CAS 59-01-8

Canamicina A

Descrição:

Canamicina A é um antibiótico aminoglicosídeo que é usado principalmente para tratar infecções bacterianas, particularmente aquelas causadas por bactérias Gram-negativas. É derivado da bactéria *Micromonospora kanamycetica*. Canamicina A exibe um amplo espectro de atividade antibacteriana e atua inibindo a síntese de proteínas nas bactérias, levando à morte celular. O composto é caracterizado por sua estrutura complexa, que inclui múltiplos açúcares amino e um núcleo de 2-deoxiestreptamina. Geralmente é administrado por injeção ou intravenosamente devido à sua má absorção no trato gastrointestinal. Canamicina A é conhecido por seu potencial nefrotóxico e ototóxico, exigindo monitoramento cuidadoso da função renal e da audição em pacientes em tratamento. Além disso, a resistência à kanamicina pode se desenvolver, muitas vezes através da modificação enzimática pelas bactérias. Seu uso é geralmente reservado para infecções específicas, particularmente em casos onde outros antibióticos são ineficazes ou contraindicados. No geral, Canamicina A continua sendo uma ferramenta importante no arsenal de antibióticos, especialmente no tratamento de infecções multirresistentes.

Fórmula: C₁₈H₃₆N₄O₁₁

InChI: InChI=1/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1

Chave InChI: InChIKey=SBUJHOSQTJFQJX-NOAMYHISSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](N)C[C@H]1N)[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O

Sinónimos:

• (1S,2R,3R,4S,6R)-4,6-diamino-3-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
• 4))-2-Deoxy-Y-Alpha-D-Glucopyranosyl-(
• 4,6-Diamino-2-Hydroxy-1,3-Cyclohexane3,6’Diamino-3,6'-Dideoxydi-Alpha-D-Gluc
• 4,6-Diamino-2-Hydroxy-1,3-Cyclohexane3,6’Diamino-3,6’-Dideoxydi-Alpha-D-Glucos
• 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6'-diamino-3,6'-dideoxydi-α-D-glucoside
• 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6′-diamino-3,6′-dideoxydi-α-<span class="text-smallcaps">D</span>-glucoside
• 4,6-Diamino-3-[(6-Amino-6-Deoxyhexopyranosyl)Oxy]-2-Hydroxycyclohexyl 3-Amino-3-Deoxyhexopyranoside
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-
• D-Deoxydi
• D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
• D-Streptamine,O-3-Amino-3-Deoxy-Alpha-D-Glucopyranosyl-(1.Fwdarw.6)-O-[6-Amin
• KM
• Kanacin
• Kanamicina
• Kanamycin A
• Kanamycin Base
• Kanamycine
• O-3-Amino-3-deoxy-α-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)]-2-deoxy-<smallcap>D</span>-streptamine
• O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine
• KANAMYCIN
• 1-O-[(1R)-2α-Hydroxy-3β-(3-amino-3-deoxy-α-D-glucopyranosyloxy)-4α,6α-diaminocyclohexane-1β-yl]-6-amino-6-deoxy-α-D-glucopyranose
• km(theantibiotic)
• o-6-deoxy-alpha-d-glucopyranosyl-(1.fwdarw.)]-2-deoxy-
• Kannamycin Monosulfate
• KANAMYCIN BASE ENTERPRISE STANDARD
• KanamycinMonosulfateA
• 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine
• (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-bis(azanyl)-3-[(2S,3R,4S,5S,6R)-4-azanyl-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-oxane-3,4,5-triol
• glucopyranoside,4,6-diamino-2-hydroxy-1,3-cyclohexylene3,6’diamino-3,6’-dideo
• d-xydi
• y-alpha-d-glucopyranosyl-(1-4))-2-deoxy-
• (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol
• (2R,3S,4S,5R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol
• glucopyranoside,4,6-diamino-2-hydroxy-1,3-cyclohexylene3,6’-diamino-3,6’-di
• 6-O-(3-Amino-3-deoxy-α-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine

Kanamycin Monosulfate

CAS: 25389-94-0, 59-01-8, 8063-07-8

Fórmula: C₁₈H₃₆N₄O₁₁·H₂SO₄

Pureza: >94.0%(N)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 582.58

Ref: 3B-K0047

(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol

CAS: 59-01-8

Fórmula: C₁₈H₃₆N₄O₁₁

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 484.4986

Ref: IN-DA01E3XP

Amikacin EP Impurity D

CAS: 59-01-8

Fórmula: C₁₈H₃₆N₄O₁₁

Cor e Forma: White To Off-White Solid

Peso molecular: 484.50

Ref: 4Z-A-144004

Kanamycin A

CAS: 59-01-8

Kanamycin A (KanamycinA) is an aminoglycoside antibiotic with antibacterial and antiviral activity that inhibits bacterial and viral replication.

Fórmula: C₁₈H₃₆N₄O₁₁

Pureza: 99.59%

Cor e Forma: Crystals From Methanol + Ethanol Solid

Peso molecular: 484.5

Ref: TM-T0793L

Kanamycin A

CAS: 59-01-8

Kanamycin A

Pureza: ≥98%

Peso molecular: 484.5g/mol

Ref: 54-BUP17386

KANAMYCIN

CAS: 59-01-8

Pureza: 97%;RG

Cor e Forma: Liquid

Peso molecular: 484.5029907

Ref: 10-F824194

Kanamycin A

CAS: 59-01-8

Inhibitor of protein synthesis; aminoglycoside

Fórmula: C₁₈H₃₆N₄O₁₁

Pureza: Min. 95%

Cor e Forma: White Clear Liquid

Peso molecular: 484.5 g/mol

Ref: 3D-AK30116

Amikacin EP Impurity D

CAS: 59-01-8

Fórmula: C₁₈H₃₆N₄O₁₁

Peso molecular: 484.5

Ref: ST-EA-CP-A190004