CAS 6170-42-9

Cloropiramina hidrocloridrato

Descrição:

Cloropiramina hidrocloridrato é um antihistamínico pertencente à classe das fenotiazinas, utilizado principalmente por suas propriedades antialérgicas. É caracterizado por sua capacidade de bloquear os receptores de histamina H1, aliviando assim os sintomas associados a reações alérgicas, como coceira, espirros e nariz escorrendo. O composto aparece como um pó cristalino branco a off-white, que é solúvel em água e apresenta um sabor ligeiramente amargo. Sua estrutura química inclui um anel de pirimidina, contribuindo para sua atividade farmacológica. Cloropiramina hidrocloridrato é frequentemente utilizado no tratamento de condições alérgicas, incluindo febre do feno e urticária, e também pode ter efeitos sedativos devido à sua atividade no sistema nervoso central. Como muitos antihistamínicos, pode causar efeitos colaterais como sonolência, boca seca e tontura. A dosagem e administração adequadas são cruciais para minimizar os efeitos adversos e garantir a eficácia terapêutica. É importante consultar profissionais de saúde para o uso apropriado e estar ciente de possíveis interações com outros medicamentos.

Fórmula: C₁₆H₂₀ClN₃·ClH

InChI: InChI=1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H

Chave InChI: InChIKey=VEYWWAGBHABATA-UHFFFAOYSA-N

SMILES: N(CC1=CC=C(Cl)C=C1)(CCN(C)C)C2=CC=CC=N2.Cl

Sinónimos:

• 1,2-Ethanediamine, N-((4-chlorophenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-, monohydrochloride (9CI)
• 1,2-Ethanediamine, N-[(4-chlorophenyl)methyl]-N′,N′-dimethyl-N-2-pyridinyl-, monohydrochloride
• 1,2-Ethanediamine, N¹-[(4-chlorophenyl)methyl]-N²,N²-dimethyl-N¹-2-pyridinyl-, hydrochloride (1:1)
• 2-[(4-chlorobenzyl)(pyridin-2-yl)amino]-N,N-dimethylethanaminium chloride
• Alergosan
• Allergan S hydrochloride
• Cfak-C 4
• Chloropyramine HCl
• Chloropyribenzamine hydrochloride
• Chlorpiramin hydrochloride
• Chlorpyramine hydrochloride
• G 12144
• Halopyramine hydrochloride
• N-(β-Dimethylaminoethyl)-N-(p-chlorobenzyl)-α-aminopyridine hydrochloride
• Nilfan
• Nsc 409949
• Pyridine, 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-, monohydrochloride (8CI)
• Pyridine, 2-[(p-chlorobenzyl)[2-(dimethylamino)ethyl]amino]-, monohydrochloride
• Sinopen
• Sinopen hydrochloride
• Suprastin
• Suprastin hydrochloride
• Unii-Fwa92Z14Nn
• Chloropyramine hydrochloride

Chloropyramine hydrochloride

CAS: 6170-42-9

Competitive reversible H-1 receptor antagonist

Fórmula: C₁₆H₂₀ClN₃•HCl

Peso molecular: 326.26

Ref: 02-J60350

Chloropyramine Hydrochloride

CAS: 6170-42-9

Cor e Forma: Neat

Ref: 61-FOR1894.00

N1-(4-Chlorobenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride

CAS: 6170-42-9

Fórmula: C₁₆H₂₁Cl₂N₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 326.2640

Ref: IN-DA003OUK

Chloropyramine hydrochloride

CAS: 6170-42-9

Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.

Fórmula: C₁₆H₂₀ClN₃·HCl

Pureza: 99.45% - 99.8%

Cor e Forma: Solid

Peso molecular: 326.26

Ref: TM-T0263

Chloropyramine hydrochloride

CAS: 6170-42-9

Fórmula: C₁₆H₂₀ClN₃·HCl

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 326.26

Ref: 7W-GX9288

Chloropyramine hydrochloride

CAS: 6170-42-9

Chloropyramine hydrochloride

Pureza: ≥98%

Peso molecular: 326.26g/mol

Ref: 54-BUP16269

N1-(4-Chlorobenzyl)-N2,N2-Dimethyl-N1-(Pyridin-2-Yl)Ethane-1,2-Diamine Hydrochloride

CAS: 6170-42-9

N1-(4-Chlorobenzyl)-N2,N2-Dimethyl-N1-(Pyridin-2-Yl)Ethane-1,2-Diamine Hydrochloride

Pureza: 98%

Peso molecular: 326.26g/mol

Ref: 54-OR1026294

Chloropyramine Hydrochloride

CAS: 6170-42-9

Fórmula: C₁₆H₂₀ClN₃·ClH

Cor e Forma: Neat

Peso molecular: 326.26

Ref: 86-MM1894.00

Chloropyramine Hydrochloride

CAS: 6170-42-9

Applications Chloropyramine hydrochloride is a neurotransmitter related agent for research of drug analysis. Also, it is designed to disrupt the focal adhesion kinase (FAK) and vascular endothelial growth factor receptor-3 (VEGFR-3) interaction in neuroblastoma.
References Stewart, J. E., et al.: Mol. Carcinog., 54, 9-23 (2015)

Fórmula: C₁₆H₂₀ClN₃·ClH

Cor e Forma: Neat

Peso molecular: 326.26

Ref: TR-C381268

Chloropyramine HCl

CAS: 6170-42-9

Chloropyramine is a drug that has been used to treat autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. It is an antihistamine drug that acts by blocking the histamine receptor. Chloropyramine has been shown to have an effect on diastolic pressure in animal models. The model system used was human serum with locomotor activity as the endpoint. The sample preparation involved calcium pantothenate, which is a precursor of coenzymes A and C. The pharmacological agent chloropyramine binds to the agonist binding site, which is located at the end of the cell membrane and regulates ion channels, including those for calcium ions. Tricyclic antidepressant drugs are known to bind to this same binding site, inhibiting the action of both histamine and chloropyramine. Histamine causes increased blood flow due to vasodilation by stimulating H1 receptors in smooth muscles cells. Histamine

Fórmula: C₁₆H₂₀ClN₃·HCl

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 326.26 g/mol

Ref: 3D-FC149051

N1-(4-Chlorobenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride

CAS: 6170-42-9

Fórmula: C₁₆H₂₁Cl₂N₃

Pureza: ≥98%

Peso molecular: 326.27

Ref: 10-F324024

Chloropyramine Hydrochloride

CAS: 6170-42-9

Fórmula: C₁₆H₂₀ClN₃HCl

Peso molecular: 289.8 : 36.5

Ref: ST-EA-CP-C341008