CAS 63-89-8

1,2-Dipalmitoil-sn-glicero-3-fosfocolina

Descrição:

1,2-Dipalmitoil-sn-glicero-3-fosfocolina (DPPC) é um fosfolípido comumente utilizado em bioquímica e biofísica, particularmente em estudos envolvendo membranas celulares e lipossomos. É caracterizado por suas duas cadeias de ácido palmítico, que são ácidos graxos saturados, contribuindo para sua estabilidade estrutural e rigidez em temperaturas fisiológicas. O DPPC possui uma estrutura de glicerol com um grupo fosfato ligado ao terceiro carbono, que está ainda ligado a um grupo colina, tornando-se uma molécula zwitteriônica. Essa estrutura única permite que o DPPC forme bicamadas em ambientes aquosos, imitando membranas biológicas. Ele exibe uma temperatura de transição de fase, abaixo da qual está em um estado gel e acima da qual transita para um estado fluido, influenciando a fluidez e permeabilidade da membrana. O DPPC também é utilizado em sistemas de entrega de medicamentos e como surfactante em várias formulações farmacêuticas devido à sua capacidade de estabilizar emulsões e aumentar a solubilidade de compostos hidrofóbicos. Seu número CAS é 63-89-8, indicando sua identificação única em bancos de dados químicos.

Fórmula: C₄₀H₈₀NO₈P

InChI: InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1

Chave InChI: InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N

SMILES: [C@H](OC(CCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O

Sinónimos:

• (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid
• (R)-(4-oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide
• (R)-2,3-Bis(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
• 1,2-<span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidylcholine
• 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine
• 1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phophocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine
• 1,2-Dihexadecanoyl-sn-glycerol-3-phosphorylcholine
• 1,2-Dipalmitoyl-3-Sn-Phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-3-phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-lecithin
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-lecithin
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• 1,2-Dipalmitoyl-L-3-phosphatidylcholine
• 1,2-Dipalmitoyl-L-lecithin
• 1,2-Dipalmitoyl-L-phosphatidylcholine
• 1,2-Dipalmitoyl-L-α-lecithin
• 1,2-Dipalmitoyl-L-α-phosphatidylcholine
• 1,2-Dipalmitoyl-sn-3-glycerophosphocholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine monohydrate
• 1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine
• 1,2-Dipalmitoyl-sn-glycerol-3-phosphocholine
• 1,2-Dipalmitoyl-sn-glycerophosphocholine
• 1,2-Dipalmitoyl-sn-glycerophosphorylcholine
• 1,2-Dipalmitoyl-sn-glyceryl-3-phosphocholine
• 1,2-Dipalmitoyl-sn-phosphatidylcholine
• 1,2-Dipalmitoylglycero-3-phosphocholine
• 1,2-Dispalmitoyl-sn-phosphatidylcholine
• 1,2-L-α-Dipalmitoylphosphatidylcholine
• 1,2-Palmitoyl-sn-glycero-3-phosphocholine
• 1,2-dipalmitoyl-L-alpha-phosphatidylcholine
• 129Y83
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, hydroxide, inner salt, 4-oxide, (R)-
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (R)-
• 4-oxido de (R)-(4-oxido-10-oxo-7-palmitoil-3,5,9-trioxa-4-fosfapentacosil)trimetilamonio
• 4-oxyde de (R)-(4-oxydo-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium
• 55: PN: WO2017201317 SEQID: 128 claimed RNA
• <span class="text-smallcaps">L</span>-1,2-Dipalmitoyl-α-lecithin
• <span class="text-smallcaps">L</span>-1,2-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-DPPC
• <span class="text-smallcaps">L</span>-Dipalmitoyl lecithin
• <span class="text-smallcaps">L</span>-Dipalmitoyl phosphatidylcholine
• <span class="text-smallcaps">L</span>-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-1,2-Dipalmitoyl lecithin
• <span class="text-smallcaps">L</span>-α-DPPC
• <span class="text-smallcaps">L</span>-α-Dipalmitoylecithin
• <span class="text-smallcaps">L</span>-α-Dipalmitoyllecithin
• <span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-Lecithin
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoyl-α-lecithin
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoyl-α-phosphatidylcholine
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoylphosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipalmitin, <span class="text-smallcaps">L</span>-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipalmitin, L-
• Colfosceril Palmitate
• Dihexadecanoyl-sn-glycero-3-phosphocholine
• Dipalmitoyl L-α-phosphatidylcholine
• Dipalmitoyl-<span class="text-smallcaps">L</span>-3-glycerylphosphorylcholine
• Dipalmitoyl-<span class="text-smallcaps">L</span>-lecithin
• Dipalmitoyl-<span class="text-smallcaps">L</span>-α-lecithin
• Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• Dipalmitoyl-L-3-glycerylphosphorylcholine
• Dipalmitoyl-L-α-lecithin
• Dipalmitoyl-sn-3-phosphatidylcholine
• Dipalmitoyl-sn-glycero-3-phosphocholine
• Dipalmitoylphosphatidylcholine
• Dppc
• L-1,2-Dipalmitoyl-α-lecithin
• L-1,2-Dipalmitoylphosphatidylcholine
• L-A-phosphatidylcholine dipalmitoyl*synthetic
• L-Dipalmitoyl lecithin
• L-Dppc
• L-a-Dipalmitoyl Lecithin
• L-a-Lecitin-dipalmitoyl
• L-α-1,2-Dipalmitoyl lecithin
• L-α-DPPC
• L-α-Dipalmitoylecithin
• L-α-Dipalmitoyllecithin
• L-α-Dipalmitoylphosphatidylcholine
• L-α-Lecithin
• L-β,γ-Dipalmitoyl-α-lecithin
• L-β,γ-Dipalmitoyl-α-phosphatidylcholine
• L-β,γ-Dipalmitoylphosphatidylcholine
• Palmitin, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">L</span>-
• [(2R)-2,3-Di(hexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• sn-3-Dipalmitoyllecithin
• β,γ-Dipalmitoyl <span class="text-smallcaps">L</span>-α-phosphatidylcholine
• β,γ-Dipalmitoyl L-α-phosphatidylcholine
• β,γ-Dipalmitoyl-<span class="text-smallcaps">L</span>-(α)-lecithin
• β,γ-Dipalmitoyl-<span class="text-smallcaps">L</span>-phosphatidylcholine
• β,γ-Dipalmitoyl-L-(α)-lecithin
• β,γ-Dipalmitoyl-L-phosphatidylcholine

