CAS 59122-46-2
:Misoprostol
Descrição:
Misoprostol é um análogo sintético da prostaglandina E1, utilizado principalmente na medicina por sua capacidade de induzir contrações uterinas e proteger a mucosa gástrica. É caracterizado por sua forma de pó cristalino branco a off-white, que é solúvel em água e em solventes orgânicos como o etanol. Misoprostol atua ligando-se aos receptores de prostaglandina, levando a vários efeitos fisiológicos, incluindo a estimulação de contrações uterinas, amadurecimento cervical e inibição da secreção de ácido gástrico. Suas aplicações terapêuticas incluem a prevenção de úlceras gástricas em pacientes que tomam anti-inflamatórios não esteroides (AINEs), bem como seu uso em obstetrícia e ginecologia para aborto médico e manejo de abortos espontâneos. O composto é tipicamente administrado por via oral ou vaginal, e sua farmacocinética envolve rápida absorção e metabolismo, com uma meia-vida relativamente curta. O perfil de segurança de Misoprostol é geralmente favorável, mas pode causar efeitos colaterais como distúrbios gastrointestinais e hiperestimulação uterina, necessitando de monitoramento cuidadoso durante o uso.
Fórmula:C22H38O5
InChI:InChI=1/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/s2
Chave InChI:InChIKey=OJLOPKGSLYJEMD-YUQTXCCYNA-N
SMILES:C(=C/CC(CCCC)(C)O)\[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O
Sinónimos:- (+-)-Methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
- (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester
- (11alpha,13E)-(+)-11alpha,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester
- (±)-15-Deoxy-(16RS)-16-hydroxy-16-methyl-PGE1 Methyl Ester
- Cytotec
- Isprelor
- Misogon
- Misoprost
- Misoprostil
- Misotac
- Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11α,13E)-
- Sc 29333
- methyl (11alpha,13E)-11-hydroxy-16,16-dimethyl-9-oxoprost-13-en-1-oate
- methyl (11alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
- Ver mais sinónimos
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13 produtos.
MISOPROSTOL FOR SYSTEM SUITABILITY CRS
CAS:<p>MISOPROSTOL FOR SYSTEM SUITABILITY CRS</p>Fórmula:C22H38O5Peso molecular:382.5341Misoprostol
CAS:<p>Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues</p>Fórmula:C22H38O5Cor e Forma:Colorless Light Yellow Liquid ViscousPeso molecular:382.27192Misoprostol
CAS:<p>Misoprostol, a prostaglandin E1 derivative, has a strong inhibitory effect on gastric acid secretion, while having a contractile effect on pregnancy.</p>Fórmula:C22H38O5Pureza:99.78%Cor e Forma:Water-Soluble Viscous LiquidPeso molecular:382.53Misoprostol (0.10% wt/v in METHYL ACETATE), min. 97%
CAS:Fórmula:C22H38O5Pureza:min. 97%Cor e Forma:White to Yellowish Oil (SOLUTION IN 10% METHYL ACETATE)Peso molecular:382.53Misoprostol (Mixture of Diastereomers)
CAS:Fórmula:C22H38O5Cor e Forma:Pale Yellow OilPeso molecular:382.54Misoprostol
CAS:Fórmula:C22H38O5Pureza:≥ 99.0%Cor e Forma:Colourless to light yellow liquidPeso molecular:382.53Misoprostol
CAS:Produto Controlado<p>Applications Misoprostol is a cytoprotective prostaglandin PGE1 analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Graham, Y., et al.: Lancet, 2, 1277 (1988); Graham, D.Y., et al.: Ann. Int. Med., 119, 257 (1993); Fletcher, H., et al.: Obstet. Gynecol., 83, 244 (1994);<br></p>Fórmula:C22H38O5Cor e Forma:Light Yellow ViscousPeso molecular:382.53Misoprostol, 1% in cellulose
CAS:Produto ControladoFórmula:C22H38O5Cor e Forma:Single SolutionPeso molecular:382.53Misoprostol - 1% in cellulose
CAS:Produto Controlado<p>Misoprostol is a nonsteroidal anti-inflammatory drug that is used for the treatment of dysmenorrhea and chronic non-specific low back pain. Misoprostol is also used in nephrology dialysis to decrease blood pressure, heart rate, and fluid retention in patients with congestive heart failure. It has been shown that misoprostol can be used to prevent preterm labor in pregnant women with a statistically significant reduction in the risk of miscarriage, preterm birth, and neonatal death. It has been shown that misoprostol can be administered orally or vaginally for the prevention of preterm labor. The pharmacokinetic properties of misoprostol are dose-dependent; higher doses result in faster absorption. Clinical relevance is dependent on the concentration-time curve, which determines how quickly the drug reaches its peak concentration. The clinical relevance of misoprostol is determined by the dose group (low dose or high dose), as well as diastolic</p>Fórmula:C22H38O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:382.53 g/molMisoprostol
CAS:Produto Controlado<p>Misoprostol is a prostaglandin E1 analogue that is used for the prevention and treatment of peptic ulcers. It also has been shown to reduce the risk of gastric cancer in the general population, although this effect may be limited to patients with a history of nonsteroidal anti-inflammatory drug use. Misoprostol has been found to be more effective in women who have already given birth than in those who have not, with a statistically significant reduction in the incidence of pregnancy during long-term use. Misoprostol is metabolized by cytochrome P450 enzymes and excreted primarily through the kidneys. The drug's pharmacokinetic properties are dependent on diastolic blood pressure, body mass index, and levels of blood sampling. Intrauterine placement can also increase its efficacy as it bypasses first-pass metabolism.</p>Fórmula:C22H38O5Pureza:Min. 95%Cor e Forma:Colorless Clear LiquidPeso molecular:382.53 g/mol
