CAS 58-55-9

Teofilina

Descrição:

Teofilina é um composto de metilxantina que ocorre naturalmente, encontrado principalmente nas folhas de chá e no cacau. É classificado como um broncodilatador, o que significa que ajuda a relaxar e abrir as vias aéreas nos pulmões, sendo útil no tratamento de doenças respiratórias como asma e doença pulmonar obstrutiva crônica (DPOC). A fórmula química de Teofilina é C7H8N4O2, e tem um peso molecular de aproximadamente 180,17 g/mol. Teofilina apresenta uma solubilidade moderada em água e é mais solúvel em solventes orgânicos. Sua estrutura apresenta um sistema de anel semelhante à purina, o que contribui para sua atividade biológica. Teofilina atua inibindo as enzimas fosfodiesterase, levando a níveis aumentados de AMP cíclico, o que promove o relaxamento do músculo liso brônquico. Além disso, possui propriedades anti-inflamatórias e pode melhorar a função muscular respiratória. Embora geralmente seja bem tolerado, Teofilina pode ter efeitos colaterais, particularmente em doses mais altas, incluindo distúrbios gastrointestinais, insônia e aumento da frequência cardíaca. Seu uso terapêutico requer monitoramento cuidadoso dos níveis sanguíneos devido ao seu estreito índice terapêutico.

Fórmula: C₇H₈N₄O₂

InChI: InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)

Chave InChI: InChIKey=ZFXYFBGIUFBOJW-UHFFFAOYSA-N

SMILES: O=C1C2=C(N(C)C(=O)N1C)N=CN2

Sinónimos:

• 1,3-Dimethyl-1H-purine-2,6(3H,7H)-dione
• 1,3-Dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• 1,3-Dimethyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione
• 1,3-Dimethyl-3,7-dihydro-purine-2,6-dione
• 1,3-Dimethylxanthine
• 1,3-dimethyl-3,4,5,7-tetrahydro-1H-purine-2,6-dione
• 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
• 3,9-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
• Accurbron
• Aerobin
• Aerolate
• Afonilm
• Apnecut
• Armophylline
• Asmax
• Austyn
• Bilordyl
• Brochoretard
• Bronkodyl
• Cetraphylline
• Chronophyllin
• Diffumal
• Dimethylxanthine
• Duraphyl
• Duraphyllin
• Egifilin
• Elan
• Elixophyllin
• Elixophylline
• Etheophyl
• Euphylong
• Insanovin
• LaBID
• Lanophyllin
• Lasma
• Liquophylline
• Nuelin
• Optiphyllin
• Parkophyllin
• Phylobid
• Physpan
• Pro-Vent
• Pseudotheophylline
• PulmiDur
• Pulmo-Timelets
• Respbid
• Respicur
• Slo-Bid
• Slo-Phyllin
• Solosin
• Sustaire
• Talotren
• Telb-DS
• Telbans
• Teofilina
• Teonova
• Teotard
• Tesona
• Theo-DS
• Theo-Dur
• Theo-Nite
• Theo-Sav
• Theobid
• Theochron
• Theoclear
• Theodel
• Theodrip
• Theofol
• Theograd
• Theolair
• Theon
• Theopek
• Theophyl
• Theophyllin
• Theoplus
• Theostat
• Theotard
• Theovent
• Throphylline
• Unifyl
• Unilong
• Uniphyl
• Uniphyllin
• Xanthium
• 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-
• 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-

Aminophylline

CAS: 317-34-0, 58-55-9

Fórmula: C₁₄H₁₆N₈O₄·C₂H₈N₂

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 420.43

Ref: 3B-A2805

Theophylline

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 180.17

Ref: 3B-T0179

Theophylline

CAS: 58-55-9

Theophylline has been used to study its effects on rat gene expression in the ubiquitin-proteasome pathway that regulates spermatogenesis and epididymal sperm quality. Theophylline has also been used as an internal standard for the measurement of plasma paracetamol levels in humans. This Thermo Scie

