CAS 59880-97-6

N-Formil-L-metionil-L-leucil-L-fenilalanina

Descrição:

N-Formil-L-metionil-L-leucil-L-fenilalanina, com o número CAS 59880-97-6, é um peptídeo sintético que consiste em três aminoácidos: metionina, leucina e fenilalanina, com um grupo formilo ligado ao terminal amino do resíduo de metionina. Este composto é caracterizado por sua sequência específica de aminoácidos, que contribui à sua atividade biológica e potenciais aplicações em pesquisa bioquímica. Peptídeos como este frequentemente exibem propriedades como solubilidade em solventes polares, estabilidade em condições fisiológicas e a capacidade de interagir com receptores biológicos ou enzimas. A presença do grupo formilo pode influenciar a reatividade do peptídeo e seu papel em várias vias bioquímicas. N-Formil-L-metionil-L-leucil-L-fenilalanina também pode servir como um composto modelo para estudar a síntese de peptídeos, relações estrutura-atividade e os mecanismos de sinalização mediada por peptídeos em sistemas biológicos. Sua estrutura única o torna um assunto de interesse em campos como química medicinal e farmacologia.

Fórmula: C₈H₁₂ClNO

InChI: InChI=1/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1

Chave InChI: InChIKey=PRQROPMIIGLWRP-BZSNNMDCSA-N

SMILES: [C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)(NC([C@H](CCSC)NC=O)=O)CC(C)C

Sinónimos:

• 3: PN: WO2010089019 PAGE: 22 claimed protein
• 4-(2-Aminoethyl)Phenol Hydrochloride (1:1)
• 4-Hydroxy-phenethylamine hydrochloride
• <span class="text-smallcaps">L</smallcap>-Phenylalanine, N-[N-(N-formyl-<smallcap>L</smallcap>-methionyl)-<smallcap>L</span>-leucyl]-
• <span class="text-smallcaps">L</smallcap>-Phenylalanine, N-formyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</span>-leucyl-
• For-Met-Leu-Phe-OH
• Formyl-Met-Leu-Phe-OH
• N-Formyl-<span class="text-smallcaps">L</smallcap>-methionyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-phenylalanine
• N-Formyl-Met-Leu-Phe
• N-Formyl-Met-Leu-Phe-OH
• N-Formyl-methionyl-leucyl-phenylalanine
• N-formylmethionylleucylphenylalanine
• NSC 350593
• L-Phenylalanine, N-formyl-L-methionyl-L-leucyl-
• L-Phenylalanine, N-[N-(N-formyl-L-methionyl)-L-leucyl]-
• N-Formyl-L-methionyl-L-leucyl-L-phenylalanine
• fMLF
• 4-HYDROXYPHENYLETHYLAMINE HCL
• 4-HYDROXYPHENETHYLAMINE HYDROCHLORIDE
• fMLP (misnomer but widely used)
• F-MET-LEU-PHE
• TYRAMINE MONOHYDROCHLORIDE
• 4-(2-AMINOETHYL)PHENOL HYDROCHLORIDE
• P-HYDROXYPHENETHYLAMINE HYDROCHLORIDE
• TYRAMINE HCL(P)
• TYRAMINE HCL
• TIMTEC-BB SBB003808
• P-(2-AMINOETHYL)PHENOL HYDROCHLORIDE
• 2-(4-HYDROXYPHENYL)ETHYLAMMONIUM CHLORIDE
• TYROSAMINE HCL
• TYROSAMINE HYDROCHLORIDE
• TYRAMINE
• 2-(4-HYDROXYPHENYL)ETHYLAMINE HYDROCHLORIDE
• 4-HYDROXYPHENYLETHYLAMINE HYDROCHLORIDE
• 2-(4-HYDROXYPHENYL)ETHYLAMINE HCL

N-Formyl-L-methionyl-L-leucyl-L-phenylalanine

CAS: 59880-97-6

Fórmula: C₂₁H₃₁N₃O₅S

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 437.56

Ref: 3B-F1158

Chemotactic Peptide

CAS: 59880-97-6

For cellular and molecular biology applications

Fórmula: C₂₁H₃₁N₃O₅S

Cor e Forma: White to pale cream, Lyophilized Powder

Peso molecular: 437.56

Ref: 02-J65184

For-Met-Leu-Phe-OH

CAS: 59880-97-6

There is evidence that pretreatment of human polymorphonuclear neutrophils (PMN) with fMLF results in the inhibition of TNF-α secretion, which indicates that this typical proinflammatory agent could play, at least at determined conditions, an antiinflammatory role.

