CAS 64-72-2

Clortetraciclina hidrocloridrato

Descrição:

Clortetraciclina hidrocloridrato é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, utilizado principalmente na medicina veterinária e em algumas aplicações humanas. É caracterizado por sua aparência cristalina amarela e é solúvel em água, o que facilita seu uso em várias formulações. O composto exibe propriedades antibacterianas ao inibir a síntese de proteínas nas bactérias, tornando-o eficaz contra uma ampla gama de organismos Gram-positivos e Gram-negativos. Clortetraciclina hidrocloridrato é frequentemente utilizado no tratamento de infecções, bem como em ambientes agrícolas para promover o crescimento do gado. Seu mecanismo de ação envolve a ligação à subunidade ribossomal 30S, impedindo a ligação do aminoacil-tRNA, interrompendo assim o processo de tradução. Embora geralmente bem tolerado, pode causar efeitos colaterais como distúrbios gastrointestinais e fotossensibilidade. Além disso, o uso de tetraciclinas levantou preocupações sobre a resistência a antibióticos, exigindo uma consideração cuidadosa de sua aplicação tanto na medicina humana quanto veterinária.

Fórmula: C₂₂H₂₃ClN₂O₈·ClH

InChI: InChI=1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7-,8-,15-,21-,22-;/m0./s1

Chave InChI: InChIKey=CBHYYLPALVVVEY-MRFRVZCGSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)(C[C@]3(C(=C2O)C(=O)C=4C([C@@]3(C)O)=C(Cl)C=CC4O)[H])[H].Cl

Sinónimos:

• (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
• 7-Chlorotetracycline hydrochloride
• 7-Chlorotetracycline monohydrochloride
• Aureociclina
• Aureocycline
• Aureomycin monohydrochloride
• Aureovit 12C80
• Aurofac 100
• Biomycin hydrochloride
• Chlortetracycline hydrochloride
• Chlortetracyclinium chloride
• Fermycin Soluble
• Isphamycin

Chlortetracycline Hydrochloride

Produto Controlado

CAS: 64-72-2

Applications Chlortetracycline is an antibiotic substance isolated from the substrate of Streptomyces aureofaciens. Chlortetracycline is an antimicrobial and antibacterial.Chlortetracycline contains an undetermined amount of epi-chlortetracycline.
References Skaletzki, B., et al.: Pharmazie, 29, 424 (1974), Martinez, M., et al.: Biochemistry, 40, 11965 (2001), Davidson, P., et al.: Food Technol., 55, 69 (2002), de la Fuente, R., et al.: Br. J. Pharmacol., 149, 551 (2006),

Fórmula: C₂₂H₂₃ClN₂O₈·ClH

Cor e Forma: Neat

Peso molecular: 515.34

Ref: TR-C426500

Chlortetracycline-13C-d3 Hydrochloride (Technical Grade, may contain up to 1.5% d0)

Produto Controlado

CAS: 64-72-2

Fórmula: C₂₁CH₂₀D₃ClN₂O₈·HCl

Cor e Forma: Neat

Peso molecular: 534.386

Ref: TR-C426510

Chlorotetracycline monohydrochloride, Antibiotic for Culture Media Use Only

CAS: 64-72-2

Chlorotetracycline monohydrochloride is an antibiotic compound specifically designed for culture media use. It is derived from a naturally occurring tetracycline produced by the bacterium *Streptomyces aureofaciens*. As a broad-spectrum antibiotic, chlorotetracycline functions by inhibiting protein synthesis in susceptible bacteria. It binds to the 30S subunit of the bacterial ribosome, blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor site, which effectively halts translational elongation.

Fórmula: C₂₂H₂₄Cl₂N₂O₈

Pureza: (Chlortetracycline Hcl) Min. 89.5%

Cor e Forma: Yellow Powder

Peso molecular: 515.34 g/mol

Ref: 3D-AC162429

Chlortetracycline hydrochloride

CAS: 64-72-2

Chlortetracycline hydrochloride is a broad-spectrum antibiotic, which is derived from the bacterium *Streptomyces aureofaciens*. It operates by inhibiting protein synthesis in susceptible bacteria through binding to the 30S ribosomal subunit. This mechanism effectively blocks the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby preventing the addition of new amino acids to the nascent peptide chain.

Fórmula: C₂₂H₂₄Cl₂N₂O₈

Pureza: Min. 89.5%

Cor e Forma: Yellow Powder

Peso molecular: 515.34 g/mol

Ref: 3D-AC20413

Chlorotetracycline monohydrochloride, Antibiotic for Culture Media Use Only

CAS: 64-72-2

Chlorotetracycline monohydrochloride is an antibiotic designed for culture media use. It is derived from the bacterium *Streptomyces aureofaciens*, and functions primarily by inhibiting bacterial protein synthesis. This action prevents the attachment of aminoacyl-tRNA to the ribosomal acceptor site, effectively halting the growth of bacteria by disrupting protein production, which is essential for their survival and replication.

Fórmula: C₂₂H₂₄Cl₂N₂O₈

Pureza: (Chlortetracycline Hcl) Min. 89.5%

Peso molecular: 515.34 g/mol

Ref: 3D-C-5490

Lymecycline EP Impurity G

CAS: 64-72-2

Fórmula: C₂₂H₂₃ClN₂O₈HCl

Peso molecular: 478.88 : 36.46

Ref: ST-EA-CP-L64007