CAS 59401-28-4

fator de acasalamento alfa(1) de Saccharomyces cerevisiae

Descrição:

O fator de acasalamento alfa(1), também conhecido como alfa-factor, é uma feromona peptídica produzida pela levedura Saccharomyces cerevisiae, especificamente por células do tipo de acasalamento alfa. Esta molécula de sinalização desempenha um papel crucial no processo de acasalamento da levedura, facilitando a comunicação entre diferentes tipos de acasalamento (alfa e a). A estrutura do alfa-factor consiste em uma cadeia curta de aminoácidos, tipicamente composta por cerca de 12 resíduos, que inclui uma estrutura cíclica única que aumenta sua estabilidade e atividade biológica. A feromona se liga a receptores específicos nas células a, desencadeando uma cascata de respostas celulares que levam ao acasalamento e fusão dos dois tipos de células. O alfa-factor também é utilizado em várias aplicações biotecnológicas, incluindo genética de leveduras e processos de fermentação. Seu número CAS, 59401-28-4, identifica-o em bancos de dados químicos, auxiliando na pesquisa e desenvolvimento. No geral, o fator de acasalamento alfa(1) é essencial para o ciclo reprodutivo da levedura e serve como modelo para estudar sinalização celular e comunicação em organismos eucarióticos.

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

InChI: InChI=1/C82H114N20O17S/c1-45(2)34-61(98-76(112)63(38-49-41-89-56-17-9-7-15-53(49)56)99-77(113)64(39-50-42-87-44-91-50)96-71(107)54(84)37-48-40-88-55-16-8-6-14-52(48)55)74(110)93-57(25-27-68(85)104)72(108)97-62(35-46(3)4)75(111)95-59(18-10-11-30-83)80(116)101-31-12-19-66(101)78(114)90-43-70(106)92-60(26-28-69(86)105)81(117)102-32-13-20-67(102)79(115)94-58(29-33-120-5)73(109)100-65(82(118)119)36-47-21-23-51(103)24-22-47/h6-9,14-17,21-24,40-42,44-46,54,57-67,88-89,103H,10-13,18-20,25-39,43,83-84H2,1-5H3,(H2,85,104)(H2,86,105)(H,87,91)(H,90,114)(H,92,106)(H,93,110)(H,94,115)(H,95,111)(H,96,107)(H,97,108)(H,98,112)(H,99,113)(H,100,109)(H,118,119)/t54-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(C)C)C(=N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=NCC(=N[C@@H](CCC(=N)O)C(=O)N1CCC[C@H]1C(=N[C@@H](CCSC)C(=N[C@@H](Cc1ccc(cc1)O)C(=O)O)O)O)O)O)O)O)O)N=C([C@H](Cc1c[nH]c2ccccc12)N=C([C@H](Cc1cnc[nH]1)N=C([C@H](Cc1c[nH]c2ccccc12)N)O)O)O

Sinónimos:

• H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH
• Mating Factor .alpha.
• a-Mating Factor, Yeast
• alpha1-Mating factor Saccharomyces cerevisiae
• L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine
• Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

α-Mating Factor, yeast

CAS: 59401-28-4

alpha-Mating Factor, yeast

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

Peso molecular: 1684.2

Ref: 02-J66502

Mating Factor α

CAS: 59401-28-4

Mating pheromone of mating type α cells of S. cerevisiae. This factor inhibits DNA synthesis, thereby preventing cell division of mating type a cells. The hydrophobic peptide binds to a class D G-protein-coupled receptor Ste2p.

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

Pureza: 98.4%

Cor e Forma: White Powder

Peso molecular: 1684.01

Ref: 01-4003514

L-Tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine

CAS: 59401-28-4

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

Pureza: 98%

Peso molecular: 1683.9714

Ref: IN-DA01EO0Y

α-Factor Mating Pheromone, yeast

CAS: 59401-28-4

Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

Pureza: 98%

Cor e Forma: White Powder

Peso molecular: 1684

Ref: TM-TP1106

Alpha-Mating Factor

CAS: 59401-28-4

Alpha-Mating Factor is a peptide that belongs to the group of ligands. It has been shown to bind to the androgen receptor with high affinity and act as an activator for this receptor. Alpha-Mating Factor is also able to bind to the beta-adrenergic receptor. This protein has been shown to have ion channel activity, which may be due to its inhibition of potassium channels. Alpha-Mating Factor is used in research as a tool for studying cell biology and cell signalling pathways.

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

Pureza: Min. 95%

Peso molecular: 1,684 g/mol

Ref: 3D-PMF-4076-V

Alpha-Factor

CAS: 59401-28-4

The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle, this allows the opposite mating type cells to synchronise. Alpha factor mating pheromone induces the expression of mating genes, changes in nuclear architecture, and polarizes growth toward the mating partner. STE2 encodes the alpha factor pheromone transmembrane G-protein coupled receptor (GPCR) found on mating-type-A cells in yeast. Alpha factor binds Ste2 and activates prototypic mitogen-activated protein kinase (MAPK) cascade. The dose of pheromone exposure differentially activates the MAPK Fus3 for alternate effects. A high dose of alpha factor leads to growth arrest and schmooing formation for mating, a lower dose causes elongated cell growth.

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 1,683.97 g/mol

Ref: 3D-CRB1000148

Mating Factor a trifluoroacetate salt

CAS: 59401-28-4

Please enquire for more information about Mating Factor a trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S·xC₂HF₃O₂

Pureza: Min. 95%

Peso molecular: 1,683.97 g/mol

Ref: 3D-FM108804

Mating factor α trifluoroacetate

CAS: 59401-28-4

Mating factor α trifluoroacetate is a research tool with CAS No. 59401-28-4 that is used in Cell Biology, Pharmacology, and Ion channels. Mating factor α trifluoroacetate inhibits ligand binding to receptor by competing with the natural substrate for the active site. It has been shown to be an activator of ion channels, which allow ions to flow through the cell membrane. Mating factor α trifluoroacetate can also be used as a research tool in antibody production and protein interactions.

Fórmula: C₈₂H₁₁₄N₂₀O₁₇S

Pureza: Min. 95%

Peso molecular: 1,684.01 g/mol

Ref: 3D-JCA40128