CAS 61-76-7

Cloridrato de (-)-fenilefrina

Descrição:

Cloridrato de (-)-fenilefrina é uma amina simpaticomimética sintética utilizada principalmente como descongestionante e vasopressor. É caracterizada pela sua capacidade de estimular seletivamente os receptores adrenérgicos alfa-1, levando à vasoconstrição e ao aumento da pressão arterial. Este composto é tipicamente apresentado como um pó cristalino branco a off-white, solúvel em água e álcool, o que facilita seu uso em várias formulações farmacêuticas. A fórmula molecular de Cloridrato de (-)-fenilefrina é C9H13NO2·HCl, e possui um peso molecular que reflete seus componentes estruturais, incluindo um grupo fenólico e uma cadeia lateral de etilamina. Sua estereoquímica é significativa, pois o enantiômero (-) é a forma ativa responsável por seus efeitos terapêuticos. Comumente encontrado em medicamentos de venda livre, é utilizado para aliviar a congestão nasal e como agente midriático em oftalmologia. No entanto, é essencial monitorar seu uso devido a potenciais efeitos colaterais, incluindo hipertensão e bradicardia reflexa, particularmente em populações sensíveis.

Fórmula: C₉H₁₃NO₂·ClH

InChI: InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

Chave InChI: InChIKey=OCYSGIYOVXAGKQ-FVGYRXGTSA-N

SMILES: [C@@H](CNC)(O)C1=CC(O)=CC=C1.Cl

Sinónimos:

• (-)-α-Hydroxy-β-(methylamino)ethyl-α-(3-hydroxybenzene)hydrochloride
• (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• (R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride
• (R)-3-Hydroxy-[α-(methylamino)methyl]benzene methanol hydrochloride
• (R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• (R)-Phenylephrine hydrochloride
• 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• Adrianol
• Ak-Dilate
• Ak-Nefrin
• Alcon Efrin
• Almefrin
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1), (αR)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (R)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (αR)-
• Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (-)-
• D-(-)-Phenylephrinehydrochloride
• Decadron
• Fenilefrina, Clorhidrato
• Irifrin
• Isophrin
• Isophrin hydrochloride
• Levophenylephrine hydrochloride
• Lexatol
• M-Sympatol
• Meta-Sympatol
• Meta-Synephrine hydrochloride
• Metaoxedrine chloride
• Metaoxedrine hydrochloride
• Mydfrin
• Neo-Synephrine hydrochloride
• Neo-Synesin 1
• Neophryn
• Neosinesine
• Nostril
• Oftalfrine
• Phenylephrine HCL
• Phenylephrine Hydrochloride
• Phenylephrine, chlorhydrate
• Phenylephrinhydrochlorid
• Prefrin
• Pyracort D
• R-(-)-m-Synephrine hydrochloride
• Sucraphen
• Synasal
• l-1-(m-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• l-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride
• l-α-Hydroxy-β-methylamino-3-hydroxy-1-ethylbenzene hydrochloride

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystaline

Peso molecular: 203.67

Ref: 3B-P0398

Phenylephrine Hydrochloride

CAS: 61-76-7

Cor e Forma: Neat

Ref: 61-FOR0081.00

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride

Fórmula: C₉H₁₃NO₂HCl

Pureza: 100.0%

Cor e Forma: White

Peso molecular: 203.07131

Ref: 47-284

PHENYLEPHRINE HYDROCHLORIDE CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE CRS

Ref: 41-P1250000

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

Fórmula: C₉H₁₄ClNO₂

Peso molecular: 203.666

Ref: 41-Y0000683

Phenylephrine Hydrochloride

CAS: 61-76-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Fórmula: C₉H₁₃NO₂·ClH

Cor e Forma: White Off-White Crystalline Powder

Peso molecular: 203.07131

Ref: 45-1533002

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride (NCI-c55641) is a selective agonist of the α1-adrenergic receptor.

Fórmula: C₉H₁₄ClNO₂

Pureza: 99.51% - 99.97%

Cor e Forma: Physical Description Odorless White Microcrystalline Powder Bitter Taste Ph (1%

Peso molecular: 203.67

Ref: TM-T0453

(R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₄ClNO₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 203.6660

Ref: IN-DA00IAS9

Phenylephrine HCl

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 167.21 36.46

Ref: 4Z-P-2624

(R)-(-)-Phenylephrine hydrochloride, USP grade

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Pureza: 97.5 - 102.0 %

Cor e Forma: White to off-white powder

Peso molecular: 203.67

Ref: 7W-GL0912

(R)-(-)-Phenylephrine hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Pureza: (Titration) ≥ 99.0% (dried basis)

Cor e Forma: White to off-white powder

Peso molecular: 203.67

Ref: 7W-GL9617

Phenylephrine Hydrochloride

CAS: 61-76-7

Cor e Forma: Neat

Ref: 86-MM0081.00

Phenylephrine Hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂HCl

Peso molecular: 167.21 : 36.46

Ref: ST-EA-CP-P12016

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Stability Hygroscopic
Applications (R)-Phenylephrine Hydrochloride is an α-Adrenergic agonist. Mydriatic; decongestant.
References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946); Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974);

Fórmula: C₉H₁₃NO₂·ClH

Cor e Forma: White To Off-White

Peso molecular: 203.67

Ref: TR-P320640

Phenylephrine hydrochloride

CAS: 61-76-7

(R)-Phenylephrine hydrochloride is a non selective alpha adrenergic agonist that can be used as a bronchodilator or vasopressor. Some research studies in rat liver microsomes has shown that (R)-phenylephrine can be converted to phenylephrine by alcohol dehydrogenase at a rate constant of around 1.8x103 M-1s-1 at 37°C. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle and increase blood pressure by stimulating alpha-adrenergic receptors in the body. This drug is also used in chromatography for control analysis and detection of adulteration with other compounds, such as norepinephrine, with the help of benzalkonium chloride.In ophthalmology, phenylephrine hydrochloride formulations are used for the treatment of eye disorders such as myopia, hypermetropia and astigmatism. It increases the outflow of aqueous humour from the eye by acting on alpha receptors in the ciliary body, and seems to be effective in controlling symptoms of allergic rhinitis and chronic urticaria.

Fórmula: C₉H₁₄NO₂Cl

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 203.67 g/mol

Ref: 3D-FP26956

(R)-Phenylephrine HCl - Bio-X ™

CAS: 61-76-7

(R)-Phenylephrine is a non-selective α1-adrenoceptor agonist that can be used as a bronchodilator or vasopressor. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle cells and increase blood pressure by stimulating alpha-adrenergic receptors in the body. Also, this drug is used to relieve nasal discomfort caused by colds and allergies and is used to relieve sinus congestion and pressure.

Fórmula: C₉H₁₃NO₂•HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 203.67 g/mol

Ref: 3D-BP166231