochloride
• Desmethylimipramine chloride
• Desmethylimipramine hydrochloride
• Desmethylimipramine monohydrochloride
• Despramine Hydrochloride
• Ex 4355
• G 35020
• GMI
• Imipraminedemethyl hydrochloride
• Jb 8181
• N-(gamma-Methylaminopropyl)iminodibenzyl hydrochloride
• N-(γ-Methylaminopropyl)iminodibenzyl hydrochloride
• Norpolake
• Norpramin
• Nortimil
• Nortrimil
• Nsc 114901
• Pertofran
• Pertofrane
• Pertofrin
• Petilil
• Petylyl
• Rmi 9,384A
• Unii-1Y58Do4My1
• Desipramine hydrochloride
• n-(gamma-methylaminopropyl)iminodibenzylhydrochloride
• demethylimipraminehydrochloride
• Desipramine solution hydrochloride
• f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(monohydrochlor
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine
• Desipramine Hydrochloride (125 mg)I0E2831.000mg/mg(dr)
• Desipramine hydrochloride solution
• desmethylimipraminehydrochloride
• dmihydrochloride
• 5H-Dibenzb,fazepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
• imipraminedemethylhydrochloride
• g35020
• ex4355
• 10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(b,f)azepinehydrochloride
• 3-(5,6-dihydrobenzo[b][1
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methyl-amine
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine hydrochloride
• 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine hydrochloride
• jb8181
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
• Desipramine Hydrochloride (125 mg)
• [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine hydrochloride
• 10,11-DIHYDRO-N-METHYL-5-H-DIBENZ-[B,F]AZEPINE HYDROCHLORIDE
• f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(hydrochlorid
• DESIPRAMINEHYDROCHLORIDE,USP
• DESIPRAMINE HYDROCHLORIDE METHANOL*SOLUT ION

Desipramine.HCl

CAS: 58-28-6

Cor e Forma: Neat

Ref: LP-DSP-1093-HC-10

Desipramine.HCl, 1mg/ml in Methanol (as free base)

CAS: 58-28-6

Cor e Forma: Single Solution

Ref: LP-DSP-1093-HC-1LM

Desipramine Hydrochloride

CAS: 58-28-6

Cor e Forma: Neat

Ref: 61-FOR0589.00

Desipramine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 58-28-6

Cor e Forma: Single Solution

Ref: 61-AMP0589.00-01

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride

Fórmula: C₁₈H₂₃ClN₂

Cor e Forma: Off-White

Peso molecular: 302.8416

Ref: 47-931

DESIPRAMINE HYDROCHLORIDE CRS

CAS: 58-28-6

DESIPRAMINE HYDROCHLORIDE CRS

Fórmula: C₁₈H₂₃ClN₂

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 302.8416

Ref: 41-D0500000

Desipramine Hydrochloride

CAS: 58-28-6

Antidepressants, tranquilizers and other psychotherapeutic agents, nesoi

Fórmula: C₁₈H₂₂N₂·HCl

Cor e Forma: White Off-White Powder

Peso molecular: 302.15498

Ref: 45-1172006

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.

Fórmula: C₁₈H₂₃ClN₂

Pureza: 99.58% - 99.94%

Cor e Forma: White To Off-White Powder

Peso molecular: 302.842

Ref: TM-T0991

Desipramine HCl

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·HCl

Peso molecular: 266.39 36.46

Ref: 4Z-D-026

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride

Pureza: ≥98%

Peso molecular: 302.842g/mol

Ref: 54-BUP14958

Desipramine Hydrochloride

CAS: 58-28-6

Desipramine Hydrochloride

Pureza: 98%

Peso molecular: 302.84g/mol

Ref: 54-OR1027543

Desipramine hydrochloride

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·HCl

Pureza: ≥ 97.0%

Cor e Forma: White to off-white powder

Peso molecular: 302.84

Ref: 7W-GP4485

Desipramine Hydrochloride

Produto Controlado

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·ClH

Cor e Forma: Neat

Peso molecular: 302.84

Ref: 86-MM0589.00

Desipramine hydrochloride

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·ClH

Cor e Forma: Neat

Peso molecular: 302.84

Ref: 04-C12170167

Desipramine Hydrochloride

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·HCl

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 302.85

Ref: 3B-D6181

Desipramine Hydrochloride

Produto Controlado

CAS: 58-28-6

Applications Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),

Fórmula: C₁₈H₂₂N₂·ClH

Cor e Forma: Off-White

Peso molecular: 302.84

Ref: TR-D290050

Desipramine HCl

Produto Controlado

CAS: 58-28-6

Desipramine hydrochloride is a tricyclic antidepressant drug that has been used to treat depression. It is an ester of N-methyl-D-aspartate and inhibits the 5-HT2 receptors. Desipramine HCl has been shown to have anti-cancer properties in both animal models and human cell lines, inhibiting carcinoma cells’ growth. The drug also has an effect on locomotor activity in mice and its use may cause drug interactions with nonsteroidal anti-inflammatory drugs.

Fórmula: C₁₈H₂₃ClN₂

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 302.84 g/mol

Ref: 3D-FD21203