Fórmula: C₇H₈N₄O₂

Cor e Forma: White to off-white, Powder

Peso molecular: 180.17

Ref: 02-J60203

Theophylline, 1mg/ml in Methanol

Produto Controlado

CAS: 58-55-9

Cor e Forma: Single Solution

Ref: LP-TPY-133-FB-1LM

Theophylline

CAS: 58-55-9

Cor e Forma: Neat

Ref: LP-TPY-133-FB-10

Theophylline

Produto Controlado

CAS: 58-55-9

Cor e Forma: Neat

Ref: 61-FOR0176.00

THEOPHYLLINE CRS

CAS: 58-55-9

THEOPHYLLINE CRS

Ref: 41-T0800000

Theophylline

CAS: 58-55-9

Theophylline

Fórmula: C₇H₈N₄O₂

Pureza: 99.9%

Cor e Forma: White Solid

Peso molecular: 180.06473

Ref: 47-327

Theophylline

CAS: 58-55-9

Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or included

Fórmula: C₇H₈N₄O₂

Cor e Forma: White Powder

Peso molecular: 180.17 g/mol

Ref: 45-1653004

Theophylline Melting Point Standard (Approximately 271 degrees)

CAS: 58-55-9

Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or included

Fórmula: C₇H₈N₄O₂

Cor e Forma: White Crystalline Powder

Peso molecular: 180.06473

Ref: 45-1653117

Theophylline

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 180.1640

Ref: IN-DA00IABC

Theophylline

CAS: 58-55-9

Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central

Fórmula: C₇H₈N₄O₂

Pureza: 99.65% - 99.98%

Cor e Forma: White Solid Powder

Peso molecular: 180.16

Ref: TM-T1083

Theophylline (Dimenhydrinate EP Impurity A, Diprophylline EP Impurity B)

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Cor e Forma: White To Off-White Solid

Peso molecular: 180.17

Ref: 4Z-T-605

Theophylline

CAS: 58-55-9

Theophylline

Pureza: ≥98%

Peso molecular: 180.16g/mol

Ref: 54-BUP18605

Theophylline

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Pureza: ≥ 99.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 180.16

Ref: 7W-GP6302

Theophylline

Produto Controlado

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Cor e Forma: Neat

Peso molecular: 180.16

Ref: 86-MM0176.00

Theophylline

Produto Controlado

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Cor e Forma: Neat

Peso molecular: 180.16

Ref: 04-C17446000

Theophylline 100 µg/mL in Acetonitrile

Produto Controlado

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Cor e Forma: Single Solution

Peso molecular: 180.16

Ref: 04-A17446000AL-100

Theophylline

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Pureza: 95%~99%

Peso molecular: 180.167

Ref: BP-BP1390

Theophylline 1.0 mg/ml in Methanol

Produto Controlado

CAS: 58-55-9

Cor e Forma: Single Solution

Ref: 61-AMP0176.00-01

Theophylline

CAS: 58-55-9

Theophylline

Fórmula: C₇H₈N₄O₂

Pureza: ≥ 98.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 180.17

Ref: 5G-82668

Caffeine EP Impurity A

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Peso molecular: 180.16

Ref: ST-EA-CP-C47001

Theophylline

Produto Controlado

CAS: 58-55-9

Applications Xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975); Svedmyr, K., et al.: Allergy, 37, 111 (1982);

Fórmula: C₇H₈N₄O₂

Cor e Forma: Off-White

Peso molecular: 180.16

Ref: TR-T343850

Theophylline

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 180.167

Ref: 10-F095062

1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine

Produto Controlado

CAS: 58-55-9

1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine (1,3DMP) is a drug that has been used experimentally as a congestive heart failure treatment. It is an analogue of theophylline and has been shown to have similar effects on the cardiovascular system. 1,3DMP can be metabolized by cytochrome P450 enzymes to form compounds that are active in the nucleus of cells and may affect gene expression. The drug has also been shown to have a protective effect on the bowel when administered with anhydrous sodium sulphate. 1,3DMP binds to DNA in the nucleus of cells and inhibits nuclear dna synthesis by competitive inhibition with the natural substrate S-adenosylmethionine. This binding prevents transcription of DNA into RNA and protein synthesis. 1,3DMP also binds to proteins in human serum and has pharmacological activities such as

Fórmula: C₇H₈N₄O₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 180.16 g/mol

Ref: 3D-FT28196

Theophylline anhydrous pure, 99%

CAS: 58-55-9

Fórmula: C₇H₈N₄O₂

Pureza: min. 99%

Cor e Forma: White to off -white to light yellow, Crystalline powder

Peso molecular: 180.16

Ref: SR-56135