CAS 60-80-0

Antipirina

Descrição:

Antipirina, com o número CAS 60-80-0, é um composto orgânico pertencente à classe dos pirazolonas. É caracterizado por sua aparência cristalina de branco a amarelo pálido e é conhecido por suas propriedades analgésicas, antipiréticas e anti-inflamatórias. Antipirina tem uma fórmula molecular de C11H12N2O e um peso molecular de aproximadamente 188,23 g/mol. É solúvel em solventes orgânicos como etanol e clorofórmio, mas tem solubilidade limitada em água. Antipirina atua inibindo a produção de prostaglandinas, que são mediadores da dor e da febre. Historicamente, tem sido utilizado em várias aplicações médicas, incluindo alívio da dor e redução da febre, embora seu uso tenha diminuído com o advento de medicamentos mais novos. Além disso, Antipirina às vezes é empregado em estudos farmacocinéticos para avaliar a função hepática devido ao seu metabolismo no fígado. As considerações de segurança incluem potenciais efeitos colaterais, como reações alérgicas e distúrbios hematológicos, exigindo monitoramento cuidadoso durante o uso.

Fórmula: C₁₁H₁₂N₂O

InChI: InChI: 1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

Chave InChI: InChIKey=VEQOALNAAJBPNY-UHFFFAOYSA-N

SMILES: CN1N(C(=O)C=C1C)C2=CC=CC=C2

Sinónimos:

• 1,2-Dihydro-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One
• 1,5-Dimethyl-2-Phenyl-Pyrazolidin-3-One
• 1,5-Dimethyl-2-phenyl-1,2-dihydropyrazol-3-one
• 1,5-Dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
• 1,5-Dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
• 1,5-Dimethyl-2-phenylpyrazol-3-one
• 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
• 1-Phenyl-2,3-dimethyl-5-pyrazolone
• 2,3-Dimethyl-1-phenyl-3-pyrazolin-3-one
• 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one
• 2,3-Dimethyl-1-phenyl-5-pyrazolone
• 2-Phenyl-1,5-dimethyl-3-pyrazolone
• 3H-Pyrazol-3-One, 1,2-Dihydro-1,5-Dimethyl-2- Phenyl-
• Analgesin
• Analgesine
• Anodynin
• Anodynine
• Antipirin
• Antipyrene
• Antipyrin
• Antipyrine,(2,3-Dimethyl-1-phenyl-3-pyr
• Antypirine
• Apirelina
• Apyretine
• Azophen
• Azophene
• Dentigoa N
• Dimethyloxychinizin
• Dimethyloxyquinazine
• Eu-Med mono
• Fenazona
• Fenazone
• Methozin
• Nsc 7945
• Oxydimethylquinazine
• Parodyne
• Phenazon
• Phenazone
• Phenazone (pharmaceutical)
• Phenylon
• Phenylone
• Pyrazophyl
• Sedatin
• Sedatine
• antipyrin(R)
• Antipyrine
• 1,5-DIMETHYL-2-PHENYL-3-PYRAZOLONE
• 1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
• 1,5-Dimethyl1-2-phenyl-3-pyrazolone
• 1-Phenyl-2,3-dimethylpyrazole-5-one
• PHENAZONUM
• 1,2-dihydro-1,5-dimethyl-2-phenyl-3h-pyrazol-3-on
• 1-PHENYL-2,3-DIMETHYLPYRAZOL-5-ONE
• OXYDIMETHYLQUINIZINE
• AURORA KA-3852

Antipyrine

CAS: 60-80-0

Fórmula: C₁₁H₁₂N₂O

Pureza: >99.0%(GC)(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 188.23

Ref: 3B-D1876

Antipyrine, 98%

CAS: 60-80-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₁H₁₂N₂O

Pureza: 98%

Cor e Forma: White, Crystals or powder or crystalline powder

Peso molecular: 188.23

Ref: 02-A11089

Phenazone

CAS: 60-80-0

Cor e Forma: Neat

Ref: 61-FOR0036.05

PHENAZONE CRS

CAS: 60-80-0

PHENAZONE CRS

Fórmula: C₁₁H₁₂N₂O

Cor e Forma: Crystalline Powder. White. Colourless Crystals. Powder.

Peso molecular: 188.2258

Ref: 41-P0800000

Antipyrine

CAS: 60-80-0

Phenazone (antipyrine) and its derivatives

Fórmula: C₁₁H₁₂N₂O

Cor e Forma: Powder

Peso molecular: 188.09496

Ref: 45-1040005

3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl-

CAS: 60-80-0

Fórmula: C₁₁H₁₂N₂O

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 188.2258

Ref: IN-DA00IAN3

Antipyrine

CAS: 60-80-0

Antipyrine, an analgesic/antipyretic, used orally or as ear drops, tests liver enzyme response to diseases/drugs.

Fórmula: C₁₁H₁₂N₂O

Pureza: 99.77%

Cor e Forma: Solid

Peso molecular: 188.23

Ref: TM-T0734

Antipyrine

CAS: 60-80-0

Antipyrine

Pureza: ≥98%

Peso molecular: 188.23g/mol

Ref: 54-BUP19594

Propyphenazone EP Impurity A (Phenazone)

CAS: 60-80-0

Fórmula: C₁₁H₁₂N₃O

Cor e Forma: White To Off-White Solid

Peso molecular: 188.23

Ref: 4Z-P-177001

Phenazone

CAS: 60-80-0

Fórmula: C₁₁H₁₂N₂O

Cor e Forma: Neat

Peso molecular: 188.23

Ref: 04-C16003100

Phenazone

CAS: 60-80-0

Cor e Forma: Neat

Ref: 86-MM0036.05

Antipyrine

CAS: 60-80-0

Applications Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
References Gong H et al. Water Res. 2017 Apr 1;112:167-175Quintão NL et al. Anesth Analg. 2010 Mar 1;110(3):942-50Farrell GC et al. Br J Clin Pharmacol. 1984 Oct;18(4):559-65.

Fórmula: C₁₁H₁₂N₂O

Cor e Forma: White

Peso molecular: 188.23

Ref: TR-A697500

1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one

CAS: 60-80-0

1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one (1,2DHDP) is a chemical inhibitor that prevents the activity of enzymes by binding to their active site. 1,2DHDP has been shown to inhibit the enzyme pyrazole ring synthesis in rat liver microsomes. It also inhibits the production of antimicrobial agents and has been used as a sample preparation agent. 1,2DHDP also interferes with drug interactions by inhibiting cytochrome P450 enzymes in the liver. This compound can be used for wastewater treatment because it is not toxic to bacteria or plants. The mechanism of this inhibitor is unknown but may be due to its ability to bind to the dinucleotide phosphate cofactor at the active site of an enzyme.

Fórmula: C₁₁H₁₂N₂O

Pureza: Min. 95%

Cor e Forma: White/Off-White Solid

Peso molecular: 188.23 g/mol

Ref: 3D-FD75059

1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one

CAS: 60-80-0

Fórmula: C₁₁H₁₂N₂O

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 188.23

Ref: 10-F358184