CAS 635681-64-0

DNA ligase-IN-2

CAS: 635681-64-0

DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.

Fórmula: C₁₃H₈FN₃O₃

Cor e Forma: Solid

Peso molecular: 273.219

Ref: TM-T204415