CAS 63-92-3

Cloridrato de fenoxibenzamina

Descrição:

Cloridrato de fenoxibenzamina é um antagonista alfa-adrenérgico não seletivo usado principalmente no tratamento de condições como o feocromocitoma, um tipo de tumor que pode causar liberação excessiva de catecolaminas. É caracterizado por sua capacidade de se ligar irreversivelmente aos receptores alfa-adrenérgicos, levando a uma vasodilatação prolongada e à diminuição da pressão arterial. O composto é tipicamente administrado por via oral e é conhecido por sua duração de ação relativamente longa devido ao seu mecanismo de ligação irreversível. Cloridrato de fenoxibenzamina é um pó cristalino branco a quase branco, solúvel em água e álcool, e possui um intervalo de pH que é geralmente neutro. Seus efeitos farmacológicos podem incluir efeitos colaterais como hipotensão ortostática, taquicardia e congestão nasal. Devido ao seu mecanismo de ação, é importante monitorar os pacientes de perto para respostas cardiovasculares. Assim como qualquer medicamento, deve ser usado sob a orientação de um profissional de saúde, considerando possíveis interações e contraindicações.

Fórmula: C₁₈H₂₂ClNO·ClH

InChI: InChI=1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H

Chave InChI: InChIKey=VBCPVIWPDJVHAN-UHFFFAOYSA-N

SMILES: C(N(C(COC1=CC=CC=C1)C)CCCl)C2=CC=CC=C2.Cl

Sinónimos:

• 2-(N-benzyl-2-chloroethylamino)-1-phenoxypropane hydrochloride
• Bensylyt Nen
• Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
• Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (1:1)
• Benzyl(2-Chloroethyl)(1-Methyl-2-Phenoxyethyl)Amine Hydrochloride
• Benzylamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
• Dibenzylin
• Dibenzyline chloride
• Dibenzyline hydrochloride
• Dibenzyran
• Fenoxybenzamin
• N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzenemethanamine hydrochloride
• N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride
• N-2-Phenoxyisopropyl-N-benzyl-β-chloroethylamine hydrochloride
• N-2-phenoxyisopropyl-N-benzyl-chloroethylamine hydrochloride
• N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium
• N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium chloride
• N-phenoxyisopropyl-N-benzyl-beta-chloroethylamine hydrochloride
• NSC 37448
• Phenoxybenzamide Hydrochloride
• Phenoxybenzamide, HCl
• Phenoxybenzamine HCL

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Fórmula: C₁₈H₂₂ClNO·HCl

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 340.29

Ref: 3B-D0158

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Selective alpha adrenergic blocking agent. Irreversible calmodulin inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or

Fórmula: C₁₈H₂₃Cl₂NO

Cor e Forma: White to off-white, Powder

Peso molecular: 340.29

Ref: 02-J61900

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Cor e Forma: Neat

Ref: 61-FOR0778.00

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride

Fórmula: C₁₈H₂₂CINOHCl

Pureza: 97.0%

Cor e Forma: White

Peso molecular: 443.05129

Ref: 47-1072

PHENOXYBENZAMINE HYDROCHLORIDE CRS

CAS: 63-92-3

PHENOXYBENZAMINE HYDROCHLORIDE CRS

Ref: 41-Y0002282

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Aromatic drugs of amino-alcohols, other than those contg > one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Fórmula: C₁₈H₂₂ClNO·HCI

Cor e Forma: White Off-White Powder

Peso molecular: 443.05129

Ref: 45-1526007

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride: non-selective, irreversible alpha-blocker; antihypertensive, vasodilator, may cause tachycardia, potential carcinogen.

Fórmula: C₁₈H₂₃Cl₂NO

Pureza: 98.04% - >99.99%

Cor e Forma: Antihypertensive Drug

Peso molecular: 340.3

Ref: TM-T1158

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Fórmula: C₁₈H₂₂ClNO·HCl

Peso molecular: 340.29

Ref: 7W-GL1636

Phenoxybenzamine HCl

CAS: 63-92-3

Fórmula: C₁₈H₂₂ClNO·HCl

Peso molecular: 303.83 36.46

Ref: 4Z-P-0812

Phenoxybenzamine HCl

CAS: 63-92-3

Phenoxybenzamine HCl

Pureza: 98%

Peso molecular: 340.30g/mol

Ref: 54-OR1014632

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride

Pureza: ≥98%

Peso molecular: 340.3g/mol

Ref: 54-BUP18326

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Fórmula: C₁₈H₂₂ClNO·ClH

Cor e Forma: Neat

Peso molecular: 340.29

Ref: 86-MM0778.00

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride is a drug with pharmacological properties, which is used in the treatment of carcinoid syndrome. It is a combination therapy group that can be used to treat patients with neurological disorders. Phenoxybenzamine inhibits the activity of the 5-HT2 receptors and has been shown to reduce neuronal death. In addition, it has been shown to increase chemiluminescence in cells infected with HIV. Phenoxybenzamine also has effects on cardiac function and can be used to treat congestive heart failure as well as high levels of natriuretic peptides in maternal blood during pregnancy. It has also been shown to be effective against infectious diseases, such as tuberculosis and malaria.

Fórmula: C₁₈H₂₃Cl₂NO

Pureza: Min. 90 Area-%

Cor e Forma: Powder

Peso molecular: 340.29 g/mol

Ref: 3D-FP26891

Phenoxybenzamine.HCl

CAS: 63-92-3

M02323 - Phenoxybenzamine.HCl

Fórmula: C₁₈H₂₃Cl₂NO

Pureza: 98%+(HPLC);RG

Cor e Forma: Solid

Peso molecular: 340.29

Ref: 10-M02323

Phenoxybenzamine Hydrochloride

Produto Controlado

CAS: 63-92-3

Applications An irreversible α-antagonist. Used in the treatment of hypertension, it has a relatively slow onset and prolonged effect when compared to alternative α-blockers.
References Glass, B., et al.: J. Pharm. Pharm. Sci., 9, 398 (2006), Huang, R., et al.: Chem. Res. Toxicol., 21, 659 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Fórmula: C₁₈H₂₂ClNO·ClH

Cor e Forma: Neat

Peso molecular: 340.29

Ref: TR-P227990