CAS 6190-39-2
:Mesilato de diidroergotamina
Descrição:
Mesilato de diidroergotamina é um derivado semissintético de alcaloides do ergot, utilizado principalmente no tratamento de enxaquecas e cefaleias em cluster. Atua como um vasoconstritor, direcionando-se aos receptores de serotonina para aliviar os sintomas de dor de cabeça. A substância é tipicamente administrada por vias intranasais ou intravenosas, permitindo um início rápido de ação. Mesilato de diidroergotamina é caracterizado por sua relativamente baixa solubilidade em água, o que pode afetar sua formulação e métodos de entrega. A forma de sal mesilato melhora sua estabilidade e biodisponibilidade. Efeitos colaterais comuns podem incluir náuseas, tontura e potenciais efeitos cardiovasculares devido às suas propriedades vasoconstritoras. É contraindicado em pacientes com certas condições cardiovasculares e deve ser usado com cautela em aqueles com histórico de hipertensão. Como com todos os medicamentos, é essencial seguir as diretrizes de dosagem e monitorar reações adversas. No geral, Mesilato de diidroergotamina é um agente terapêutico valioso no manejo de ataques agudos de enxaqueca, oferecendo alívio para muitos pacientes quando usado adequadamente.
Fórmula:C33H37N5O5·CH4O3S
InChI:InChI=1S/C33H37N5O5.CH4O3S/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;1-5(2,3)4/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39);1H3,(H,2,3,4)/t21-,23-,25-,26+,27+,32-,33+;/m1./s1
Chave InChI:InChIKey=ADYPXRFPBQGGAH-UMYZUSPBSA-N
SMILES:O[C@@]12N([C@@H](CC3=CC=CC=C3)C(=O)N4[C@]1(CCC4)[H])C(=O)[C@@](NC(=O)[C@@H]5C[C@@]6(C=7C=8C(C[C@]6(N(C)C5)[H])=CNC8C=CC7)[H])(C)O2.S(C)(=O)(=O)O
Sinónimos:- (2'Ξ,5'Α,12'Ξ)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (Salt)
- (5'Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (Salt)
- (5'Alpha,10Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (1:1)
- 9,10-Dihydroergotamine mesylate
- Agit
- Angionorm
- Dergotamine
- Detms
- Dhe 45
- Diergo
- Dihydergot
- Dihydroergotamine Mesilate
- Dihydroergotamine Methanesulfonate
- Dihydroergotamine methanesulphonate
- Dihydroergotamine monomethanesulfonate
- Dihydroergotaminmesilat
- Dihytamine
- Dirgotarl
- Endophleban
- Ergomimet
- Ergont
- Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-, methanesulfonate (1:1)
- Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-, monomethanesulfonate (salt)
- Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α,10α)-, methanesulfonate (1:1)
- Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α,10α)-, monomethanesulfonate (salt)
- Ergotamine, 9,10-dihydro-, monomethanesulfonate (salt)
- Ergotonin
- Ikaran
- Mesilate De Dihydroergotamine
- Mesilato De Dihidroergotamina
- Migranal
- Morena
- Orstanorm
- Seglor
- Tonopres
- Verladyn
- (2'ξ,5'α,12'ξ)-5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman methanesulfonate (salt)
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13 produtos.
Dihydroergotamine methanesulfonate
CAS:<p>Agonist at vascular serotonin receptors; partial agonist at alpha-adrenergic and dopamine D2 receptors This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aes</p>Fórmula:C34H41N5O8SCor e Forma:Powder or crystals or crystalline powder, White to pale yellow to pale redPeso molecular:679.79DIHYDROERGOTAMINE FOR PEAK IDENTIFICATION CRS
CAS:DIHYDROERGOTAMINE FOR PEAK IDENTIFICATION CRSFórmula:C34H41N5O8SPeso molecular:679.783DIHYDROERGOTAMINE MESILATE CRS
CAS:DIHYDROERGOTAMINE MESILATE CRSFórmula:C34H41N5O8SCor e Forma:Crystalline Powder. White. Colourless Crystals. Powder.Peso molecular:679.783Dihydroergotamine Mesylate
CAS:Alkaloids of rye ergot and their derivatives; salts thereof, nesoiFórmula:C33H37N5O5·CH4O3SCor e Forma:White Off-White PowderPeso molecular:679.26758Dihydroergotamine methanesulfonate salt
CAS:Fórmula:C33H37N5O5·CH4O3SCor e Forma:White to pale-yellow or pale-red powder or crystalsPeso molecular:679.78Dihydroergotamine Mesylate
CAS:Fórmula:C33H37N5O5·CH4O3SPureza:>97.0%(HPLC)Cor e Forma:White to Light yellow to Light red powder to crystalPeso molecular:679.79Dihydroergotamine Mesylate
CAS:Produto Controlado<p>Applications α-Androgenic blocker with selective venoconstrictor properties. Also binds to serotonin 5HT1-receptors. Antimigraine.<br>References de Marees, et al.: Eur. J. Clin. Pharmacol., 30, 685 (1986), McCarthy, B.G., et al.: Headache, 29, 420 (1989), Ziegler, D., et al.: Neurology, 44, 447 (1994),<br></p>Fórmula:C33H37N5O5·CH4O3SCor e Forma:White To Off-WhitePeso molecular:679.78Dihydro ergotamine mesylate
CAS:Produto Controlado<p>Dihydroergotamine mesylate is a medication that is used in the treatment of migraines. It belongs to the group of drugs called ergot alkaloids and has been shown to have high values in cerebral metabolism. Dihydroergotamine mesylate has also been shown to have an effect on dopamine levels in human serum, which may be due to its ability to inhibit neuronal death. Dihydroergotamine mesylate is administered intravenously, orally or intramuscularly for the treatment of acute migraine attacks. The drug can also be given rectally for the prevention of chronic migraine episodes. This drug may cause side effects such as nausea, vomiting and dizziness.</p>Fórmula:C34H41N5O8SPureza:Min. 95%Cor e Forma:PowderPeso molecular:679.78 g/molDihydroergotamine mesylate
CAS:Produto ControladoFórmula:C33H37N5O5·CH4O3SCor e Forma:NeatPeso molecular:679.78