Fórmula: C₂₁H₃₁N₃O₅S

Pureza: 99.7%

Cor e Forma: White Powder

Peso molecular: 437.56

Ref: 01-4001509

TYRAMINE HYDROCHLORIDE

CAS: 59880-97-6

Fórmula: C₂₁H₃₁N₃O₅S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 437.5529

Ref: IN-DA00E9MC

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

N-Formyl-Met-Leu-Phe

Pureza: ≥95%

Peso molecular: 437.55g/mol

Ref: 54-BUP06404

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

Fórmula: C₂₁H₃₁N₃O₅S

Peso molecular: 437.55

Ref: 7W-GL6160

N-formyl-[U-13C-15N]-Met-Leu-Phe-OH

CAS: 59880-97-6

N-formyl-[U-13C-15N]-Met-Leu-Phe-OH

Pureza: 98%

Peso molecular: 437.55g/mol

Ref: 54-OR1023295

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).

Fórmula: C₂₁H₃₁N₃O₅S

Pureza: 98.69% - ≥95%

Cor e Forma: Solid

Peso molecular: 437.55

Ref: TM-T7091

Chemotactic Peptide

CAS: 59880-97-6

As a chemotactic peptide, For-Met-Leu-Phe (FMLP) has chemotactic properties, which means it can attract cells. For example it is a chemoattractant for phagocytic leukocytes and neutrophils. Neutrophils which have seven transmembrane G-protein coupled receptors are activated during the acute inflammatory response by FMLP and other chemotactic factors which bind to its surface receptors. This results in the activate of NF- κB, MAPK and PI3K pathways. In particular FMLP is known to induce Interleukin-8 (IL-8) which is responsible for both tissue damage and the pathogenesis of inflammatory processes resulting from neutrophils. Chemotactic peptide have been used to study the function of polymorphonuclear leukocytes and other white blood cells in inflammation. Chemotactic peptides are often used as fluorescent probes to measure intracellular metabolic responses to chemoattractant stimulation.
This product is available as a 0.5mg vial.

Fórmula: C₂₁H₃₁N₃O₅S

Pureza: Min. 95%

Peso molecular: 437.55 g/mol

Ref: 3D-PCT-4066-V

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₂₁H₃₁N₃O₅S

Peso molecular: 437.6 g/mol

Ref: 3D-PP50655

N-Formyl-Met-Leu-Phe

Produto Controlado

CAS: 59880-97-6

Applications N-Formyl-Met-Leu-Phe is an inducer of superoxide release and agonist for FPR1.

Fórmula: C₂₁H₃₁N₃O₅S

Cor e Forma: Neat

Peso molecular: 437.55

Ref: TR-F700713

Chemotactic Peptide

CAS: 59880-97-6

Chemotactic peptides are peptides that possess chemotactic properties, which means they attract cells. One well-known chemotactic peptide is For-Met-Leu-Phe (FMLP) and is a chemoattractant for phagocytic leukocytes and neutrophils. During the acute inflammatory response chemotactic factors activate neutrophils which have seven transmembrane G-protein coupled receptors. FMLP bind to these G-protein coupled receptors on the surface of neutrophils and activate NF- κB, MAPK and PI3K pathways. In particular FMLP is known to induce Interleukin-8 (IL-8) which is responsible for both tissue damage and the pathogenesis of inflammatory processes resulting from neutrophils. Chemotactic peptide have been used to study the function of polymorphonuclear leukocytes and other white blood cells in inflammation. Chemotactic peptides are often used as fluorescent probes to measure intracellular metabolic responses to chemoattractant stimulation.

Fórmula: C₂₁H₃₁N₃O₅S

Pureza: Min. 95%

Peso molecular: 437.55 g/mol

Ref: 3D-PCT-4066