CAS 5909-24-0

Etil 4-cloro-2-(metiltio)-5-pirimidinocarboxilato

Descrição:

Etil 4-cloro-2-(metiltio)-5-pirimidinocarboxilato, com o número CAS 5909-24-0, é um composto químico que pertence à classe dos derivados de pirimidina. Apresenta um anel de pirimidina substituído por um grupo cloro na posição 4 e um grupo metiltio na posição 2, juntamente com um grupo funcional de éster etílico na posição do ácido carboxílico. Este composto é tipicamente caracterizado por sua solubilidade moderada a baixa em água, sendo mais solúvel em solventes orgânicos como etanol e diclorometano. Sua estrutura sugere uma potencial atividade biológica, tornando-o de interesse na pesquisa farmacêutica. A presença dos substituintes cloro e metiltio pode influenciar sua reatividade e interação com alvos biológicos. Etil 4-cloro-2-(metiltio)-5-pirimidinocarboxilato pode ser sintetizado através de várias reações orgânicas, e seus derivados podem exibir diversas propriedades farmacológicas, incluindo atividades antimicrobianas ou anti-inflamatórias. O manuseio e armazenamento adequados são essenciais devido à sua natureza química, e as fichas de dados de segurança devem ser consultadas para diretrizes específicas de segurança.

Fórmula: C₈H₉ClN₂O₂S

InChI: InChI=1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3

Chave InChI: InChIKey=SNNHLSHDDGJVDM-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(Cl)=NC(SC)=NC1

Sinónimos:

• 2-Methylthio-4-chloro-5-ethoxycarbonylpyrimidine
• 4-Chloro-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester
• 4-Chloro-2-(methylthio)pyrimidin-5-carboxylic acid ethyl ester
• 4-Chloro-2-Methylthio-5-Pyrimidnecarboxylat
• 4-Chloro-2-methane-sulfanylpyrimidine-5-carboxylic Acid Ethyl Ester
• 4-Chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methanethiopyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylsulfanylpyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylthio-5-carbethoxypyrimidine
• 4-Chloro-5-Ethoxycarbonyl-2-Methylthiopyrimidine
• 4-Chloro-5-carbethoxy-2-methylthiopyrimidine
• 5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-, ethyl ester
• Ethyl 4-Chloro-2-(Methylsulfanyl)Pyrimidine-5-Carboxylate
• Ethyl 4-Chloro2-methylthiopyrimidine-5-carboxylate
• Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
• Ethyl 4-chloro-2-methylsulfanyl-5-pyrimidinecarboxylate
• Ethyl 4-chloro-2-methylthio-5-pyrimidine carboxylate
• Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
• NSC 123534

Ethyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Pureza: >97.0%(GC)

Cor e Forma: White to Orange to Green powder to crystal

Peso molecular: 232.68

Ref: 3B-E0841

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98%

CAS: 5909-24-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₈H₉ClN₂O₂S

Pureza: 98%

Cor e Forma: White to cream, powder

Peso molecular: 232.68

Ref: 02-B22429

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 232.6873

Ref: IN-DA00371D

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

Fórmula: C₈H₉ClN₂O₂S

Pureza: 98%

Cor e Forma: colourless to faint yellow crystalline solid

Peso molecular: 232.69g/mol

Ref: 54-OR6605

Avanafil Impurity 61

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Peso molecular: 232.68

Ref: 4Z-A-2967

Ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 232.68

Ref: 10-F005213

Ethyl 4-Chloro-2-methylthiopyrimidine-5-carboxylate

Produto Controlado

CAS: 5909-24-0

Applications A pyrimidine derivative as inhibitor of Streptococcus faecium, Lactobacillus casei, and Pediococcus cerevisiae.
References Coats, E.A., et al.: Eur. J. Med. Chem., 14, 261 (1979),

Fórmula: C₈H₉ClN₂O₂S

Cor e Forma: Neat

Peso molecular: 232.69

Ref: TR-E902000

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

CAS: 5909-24-0

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate is a potent inhibitor of tyrosine kinases. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug has also been shown to be effective against various types of human cancer cell lines, such as human leukemia cells and myeloma cells. Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate inhibits the production of proteins vital for cell division by binding to tyrosine kinase. This binding prevents the formation of an enzyme complex with other enzymes that are required for protein synthesis, thereby inhibiting protein synthesis and cell division. The compound has also been shown to be a highly selective inhibitor of amines, which may contribute to its pharmacological effects.

Fórmula: C₈H₉ClN₂O₂S

Pureza: Min. 95%

Peso molecular: 232.69 g/mol

Ref: 3D-FE15899

Avanafil Impurity 61

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Peso molecular: 232.68

Ref: ST-EA-CP-A84036