CAS 591-59-3

3-Fosfogliceraldeído

Descrição:

3-Fosfogliceraldeído, também conhecido como gliceraldeído-3-fosfato (G3P), é um fosfato de açúcar de três carbonos que desempenha um papel crucial no metabolismo celular, particularmente na glicólise e no ciclo de Calvin. É um sólido incolor e higroscópico que é solúvel em água. O composto apresenta um grupo funcional aldeído e um grupo fosfato, que contribuem para sua reatividade e importância biológica. G3P é um intermediário importante na conversão de glicose em energia, bem como na síntese de carboidratos e lipídios. Existe em equilíbrio entre sua forma de aldeído e uma forma cíclica de hemiacetal em solução. A molécula também é um composto quiral, com um estereocentro, levando à existência de dois enantiômeros, embora apenas um seja biologicamente ativo. Devido ao seu papel central no metabolismo, 3-Fosfogliceraldeído é vital para a produção de energia e a biossíntese de várias biomoléculas em organismos vivos.

Fórmula: C₃H₇O₆P

InChI: InChI=1S/C3H7O6P/c4-1-3(5)2-9-10(6,7)8/h1,3,5H,2H2,(H2,6,7,8)

Chave InChI: InChIKey=LXJXRIRHZLFYRP-UHFFFAOYSA-N

SMILES: C(C(C=O)O)OP(=O)(O)O

Sinónimos:

• (2-Hydroxy-3-oxopropoxy)phosphonic acid
• 2-Hydroxy-3-(phosphonooxy)propanal
• 3-Phosphoglyceraldehyde
• 3-Phosphoroglyceric aldehyde
• 3-fosfato de DL-gliceraldehido
• 3-phosphate de DL-glyceraldehyde
• <span class="text-smallcaps">DL</span>-Glyceraldehyde 3-phosphate
• DL-Glyceraldehyd-3-phosphat
• DL-glyceraldehyde 3-phosphate
• Glyceraldehyde, 3-(dihydrogen phosphate), <span class="text-smallcaps">DL</span>-
• Glyceraldehyde, 3-(dihydrogen phosphate), DL-
• Phosphoglyceraldehyde

DL-Glyceraldehyde 3-phosphate - 45-55 mg/mL aqueous solution

CAS: 591-59-3

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an enzyme that catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3 bisphosphoglycerate. GAPDH is involved in glycolysis and the pentose phosphate pathway. It has been shown to be an important player in mediating cellular responses to hypoxia, inflammation, and oxidative stress. The glyceraldehyde-3-phosphate dehydrogenase gene has been found to be mutated in a number of cancers including breast cancer and colon cancer. This gene also has a role in inflammatory lesion development as well as energy metabolism. GAPDH also participates in the biochemical reactions that lead to neuronal death during neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Fórmula: C₃H₇O₆P

Cor e Forma: Colorless Clear Liquid

Peso molecular: 170.06 g/mol

Ref: 3D-MG46662

DL-Glyceraldehyde 3-phosphate - 45-55 mg/mL aqueous solution

CAS: 591-59-3

Glyceraldehyde 3-phosphate (G3P) is an intermediate in the glycolytic pathway. It is also a component of polysaccharides and glycosaminoglycans. G3P is synthesized from glucose by the enzyme triose phosphate isomerase. The synthesis of G3P can be achieved by a number of methods, including methylation, fluorination, and click chemistry. This product contains 45-55 mg/mL of Glyceraldehyde 3-phosphate in water solution at pH 7.0 and at a temperature range of 2-8°C.

Fórmula: C₃H₇O₆P

Pureza: Min. 95 Area-%

Peso molecular: 170.06 g/mol

Ref: 3D-G-4125

DL-Glyceraldehyde-3-phosphate

CAS: 591-59-3

DL-Glyceraldehyde-3-phosphate (3-Phosphoglyceraldehyde) inhibits acyltransferases and inhibits the growth of E. coli at high concentrations.

Fórmula: C₃H₇O₆P

Cor e Forma: Solid

Peso molecular: 170.06

Ref: TM-T37521