CAS 60-54-8

(-)-Tetraciclina

Descrição:

(-)-Tetraciclina é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, caracterizado por sua capacidade de inibir a síntese de proteínas bacterianas. É derivado da bactéria Streptomyces aureofaciens e é conhecido por sua eficácia contra uma ampla gama de bactérias gram-positivas e gram-negativas. A estrutura química de (-)-Tetraciclina apresenta um sistema de quatro anéis com múltiplos grupos funcionais, incluindo grupos hidroxila e dimetilamina, que contribuem para sua solubilidade e atividade biológica. Este composto exibe propriedades como boa biodisponibilidade oral e uma meia-vida relativamente longa, permitindo regimes de tratamento eficazes. (-)-Tetraciclina também é conhecido por seus potenciais efeitos colaterais, incluindo distúrbios gastrointestinais e fotossensibilidade. Além disso, tem sido utilizado em várias aplicações além da medicina humana, incluindo medicina veterinária e agricultura, particularmente no tratamento de infecções e como promotor de crescimento em gado. Seu mecanismo de ação envolve principalmente a ligação à subunidade ribossômica 30S, impedindo assim a ligação de aminoacil-tRNA e inibindo a síntese de proteínas nas bactérias.

Fórmula: C₂₂H₂₄N₂O₈

InChI: InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

Chave InChI: InChIKey=OFVLGDICTFRJMM-WESIUVDSSA-N

SMILES: O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H]

Sinónimos:

• (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
• (4S,4aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α,4aα,5aα,6β,12aα)]-
• 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 6-Methyl-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
• Abramycin
• Achromycin
• Achromycin (naphthacene derivative)
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• Actisite
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• Akne-Pyodron
• Akne-Pyodron Kur
• Ambramicina
• Ambramycin
• Apo-Tetra
• Arcanacycline
• Bio-Tetra
• Biocycline
• Britaciclina
• Calociclina
• Ciclibion
• Cyclomycin
• Cytome
• Deschlorobiomycin
• Dispatetrin
• Economycin
• Enterocycline
• Florocycline
• Gammatet
• Ibicyn
• Kinciclina
• Latycin
• Limecycline
• Medocycline
• Mericycline
• Micycline
• Neocycline
• NorTet
• Novo-Tetra
• Nsc 108579
• Nu-Tetra
• Omegamycin
• Orlycycline
• Panmycin
• Polycycline
• Polycycline (antibiotic)
• Quimocyclin N
• Quimpe Antibiotico
• Resteclin
• Retet
• Robitet Robicaps
• Roviciclina
• Sagittacin N
• Servitet
• Spaciclina
• Steclin V
• Sumycin syrup
• Tetra Hubber
• Tetra-Co
• Tetra-Proter
• Tetrabioptal
• Tetracap
• Tetraciclina
• Tetracitro S
• Tetracyclin
• Tetracycline Base
• Tetracycline Free Base
• Tetradecin
• Tetrafil
• Tetrafosammina
• Tetralan
• Tetralen
• Tetramig
• Tetramykoin
• Tetraseptine
• Triphacycline
• Veracin

Tetracycline Hydrochloride

CAS: 60-54-8, 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: >98.0%(T)

Cor e Forma: Light yellow to Amber to Dark green powder to crystal

Peso molecular: 480.90

Ref: 3B-T2525

Tetracycline

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Pureza: >95.0%(T)(HPLC)

Cor e Forma: Light yellow to Yellow powder to crystal

Peso molecular: 444.44

Ref: 3B-T3971

Tetracycline

CAS: 60-54-8

Tetracycline, 60-54-8, is a broad-spectrum napthacene antibiotic which inhibits bacterial protein synthesis by binding the 30S ribosomal subunit. Learn more.

Fórmula: C₂₂H₂₄N₂O₈

Cor e Forma: Yellow to orange to brown, Crystalline powder or powder

Peso molecular: 444.44

Ref: 02-J61714

Tetracycline

CAS: 60-54-8

Tetracycline (Tetracyclin) is a broad-spectrum antibiotic. Tetracycline is commonly used in anti-infective studies. Cost-effective and quality-assured.

