CAS 59887-17-1

B-endorfina bovina

Descrição:

B-endorfina bovina, com o número CAS 59887-17-1, é um peptídeo que pertence à família das endorfinas, que são neuropeptídeos opioides endógenos. É produzido principalmente na glândula pituitária e desempenha um papel crucial na modulação da dor, na resposta ao estresse e na regulação do humor. A B-endorfinas é composta por 31 aminoácidos e é conhecida por sua capacidade de se ligar aos receptores opioides no cérebro, levando a efeitos analgésicos e sensações de euforia. Este peptídeo é altamente conservado entre espécies, com a B-endorfinas bovina sendo semelhante à sua contraparte humana. Em termos de propriedades físicas, geralmente é um pó branco a off-white que é solúvel em água, tornando-o adequado para várias aplicações bioquímicas. A atividade biológica da B-endorfinas é significativa em pesquisas relacionadas ao manejo da dor, dependência e transtornos de saúde mental. Sua estabilidade e eficácia podem ser influenciadas por fatores como pH e temperatura, que são considerações importantes em ambientes de laboratório.

Fórmula: C₁₅₅H₂₅₀N₄₂O₄₄S

InChI: InChI=1/C155H250N42O44S/c1-17-82(9)123(150(235)182-99(44-29-34-61-160)134(219)186-109(70-116(164)206)139(224)171-84(11)128(213)183-108(69-92-72-166-78-170-92)144(229)178-96(41-26-31-58-157)132(217)175-95(40-25-30-57-156)131(216)169-75-120(210)173-103(155(240)241)51-54-115(163)205)193-151(236)124(83(10)18-2)192-129(214)85(12)172-140(225)110(71-117(165)207)185-133(218)97(42-27-32-59-158)177-143(228)107(68-90-38-23-20-24-39-90)184-141(226)104(64-79(3)4)188-152(237)126(87(14)201)195-149(234)122(81(7)8)191-145(230)105(65-80(5)6)187-148(233)113-45-35-62-197(113)154(239)127(88(15)202)196-137(222)100(50-53-114(162)204)179-146(231)111(76-198)189-135(220)98(43-28-33-60-159)176-136(221)101(52-55-121(211)212)180-147(232)112(77-199)190-153(238)125(86(13)200)194-138(223)102(56-63-242-16)181-142(227)106(67-89-36-21-19-22-37-89)174-119(209)74-167-118(208)73-168-130(215)94(161)66-91-46-48-93(203)49-47-91/h19-24,36-39,46-49,72,78-88,94-113,122-127,198-203H,17-18,25-35,40-45,50-71,73-77,156-161H2,1-16H3,(H2,162,204)(H2,163,205)(H2,164,206)(H2,165,207)(H,166,170)(H,167,208)(H,168,215)(H,169,216)(H,171,224)(H,172,225)(H,173,210)(H,174,209)(H,175,217)(H,176,221)(H,177,228)(H,178,229)(H,179,231)(H,180,232)(H,181,227)(H,182,235)(H,183,213)(H,184,226)(H,185,218)(H,186,219)(H,187,233)(H,188,237)(H,189,220)(H,190,238)(H,191,230)(H,192,214)(H,193,236)(H,194,223)(H,195,234)(H,196,222)(H,211,212)(H,240,241)/t82-,83-,84-,85-,86+,87+,88+,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,123-,124-,125-,126-,127-/m0/s1

Sinónimos:

• beta-Endorphin (1-31)
• beta-Endorphin, triethoxy(3-isothiocyanatopropyl)-, (6R-(6alpha,7alpha,7(R*)))-

Beta-Endorphin (rat)

CAS: 59887-17-1

Beta-endorphin is a basic protein that is an endogenous opioid peptide hormone with potent analgesic effects. Beta-endorphin binds to the kappa-opioid receptor, which inhibits the production of inflammatory cytokines IL-2 and TNF-α in activated macrophages. Beta-endorphin has been shown to have potent inducers of cardiac contractility and vasodilation when administered intravenously to rats. It also binds to the dextran sulfate receptor and can cause vasoconstriction in rat aorta. In addition, beta-endorphin has been shown to be an inhibitor of pluripotent cells, which are cells that have the ability to differentiate into any type of cell. This inhibition may be due to its binding to basic proteins or its effects on the synthesis of peptide hormones such as prolactin or growth hormone.

Fórmula: C₁₅₇H₂₅₄N₄₂O₄₄S

Pureza: Min. 95%

Peso molecular: 3,466.02 g/mol

Ref: 3D-FE108786

Beta-Endorphin (bovine, camel, mouse)

CAS: 59887-17-1

Beta-Endorphin (β-EP) is a peptide hormone that has a number of biological properties. It binds to kappa opioid receptors and affects the function of various cells in the body. β-EP is also potent inducers of pluripotent stem cells and has been shown to reduce pain and inflammation, as well as having anti-inflammatory properties. β-EP may also have some physiological effects on the brain, including increasing blood flow to the brain, affecting memory, and reducing stress levels.

Fórmula: C₁₅₅H₂₅₀N₄₂O₄₄S

Pureza: Min. 95%

Peso molecular: 3,437.97 g/mol

Ref: 3D-FE108751

β-Endorphin (bovine, camel, mouse)

CAS: 59887-17-1

Bachem ID: 4007396.

Fórmula: C₁₅₅H₂₅₀N₄₂O₄₄S

Pureza: 90.8%

Cor e Forma: White Powder

Peso molecular: 3438.01

Ref: 01-4007396