CAS 61477-96-1

Piperacilina

Descrição:

Piperacilina é um antibiótico penicilínico semissintético que é usado principalmente para tratar uma variedade de infecções bacterianas. É eficaz contra um amplo espectro de bactérias gram-positivas e gram-negativas, incluindo Pseudomonas aeruginosa. Piperacilina atua inibindo a síntese da parede celular bacteriana, levando à lise celular e morte. O composto é tipicamente administrado por injeção, pois não é bem absorvido quando tomado por via oral. Sua estrutura química inclui um anel beta-lactâmico, que é característico das penicilinas, e uma cadeia lateral que aumenta sua atividade contra certas bactérias resistentes. Piperacilina é frequentemente combinado com um inibidor de beta-lactamase, como o tazobactam, para estender sua eficácia contra organismos produtores de beta-lactamase. Os efeitos colaterais comuns podem incluir reações alérgicas, distúrbios gastrointestinais e potenciais impactos na função renal. Devido à sua atividade de amplo espectro, Piperacilina é frequentemente utilizado em ambientes hospitalares para infecções graves, particularmente em pacientes imunocomprometidos.

Fórmula: C₂₃H₂₇N₅O₇S

InChI: InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1

Chave InChI: InChIKey=IVBHGBMCVLDMKU-GXNBUGAJSA-N

SMILES: N(C([C@H](NC(=O)N1C(=O)C(=O)N(CC)CC1)C2=CC=CC=C2)=O)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]

Sinónimos:

• (2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(S*)]]-
• Pipracil
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsaure
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• acide [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazine-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique
• acido [2S-[2α,5α,6β(S*)]]-6-[[[[(4-etil-2,3-dioxopiperazin-1-il)carbonil]amino]fenilacetil]amino]-3,3-dimetil-7-oxo-4-tia-1-azabiciclo[3.2.0]heptano-2-carboxilico
• Piperacillin

Piperacillin Sodium Salt

CAS: 59703-84-3, 61477-96-1

Fórmula: C₂₃H₂₆N₅NaO₇S

Pureza: >98.0%(N)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 539.54

Ref: 3B-P1774

Piperacillin, 95%

CAS: 61477-96-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₃H₂₆N₅NaO₇S

Pureza: 95%

Cor e Forma: White, Powder or crystals or crystalline powder

Peso molecular: 539.54

Ref: 02-J66143

Piperacillin

CAS: 61477-96-1

Cor e Forma: Neat

Ref: 61-FOR0295.00

(2S,5R,6R)-6-[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 517.5548

Ref: IN-DA00IAVJ

Piperacillin

CAS: 61477-96-1

Pureza: ≥ 95.0%

Cor e Forma: White to off-white powder

Peso molecular: 517.56

Ref: 7W-GA9881

Piperacillin-d5 (N-ethyl-d5)

CAS: 61477-96-1

Fórmula: C₂₃H₂₂D₅N₅O₇S

Cor e Forma: White To Off-White Solid

Peso molecular: 522.59

Ref: 4Z-P-7410

Piperacillin

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Cor e Forma: White To Off-White Solid

Peso molecular: 517.56

Ref: 4Z-P-7421

piperacillin

CAS: 61477-96-1

piperacillin

Pureza: ≥98%

Peso molecular: 517.55g/mol

Ref: 54-BUP16669

PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile

CAS: 10206-21-0, 104557-24-6, 113-98-4, 118443-89-3, 132-98-9, 13412-64-1, 1385046-35-4, 23325-78-2, 24356-60-3, 27164-46-1, 50370-12-2, 56238-63-2, 61336-70-7, 61477-96-1, 62893-20-3, 63358-49-6, 68373-14-8, 7081-44-9, 7177-48-2, 7240-38-2, 80370-57-6, 89786-04-9, 985-16-0

Cor e Forma: Mixture

Ref: 04-A30000036WL

Piperacillin

Produto Controlado

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Cor e Forma: Neat

Peso molecular: 517.55

Ref: 86-MM0295.00

Piperacillin

Produto Controlado

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Cor e Forma: Neat

Peso molecular: 517.55

Ref: 04-C16218900

piperacillin

CAS: 61477-96-1

Piperacillin (Pipercillin) is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains)

Fórmula: C₂₃H₂₇N₅O₇S

Pureza: 98.32% - 98.51%

Cor e Forma: Solid

Peso molecular: 517.55

Ref: TM-T8620

Piperacillin-d5 (phenyl-d5)

CAS: 61477-96-1

Fórmula: C₂₃H₂₂D₅N₅O₇S

Peso molecular: 522.59

Ref: 4Z-P-749

Piperacillin

Produto Controlado

CAS: 61477-96-1

Applications Broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial.
References Takai, A., et al.: Chemotherapy, 25, 816 (1977); Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978); Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978);

Fórmula: C₂₃H₂₇N₅O₇S

Cor e Forma: White

Peso molecular: 517.55

Ref: TR-P479950

Piperacillin-d5

Produto Controlado

CAS: 61477-96-1

Fórmula: C₂₃₂H₅H₂₂N₅O₇S

Cor e Forma: Off-White

Peso molecular: 522.59

Ref: TR-P479952

Piperacillin

CAS: 61477-96-1

Piperacillin is a β-lactam antibiotic that inhibits the synthesis of bacterial cell walls by binding to penicillin-binding proteins. It is used for the treatment of serious infections caused by gram-negative organisms such as Aerogenes, Enterobacter, and Klebsiella. Piperacillin has a high MIC90 value against Staphylococcus and other gram-positive bacteria, but it is not active against β-lactamase producing strains of bacteria such as E. coli or Klebsiella pneumoniae. The MIC90 values are determined through an analytical method on different strains of bacteria and validated with a sample preparation before use in clinical trials.

Fórmula: C₂₃H₂₇N₅O₇S

Pureza: Min. 95 Area-%

Cor e Forma: White Powder

Peso molecular: 517.56 g/mol

Ref: 3D-FE27060

Piperacillin-d5

CAS: 61477-96-1

Piperacillin-d5 is a stable isotopically labeled antibiotic, which is synthesized chemically to incorporate deuterium atoms. It is derived from the β-lactam group of antibiotics, sharing properties with its non-labeled counterpart, piperacillin. The incorporation of five deuterium atoms allows researchers to use it as a tracer in various pharmacokinetic and metabolic studies without altering its biological activity.

Fórmula: C₂₃H₂₂D₅N₅O₇S

Pureza: Min. 95%

Peso molecular: 522.59 g/mol

Ref: 3D-AP184289