CAS 6244-92-4

Lauroil-CoA

Descrição:

Lauroil-CoA, também conhecido como coenzima A lauroil, é um derivado de acil-CoA que desempenha um papel crucial no metabolismo e biossíntese de lipídios. É caracterizado por um ácido graxo de cadeia longa, especificamente o ácido láurico, que consiste em 12 átomos de carbono. A estrutura de Lauroil-CoA inclui um grupo de coenzima A que facilita sua participação em várias reações bioquímicas, particularmente na síntese e degradação de ácidos graxos. Este composto é tipicamente encontrado em compartimentos celulares, como as mitocôndrias e o citoplasma, onde participa de vias metabólicas, incluindo a oxidação de ácidos graxos e a síntese de lipídios complexos. Lauroil-CoA também é importante na formação de lipídios de membrana e moléculas de sinalização. Sua atividade é regulada por várias enzimas, incluindo acil-CoA sintetasas e aciltransferases, que modulam sua disponibilidade e função em processos metabólicos. No geral, Lauroil-CoA é essencial para manter o equilíbrio energético celular e a homeostase lipídica.

Fórmula: C₃₃H₅₈N₇O₁₇P₃S

InChI: InChI=1S/C33H58N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40/h20-22,26-28,32,43-44H,4-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48)/t22-,26-,27-,28+,32-/m1/s1

Chave InChI: InChIKey=YMCXGHLSVALICC-GMHMEAMDSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCSC(CCCCCCCCCCC)=O)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Sinónimos:

• Coenzyme A, S-dodecanoate
• Coenzyme A, S-laurate
• Coenzyme A, lauroyl-
• Dodecanethioic acid, S-ester with coenzyme A
• Dodecanoyl-coa
• Dodecanoyl-coenzyme A
• Lauroyl-coa
• Lauroyl-coenzyme A
• Lauryl coenzyme A
• Lauryl-CoA
• S-{(9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} dodecanethioate (non-preferred name)

Lauroyl-coenzyme A

CAS: 6244-92-4

Lauroyl-coenzyme A acts as an acyl carrier, involved in lipid metabolism, biosynthesis, and fatty acid transport.

Fórmula: C₃₃H₅₈N₇O₁₇P₃S

Cor e Forma: Solid

Peso molecular: 949.84

Ref: TM-T32598

Dodecanoyl Coenzyme A K salt

CAS: 6244-92-4

Fórmula: C33H58N7O17P3S

Pureza: >95%

Cor e Forma: Solid

Peso molecular: 949.84

Ref: 48-19-1200

Lauroyl Coenzyme A, Free acid

CAS: 6244-92-4

Pureza: 95%

Peso molecular: 949.282

Ref: 10-C300039

Lauroyl coenzyme A

CAS: 6244-92-4

Lauroyl CoA is a body-fat molecule that can be formed from acetyl-coenzyme A, which is an intermediate in the metabolism of fatty acids. It is used in analysis as a standard for enzyme activities and as a substrate for reactions involving enzymes with coenzyme A. Reaction mechanisms are determined using titration calorimetry and structural analyses are performed using analytical methods such as infrared spectroscopy and nuclear magnetic resonance spectroscopy. Lauroyl CoA is also used to study the effects of the protein toll-like receptor 4 on hepatic steatosis. The wild-type strain of Escherichia coli was used to measure the activity of bacterial synthetases containing lauroyl CoA.

Fórmula: C₃₃H₅₈N₇O₁₇P₃S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 949.84 g/mol

Ref: 3D-NL47197

Lauroyl coenzyme A potassium salt

CAS: 6244-92-4

Lauroyl coenzyme A potassium salt is a potent inhibitor of fatty acid synthase. It has the ability to inhibit the enzyme activity of fatty acid synthase in vitro, which belongs to the class of irreversible inhibitors. Lauroyl coenzyme A potassium salt inhibits the synthesis of fatty acids by inhibiting the enzyme activity of fatty acid synthase. This inhibitor also reversibly inhibits other enzymes with a similar mechanism, such as acetyl-coenzyme A carboxylase and phosphatidate phosphohydrolase. The reaction mechanism can be understood through titration calorimetry studies, demonstrating that lauroyl coenzyme A potassium salt binds to the active site of these enzymes and blocks access to substrates. The binding affinity is higher for wild type strains than for mutant strains, which may be due to differences in protein structure or other factors. Lauroyl coenzyme A potassium salt has been shown to have no effect on wild-type strains but inhibits polymer

Fórmula: C₃₃H₅₅N₇O₁₇P₃SK₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 1,064.11 g/mol

Ref: 3D-NL161093