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Fórmula: C₄₀H₈₀NO₈P

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 734.05

Ref: 3B-D3925

DPPC

CAS: 63-89-8

Pureza: 97%

Peso molecular: 734.052978515625

Ref: 10-F601359

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

DPPC

Fórmula: C₄₀H₈₀NO₈P

Pureza: > 99%

Cor e Forma: White Powder

Peso molecular: 734.05

Ref: 01-4004249

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

Fórmula: C₄₀H₈₀NO₈P

Pureza: By hplc: 98% (Typical Value in Batch COA)

Cor e Forma: white solid

Peso molecular: 734.04g/mol

Ref: 54-BIB6043

DPPC

CAS: 63-89-8

DPPC

Pureza: ≥98%

Peso molecular: 734.04g/mol

Ref: 54-BUP15935

DPPC (Dipalmitoylphosphatidylcholine)

CAS: 63-89-8

Fórmula: C₄₀H₈₀NO₈P

Cor e Forma: White To Off-White Solid

Peso molecular: 734.05

Ref: 4Z-C-594

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Fórmula: C₄₀H₈₀NO₈P

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 734.04

Ref: 7W-GL3400

1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 63-89-8

Fórmula: C40H80NO8P

Pureza: >99%

Cor e Forma: Solid

Peso molecular: 734.04

Ref: 48-37-1600

Succinyl Monocholine-d4 Chloride

CAS: 63-89-8

Fórmula: C₉H₁₄D₄ClNO₄

Cor e Forma: White To Off-White Solid

Peso molecular: 243.72

Ref: 4Z-C-5947

DPPC

CAS: 63-89-8

DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.

Fórmula: C₄₀H₈₀NO₈P

Pureza: 99.33% - 99.5%

Cor e Forma: Solid

Peso molecular: 734.04

Ref: TM-T7773

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (Colfosceril Palmitate)

Produto Controlado

CAS: 63-89-8

Stability Hygroscopic
Applications Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),

Fórmula: C₄₀H₈₀NO₈P

Cor e Forma: Neat

Peso molecular: 734.04

Ref: TR-C640500

Colfosceril-d9 Palmitate

Produto Controlado

CAS: 63-89-8

Applications Labelled Colfosceril Palmitate (C640500). Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),

Fórmula: C₄₀D₉H₇₁NO₈P

Cor e Forma: Neat

Peso molecular: 743.094

Ref: TR-C640502

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) is a sodium salt that has the ability to form surfactant bilayers. DPPC is a model system for studying biochemical reactions and the phase transition of lipid bilayers. This compound has been used to study the effects of various drugs on cell membranes in biochemical research. In addition, DPPC has been shown to have hypoglycemic effects in animal models as well as having an anti-inflammatory effect.

Fórmula: C₄₀H₈₀NO₈P

Pureza: Min. 95 Area-%

Cor e Forma: Powder

Peso molecular: 734.04 g/mol

Ref: 3D-FD46765