CAS 6230-11-1

O-Metil-L-tirosina

Descrição:

O-Metil-L-tirosina, também conhecido como 3-metoxi-L-tirosina, é um derivado de aminoácido caracterizado pela presença de um grupo metóxi (-OCH3) ligado ao anel aromático da estrutura da tirosina. Essa modificação melhora sua solubilidade e altera suas propriedades bioquímicas em comparação com a L-tirosina padrão. O composto é frequentemente utilizado em pesquisas bioquímicas e estudos relacionados à síntese de neurotransmissores, pois pode influenciar a produção de catecolaminas. Sabe-se que O-Metil-L-tirosina atua como um inibidor competitivo da tirosina hidroxilase, a enzima responsável por converter L-tirosina em L-DOPA, afetando assim a síntese de dopamina. Geralmente é encontrado em forma cristalina e é solúvel em solventes polares. A substância tem aplicações potenciais em farmacologia e neurobiologia, particularmente na compreensão do papel dos neurotransmissores em vários processos fisiológicos. Assim como muitos derivados de aminoácidos, sua segurança e eficácia em contextos terapêuticos requerem uma avaliação cuidadosa por meio de estudos clínicos.

Fórmula: C₁₀H₁₃NO₃

InChI: InChI=1/C10H13NO3/c1-14-8-4-2-7(3-5-8)6-9(11)10(12)13/h2-5,9H,6,11H2,1H3,(H,12,13)

Chave InChI: InChIKey=GEYBMYRBIABFTA-VIFPVBQESA-N

SMILES: C([C@@H](C(O)=O)N)C1=CC=C(OC)C=C1

Sinónimos:

• (2S)-2-Amino-3-(4-methoxyphenyl)propanoic acid
• (S)-2-Amino-3-(4-methoxyphenyl)propanoic acid
• 4-Methoxy-L-phenylalanine
• <span class="text-smallcaps">L</span>-4-Methoxyphenylalanine
• <span class="text-smallcaps">L</span>-O-Methyltyrosine
• <span class="text-smallcaps">L</span>-Tyrosine methyl ether
• <span class="text-smallcaps">L</span>-Tyrosine, O-methyl-
• Alanine, 3-(p-methoxyphenyl)-, <span class="text-smallcaps">L</span>-
• H-Tyr(Me)-OH
• L-4-Methoxyphenylalanine
• NSC 30082
• O-Methyl-<span class="text-smallcaps">L</span>-tyrosine
• O-methyltyrosine
• p-Methoxy-<span class="text-smallcaps">L</span>-phenylalanine
• p-Methoxy-L-phenylalanine
• β-(4-Methoxyphenyl)-<span class="text-smallcaps">L</span>-alanine
• O-Methyl-L-tyrosine
• Alanine, 3-(p-methoxyphenyl)-, L-
• L-Tyrosine, O-methyl-
• (2S)-2-Amino-3-(4-methoxyphenyl)propionic acid
• (S)-2-AMINO-3-(4-METHOXY-PHENYL)-PROPIONIC ACID
• 4-METHOXY-PHE-OH
• L-4-METHOXYPHE
• 4-METHOXYPHENYLALANINE
• H-L-Tyr(Me)-OH
• (S)-α-Amino-4-methoxybenzenepropanoic acid
• H-4-METHOXY-PHE-OH
• L-4-MeO-Phe-OH
• TYROSINE(ME)-OH
• L-H-Tyr(Me)-OH
• H-P-METHOXY-PHE-OH
• P-METHOXYPHENYLALANINE
• (2R)-2-amino-3-(4-methoxyphenyl)propanoic acid
• L-TYROSINE-O-METHYL ETHER

O-Methyl-L-tyrosine

CAS: 6230-11-1

Fórmula: C₁₀H₁₃NO₃

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 195.22

Ref: 3B-M2276

O-Methyl-L-tyrosine, 98%

CAS: 6230-11-1

O-Methyl-L-tyrosine, is used as a fine chemical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference h

Fórmula: C₁₀H₁₃NO₃

Pureza: 98%

Peso molecular: 195.22

Ref: 02-H63096

H-Tyr(Me)-OH

CAS: 6230-11-1

Bachem ID: 4003985.

Fórmula: C₁₀H₁₃NO₃

Pureza: > 99%

Cor e Forma: White Powder

Peso molecular: 195.22

Ref: 01-4003985

H-Tyr(Me)-OH

CAS: 6230-11-1

Fórmula: C₁₀H₁₃NO₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 195.2151

Ref: IN-DA003LNW

4-Methoxy-L-phenylalanine

CAS: 6230-11-1

4-Methoxy-L-phenylalanine

Pureza: 98%

Peso molecular: 195.22g/mol

Ref: 54-OR927182

O-Methyl-L-tyrosine

CAS: 6230-11-1

Peso molecular: 195.22

Ref: 7W-GM3349

O-Methyl-L-tyrosine

CAS: 6230-11-1

O-Methyl-L-tyrosine is a non-protein amino acid that inhibits protein synthesis by preventing the formation of peptide bonds. It has been shown to be an effective inhibitor of methionyl and cysteyl synthetases, which are enzymes that synthesize proteins. O-Methyl-L-tyrosine has also been used in clinical studies to treat translation defects associated with Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA). This drug is a synthetic amino acid that is not found in nature. Its structure consists of two methyl groups bonded to the oxygen atom on the tyrosine side chain, making it more stable than L-tyrosine. OMT binds to the enzyme methionyl synthetase in its active site, preventing formation of peptide bonds during protein synthesis. In addition, this drug has been shown to inhibit methyltetrahydrofolate reductase, an enzyme involved

Fórmula: C₁₀H₁₃NO₃

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 195.22 g/mol

Ref: 3D-FM25869

4-Methoxy-phenylalanine

CAS: 6230-11-1

M03187 - 4-Methoxy-phenylalanine

Fórmula: C₁₀H₁₃NO₃

Pureza: 98%

Cor e Forma: Solid, White powder

Peso molecular: 195.218

Ref: 10-M03187

O-Methyl-L-tyrosine

Produto Controlado

CAS: 6230-11-1

Applications A non-natural Phenylalanine (P319415) derivative.
References Paradisi, F., et al.: J. Biotechnol., 128, 408 (2007),

Fórmula: C₁₀H₁₃NO₃

Cor e Forma: Neat

Peso molecular: 195.22

Ref: TR-M332675