Fórmula: C₂₂H₂₄N₂O₈

Pureza: 92.65% - 98.18%

Cor e Forma: Light Yellow Crystal

Peso molecular: 444.43

Ref: TM-T0912L

(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 444.4346

Ref: IN-DA003UNG

Tetracycline, EP grade

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Pureza: 88.0 - 102.0 % (dried basis)

Cor e Forma: Yellow crystalline powder

Peso molecular: 444.43

Ref: 7W-GA0548

Tetracycline

CAS: 60-54-8

Tetracycline

Pureza: ≥80%

Peso molecular: 444.43g/mol

Ref: 54-BUP17381

Tetracycline-13C2-d6 (Oxytetracycline EP Impurity B-13C2-d6)

CAS: 60-54-8

Fórmula: C₂₀₁₃C₂H₁₈D₆N₂O₈

Peso molecular: 452.46

Ref: 4Z-T-4027

Tetracycline base

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈·xH₂O

Pureza: ≥ 91.0%

Cor e Forma: Light-yellow to dark yellow powder

Peso molecular: 444.43 (anhydrous)

Ref: 7W-GA9779

Tetracycline 13C22,15N2 dried down 2.5 µg/mL

Produto Controlado

CAS: 60-54-8

Fórmula: C₂₂H₂₄₁₅N₂O₈

Cor e Forma: Single Solution

Peso molecular: 468.26

Ref: 04-S17396147DD-2.5

Tetracycline dried down 2.5 µg/mL

Produto Controlado

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Cor e Forma: Single Solution

Peso molecular: 444.43

Ref: 04-A17396145DD-2.5

Tetracycline (Oxytetracycline EP Impurity B)

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Peso molecular: 444.45

Ref: 4Z-T-4030

Tetracycline

CAS: 60-54-8

Impurity Oxytetracycline Hydrochloride EP Impurity B
Applications Tetracycline is a compound that has been shown to induce apoptosis in various cells. Tetracycline was a useful compound to study drug resistance of pathogens of infections in patients with severe liver disease.
References Yao, L., et al.: Zhongguo Linchuang Yanjiu, 29, 1510 (2016)

Fórmula: C₂₂H₂₄N₂O₈

Cor e Forma: Yellow

Peso molecular: 444.43

Ref: TR-T291413

Tetracycline - Bio-X ™

CAS: 60-54-8

Tetracycline is a broad-spectrum antibiotic that is effective against a variety of bacterial infections. It is a polyketide antibiotic that inhibits protein synthesis by binding to ribosomes and preventing the attachment of amino acids to tRNA molecules thus inhibiting bacterial growth.

Fórmula: C₂₂H₂₄N₂O₈

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 444.43 g/mol

Ref: 3D-BT166207

Tetracycline

CAS: 60-54-8

Antibiotic of tetracycline class; protein synthesis inhibitor

Fórmula: C₂₂H₂₄N₂O₈

Pureza: Min. 91 Area-%

Cor e Forma: Powder

Peso molecular: 444.43 g/mol

Ref: 3D-AT35208

(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-6,10,12,12a-tetrahydroxy-6-methyl-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboxamide

CAS: 60-54-8

Pureza: 96%

Peso molecular: 444.4400024

Ref: 10-F862906

Lymecycline EP Impurity H

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Peso molecular: 444.44

Ref: ST-EA-CP-L64008

Tetracycline-d6

CAS: 60-54-8

Tetracycline-d6 is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit. Tetracycline-d6 is used in the treatment of urinary infections caused by E. coli, Enterobacter cloacae, Klebsiella pneumoniae, and Proteus mirabilis. Tetracycline-d6 has been shown to have antimicrobial activity against a wide range of microorganisms including gram negative and gram positive bacteria, as well as fungi and protozoa. It has been shown to be active against methicillin resistant strains such as S. aureus (MRSA), with an antibacterial efficacy comparable to that of erythromycin. The tetracycline resistance gene is located on plasmids and can be transferred between bacterial cells through conjugation or transduction. Tetracycline-d6 is often used in combination with beta lactam antibiotics such as pen

Pureza: Min. 95%

Ref: 3D-FT180092